Alignment of subfamily 4

Alignment of P₄ ATPases (Potentially phospholipid transporting)

The alignment was performed on The Danish Biotechnological Database with the programme CLUSTALW with default settings. The alignment of the N- and C-termini was refined by hand.
The grouping of P-type ATPases and the nomenclature is adopted from the work described in Axelsen, K.B. & Palmgren, M.G. (1998) J. Mol. Evol. 46: 84-101.
The sequence numbers refer to the position of the sequence in a phylogenetic tree of P-type ATPases.
The sequences with sequence numbers in parantheses are not included in the phylogenetic tree, but show more than 90 % sequence identity with the sequence with the specified number.
The positions of the transmembrane helices are predicted with the TMHMM server at The Center for Biological Sequence Analysis and the method of von Heijne. The positions might, therefore, be slightly different in the proteins in vivo.
The segments a-h conserved in all P-type ATPases are the amino acid stretches used for the phylogenetic analysis.
Amino acids in the alignment shown in CAPITALS are present in 80% (28 of 35) of the P₄ ATPases.
Number Accession    Organism                  Name
used   number                                               1                                                                                                    100 101                                                                                                  200 201                                                                                                  300 301                                                                                                  400 401                                                                                                  500 501                                                                                                  600 601                                                                                                  700 701                                                                                                  800 801                                                                                                  900 901                                                                                                 1000 1001                                                                                                1100 1101                                                                                                1200 1201                                                                                                1300 1301                                                                                                1400 1401                                                                                                1500 1501                                                                                                1600 1601                                                                                                1700 1701                                                                                                1800 1801                                                                                                1900 1901                                                                                                2000 2001                                                                                                2100 2101                                                                                                2200 2201                                                                                                2300 2301                                                                                                2400 2401                                                                                                2500 2501                                                                                                2600 2601                                                            2665
   8   O45878    Caenorhabditis elegans      F36H2.1        .................... .................... .................... .................... .................... .................... .................... .mnqhfsfilflftfhllst fitsrlirplrvffyshfeh ssvhshffnyslfhfklccr slfsrrrvlhsrtvrvgygp vghdanvtftpNtvcnqkYn ifsFvPivlfqQFk.fflNl yFllmacsqfipaiq.igap itywgPlgfvltitlireaf dDfvrylrDrdlNsekyekl trdgtr.............. .................... .................... .................... .................... .................... ieirsadievGdviimhkdr rvPADvvlLrttdksgacfi rTdqLDGETdwKlripvpht qhlpne......adimelnc evyaekPqkdihafvgtlki .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...........tdddnvqdg slnvenvlwantvvas.gta vGiVvytGretrsvmNttl. pesKvglldlevnnltkllf cfvlvlssvmvamkgld... .................... ...............nlwyr ylmrfillfsyiiPISLrvn ldmaklfyswqIgrDkhip. .................... .................... .................... .................... .................... ...............etvir sstipEeLGrisfllSDKTG TLTkNeMhFkkihlgtv.af s................... .................... .................... .................... .................... .................... .................... .................... ..................sd afeevgqhvrsayagrlakh sfsaklqnaveaialCHnvt pife................ ..................ng eisYqAaSPDEvALVkwtet vgvrlasRdlh......... .................... .................... .................... .................... ......amslsvqlpngqtl mkqfqiLyvfpFtSetKRMg iivkdet............. .................... .................... .................... .................... ....tdevtllmKGADtvms gmvqyn.............. .................... .................... .................... .................... .................... .................... .................... .............dwldeec snmAreGLRTLvvarkplsq aeleafdrayhaAkmsisd. RsqnmanvvnrmlErdLqLl clTgvEDrLQdqVttslelL rnAgIkiWmLTGDKlETAic IakssgLfsrsdnihvfg.. ...............nvhnr tdahn............... .................... .................... .................... ........elnnlrrktdva lvmpGsalnvclqy...... ..yeaevaelvcactaVvCC RcsPeQKaqiVqllrkyrap lrvaAIGDGgNDVsMIQaAh aGiGIdanEGkQAslaaDfs itqFshvcrLLlVHGrfcYk Rscalsqfvmhrgliistmq aifscvfyfasvslyqgvlm vaystcyTmlPvfsl.vvdr dvtatnaltyPeLYkelgk. grslsyktFciwvlislyqg avimyg...allvfdad... ......fihvvsisfsaliv telimvamtvhtWh...... wamllaqalSlglymislil fdqyfd.............. ..rqfvlswvfiskttaita vsclplyivkalrrkfspps yakvn............... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   P91203    Caenorhabditis elegans      F02C9.3        .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..msrqralhsrtvrigygp idhdsprtfppNtvrnqkYn ifsFvPvvlfqeFk.fflNl yFlimafsqlvpifk.igal vtywfPlgfiltitlireai eDfarflrDrelNsekyekl trdgtr.............. .................... .................... .................... .................... .................... veiksadikvGdvivmhkdr rvPADvvlLrtsdkssscfi rTdqLDGETdwKlkipipft qhlane......seimelnc evyaekPqkdiysfvgtvki .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...........taddkiheg sldvenvlwantvvss.gta iGvVvytGcetrsvmNttv. peyKvglldleinnltkllf cfvlllasvmvlmkgpt... .................... ...............slwyl ylarfillfsyiiPISLrtn vdmaklfyswqIghDhhip. .................... .................... .................... .................... .................... ...............etvvr sstipEeLGrisfllSDKTG TLTkNeMhFkkihlgtv.af s................... .................... .................... .................... .................... .................... .................... .................... ..................gd aleeveqhvksaydsalvkh pfsaklknaveslalCHnvt pvle................ ..................ng elsYqAaSPDEvALVkwtet vgvklahRdlh......... .................... .................... .................... .................... ......tmtldvqpsngttv piqfqiLhvfpFtSeRKRMg iivkeet............. .................... .................... .................... .................... ....sgevtlyiKGADtvms dmvqyn.............. .................... .................... .................... .................... .................... .................... .................... .............dwldeec tnmAreGLRTLvfakkilsr aeleafdqayhaAkmsitn. RtqnmanvvknmlErdLqLi clTgvEDrLQdqVttslelL rnAgIkiWmLTGDKlETAic IakssgLfsksdhihvfg.. ...............svqtr tdayn............... .................... .................... .................... ........eldnlrnktnia lvmpGsslniclqy...... ..yeeevaelvcastaVvCC RcsPeQKaqiVqllrkyrap lrvaAIGDGgNDVsMIQaAh aGiGIdanEGkQAslaaDfs itqFshicrLLlVHGrfsYk Rsctlaqfimhrgllisivq aifscvfyfvavslyqgvlm vaftscyTllPvfsl.iadr dvtatnaltyPeLYkelvk. grtlsyktFfiwvfisiyqg avimyg...allifdtd... ......ilhivsisfsalia telimvaltvhtWh...... wlmlvaqalSlglyvvslit ldqffd.............. ..rkfvfswvfitkttaitv vsslplyfiktlrrkfspps fakvk............... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   O70228    Mus musculus                ATP9A          .................... .................... .................... .................... .................... .................... .................... .................... ................mtds iplqpvrhkkrvdsrpragc cewlkccgggeprprtvwlg hpekrdqryprNvinnqkYn fftFlPgvlfsQFr.yffNf yFlllacsqfvpemr.lgal ytywvPlgfvlavtiireav eeircyirDkemNsqiysrl tsrgt............... .................... .................... .................... .................... .................... vkvkssniqvGdlilveknq rvPADmifLrtsekngscfl rTdqLDGETdwKlrlpvact qrlpta......adllqirs yvyaekPnidihnflgtftr .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...........ensdppise slsientlwagtvias.gtv vGvVlytGkklrsvmNtsd. prsKiglfdlevncltkilf galvvvslvmvalqhfa... .................... ...............grwyl qiirflllfsniiPISLrvn ldmgkivyswvIrrDskip. .................... .................... .................... .................... .................... ...............gtvvr sstipEqLGrisylltDKTG TLTqNeMvFkrlhlgtv.ay g................... .................... .................... .................... .................... .................... .................... .................... ....ldsmdevqshifsiyt qpsqdppaqkgptvttkvrr tmssrvheavkaialCHnvt pvyecngvtdqaeaekqf.. .................eds crvYqAsSPDEvALVqwtes vgltlvgRdqs......... .................... .................... .................... .................... ......smqlrtpgdq.... ilnltiLqvfpFtyesKRMg iivrdes............. .................... .................... .................... .................... ....tgeitfymKGADvvma givqyn.............. .................... .................... .................... .................... .................... .................... .................... .............dwleeec gnmAreGLRvLvvakkslte eqyqdfearyvqAklsvhd. Rslkvatvi.eslEmemeLl clTgvEDqLQadVrptletL rnAgIkvWmLTGDKlETAtc taknahLvtrnqdihvfr.. ...............lvtnr geahl............... .................... .................... .................... ........elnafrrkhdca lvisGdslevclky...... ..ydyeFmelacqcpaVvCC RcaPtQKaqiVrllqe.rtg kltcAvGDGgNDVsMIQesd cGvGveGkEGkQAslaaDfs itqFkhLgrLLmVHGrnsYk Rsaalsqfvihrslcistmq avfssvfyfasvplyqgfli igystiyTmfPvfsl.vldk dvksevamlyPeLYkdllk. grplsyktFliwvlisiyqg stimyg...alllfese... ......fvhivaisftslil tellmvaltiqtWh...... wlmtvaellSlacyiaslvf lhefid.............. ..vyfiatlsflwkvsvitl vsclplyvlkylrrrfspps ysklts.............. .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   O75110    Homo sapiens                ATP9A          .................... .................... .................... .................... .................... .................... .................... .................... ................mtdn iplqpvrqkkrmdsrpragc cewlrccgggearprtvwlg hpekrdqryprNvinnqkYn fftFlPgvlfnQFk.yffNl yFlllacsqfvpemr.lgal ytywvPlgfvlavtvireav eeircyvrDkevNsqvysrl targt............... .................... .................... .................... .................... .................... vkvkssniqvGdliiveknq rvPADmifLrtsekngscfl rTdqLDGETdwKlrlpvact qrlpta......adllqirs yvyaeePnidihnfvgtftr .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...........edsdppise slsientlwagtvvas.gtv vGvVlytGrelrsvmNtsn. prsKiglfdlevncltkilf galvvvslvmvalqhfa... .................... ...............grwyl qiirflllfsniiPISLrvn ldmgkivyswvIrrDskip. .................... .................... .................... .................... .................... ...............gtvvr sstipEqLGrisylltDKTG TLTqNeMiFkrlhlgtv.ay g................... .................... .................... .................... .................... .................... .................... .................... ....ldsmdevqshifsiyt qqsqdppaqkgptlttkvrr tmssrvheavkaialCHnvt pvyesngvtdqaeaekqy.. .................eds crvYqAsSPDEvALVqwtes vgltlvgRdqs......... .................... .................... .................... .................... ......smqlrtpgdq.... ilnftiLqifpFtyesKRMg iivrdes............. .................... .................... .................... .................... ....tgeitfymKGADvvma givqyn.............. .................... .................... .................... .................... .................... .................... .................... .............dwleeec gnmAreGLRvLvvakkslae eqyqdfearyvqAklsvhd. Rslkvatvi.eslEmemeLl clTgvEDqLQadVrptletL rnAgIkvWmLTGDKlETAtc taknahLvtrnqdihvfr.. ...............lvtnr geahl............... .................... .................... .................... ........elnafrrkhdca lvisGdslevclky...... ..yeyeFmelacqcpaVvCC RcaPtQKaqiVrllqe.rtg kltcAvGDGgNDVsMIQesd cGvGveGkEGkQAslaaDfs itqFkhLgrLLmVHGrnsYk Rsaalsqfvihrslcistmq avfssvfyfasvplyqgfli igystiyTmfPvfsl.vldk dvksevamlyPeLYkdllk. grplsyktFliwvlisiyqg stimyg...alllfese... ......fvhivaisftslil tellmvaltiqtWh...... wlmtvaellSlacyiaslvf lhefid.............. ..vyfiatlsflwkvsvitl vsclplyvlkylrrrfspps ysklts.............. .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   Q9Y088    Entamoeba histolytica                      .................... .................... .................... .................... .................... .................... .................... .................... .................... .............mnkawdf lqkkipflrkkpeqprtiii pitkqnkkfcsNkvennrYt ylnyiPkclfnQFk.yfyNl yFlitalsqfvpilq.vgyr ftytmPlafvvilamakday dDiririrDkqtNsqpftql iggep............... .................... .................... .................... .................... .................... keiqskdivvGnilklkkde rvPADcliLrsteesgsifi rTdqLDGETdwKlrraiget qkmd......iqticn.sqf elnveaPhadvysfqgtiri .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .............nedpkiy slnventawantivasdemc alviytg......ndtrlar nrkqsgnvkrgktedevnfl skilfcslmglsilmimpdl iqh................. .............pnwfilv sltrfmilfssiiPISmrvn ldiakmvyaffInrDkdia. .................... .................... .................... .................... .................... ...............gaevr nstlpEeLGrvdfvlSDKTG TLTkNeMtFqvlcmqse.ti r................... .................... .................... .................... .................... .................... .................... .................... .............stnfddi kddireclqsneekvlfkkk knpkfimrcvqamalCHnvt psfneng............. .................... ekyYqAsSPDEvALVkfaes vgvvleeRtfk......... .................... .................... .................... .................... ......kivlnmpmig.... nveyeiLnvfpFsSstKRMg iivrnnkdn........... .................... .................... .................... .................... ......eiyllmKGADnvms kiikdn.............. .................... .................... .................... .................... .................... .................... .................... .............ewlseec nnlAreGLRTLvfgsrkmsq eeyqafnerydhAntlmtg. Reeevlkvq.esiEhgLnam ciTgvEDeLQedVqktlemL kqAnvrvWmLTGDKvETAtc IakstkLvdidqeiiqffan s...............idea tslifnnegsi......... .................... .................... .................... ................gtka livdGntlslmlke...... ..mskeFiqfalkaqaVvCC RclPsQKadiVrlvks..sg lttcAIGDGgNDVsMIQeAd vGlGIeGkEGkQAsmaaDfs ikqFshmlkLLlwHGrnsYi Rtsdlalfimhrgmiisimq avfsmvfyftpitlftgill vgystfyTmaP.vfslvlde rislkdimqfPvLYaemqk. gqnlsfktFsawmfisilqg svimmlamilf......... ...dssfvhivsisftvlil iellnigftirrWn...... wiifaseasSvlmylisiiv lrptfe.............. ..psfvfslgfwwrvavitl insfp.filkfiyellnppk hmtvghkkfpisfdltcccn chnirkkndyqdinfseiyd ktetnddstkalidhln... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
   9   P40527    Saccharomyces cerevisiae    yil048w        .................... .................... ...................m pnppsfkshkqnlfnsnnnq hansvdsfdlhlddsfdaal dslqinnnpeplskhntvgd resfemrtvddldnfsnhss dshrkssntdthplmydnrl sqddnfkftniassppsssn nifskalsylkvsntknwsk fgspielsdqhiereihpdt tpvydrnryvsNelsnakYn avtFvPtllyeQFk.ffyNl yFlvvalsqavpalr.igyl ssyivPlafvltvtmakeai dDiqrrrrDresNnelyhvi trn................. .................... .................... .................... .................... .................... rsipskdlkvGdlikvhkgd riPADlvlLqssepsgesfi kTdqLDGETdwKlrvacplt qnlsen......dlinri.. sitasaPeksihkflgkvty .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..............kdstsn plsvdntlwantvlassgfc iacVvytGrdtrqamNttt. akvKtglleleinsiskilc acvfalsillvafagfhn.. .................... ...............ddwyi dilrylilfstiiPvSLrvn ldlaksvyahqIehDktip. .................... .................... .................... .................... .................... ...............etivr tstipEdLGrieyllSDKTG TLTqNdMqlkkihlgtv.sy t................... .................... .................... .................... .................... .................... .................... .................... ......setldivsdyvqsl vsskndslnnskvalsttrk dmsfrvrdmiltlaiCHnvt ptfe................ .................dd. eltYqAaSPDEiAiVkftes vglslfkRdrh......... .................... .................... .................... .................... ......sisllhehsgk... tlnyeiLqvfpFnSdsKRMg iivrdeq............. .................... .................... .................... .................... ....ldeywfmqKGADtvms kivesn.............. .................... .................... .................... .................... .................... .................... .................... .............dwleeet gnmAreGLRTLvigrkklnk kiyeqfqkeyndAslsmln. RdqqmsqvitkylEhdLeLl GlTgvEDkLQkdVkssielL rnAgIkiWmLTGDKvETArc vsisakLisrgqyvhtit.. ...............kvtrp egafn............... .................... .................... .................... ........qleylkinrnac llidGeslgmflkh...... ..yeqeFfdvvvhlptViaC RctPqQKadvalvirk.mtg krvccIGDGgNDVsMIQcAd vGvGIvGkEGkQAslaaDfs itqFchLteLLlwHGrnsYk Rsaklaqfvmhrgliiaicq avysicslfepialyqgwlm vgyatcyTmaPvfsl.tldh dieesltkiyPeLYkelte. gkslsyktFfvwvllslfqg sviqlfsqaftslldtd... ......ftrmvaisftalvv nelimvaleiytWn...... ktmlvteiatllfyivsvpf lgdyfd.............. ..lgymttvnyyagllvill isifpvwtakaiyrrlhpps yakvqefatp.......... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
  10   Q10309    Schizosaccharomyces pombe   SPAC6C3.05c    .................... .................... .................... .................... .................... .................... .................... mdsrlnriqskmklwikdkn lsnpsiplkvlnksfrssrq ssvsnghglysldrdetesl mssheasnagisldssfrvi qvgqpepqygnNavtntkYd lftFlPkclyeQFr.yfyNm yFllvslsqlipplk.igyl styiaPlifvllitltkeav dDlkrrrrDsyaNneiytvn d................... .................... .................... .................... .................... .................... spcaaqniqaGdvvyiakdq riPADmilLettvgn.eafi rTdqLDGETdwKlripcsnq hteg................ ivhadaPiksvhhfygtftl .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............nnqkr pisvdhtlwantvlasdg.v yGvVvytGkdtrqsmNssk. aktKvgllekeinfyskilc tfvlvlsigltfshgik... .................... ...............tdwyi svfrylilfssiiPInLrvn ldlakivhskntesDpnlp. .................... .................... .................... .................... .................... ...............gvvvr ssnipEeLGrieyvltDKTG TLTqNeMemkklhvgtm.gf s................... .................... .................... .................... .................... .................... .................... .................... ..................ae smdvvqaciqnystpiplse dsktlvrnlvlalslCHnvt pskg................ .................hdg vvsYqAaSPDEvAiVkwtst lglvltnRtrd......... .................... .................... .................... .................... ......aitlnnn....... ..vykiLnifpFkSetKRMg iivqsp.............. .................... .................... .................... .................... ....dekitfylKGADsimq nfvkps.............. .................... .................... .................... .................... .................... .................... .................... .............fwleeec gnlAreGLRTLvvakkdlsa eeysafslahsdAslsfsns RdkkmeeivsrylEndmdLl GlTgvEDkLQkdVkitlelL rnAgIhvWmLTGDKvETArc IaissrLvsrgqyihtin.. ...............qlssr eeahn............... .................... .................... .................... ........hlltlrnkpdsc liidGesmefcigy...... ..lqneFidivsdlssVviC RctPtQKanmtrliqe.kkq asvccIGDGgNDVgMIQvAn vGiGIvGkEGqQAslaaDys vkeFshvsrLLlwHGrisYk qtsklamfvihrgllisvcq vvysvisafepialfqglll vgystmyTmlPvfsi.vydr dvseklvflfPeLYkemre. qkcfsyknFiscvlisvyqg liiqlftfyligfeee.... .......gkmlavcfsclif nelimvalqintWe...... qtivmselltlmmyilsvpf ltnyfe.............. ..lkfllglkfywvsalilf isllpvwcgkalkrklkpss yaklqr.............. .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   O61137    Leishmania donovani         APLT1          .................... .................... .................... .................... .................... .................... .mrqiryralhngadedars rnsstpnistssahgpqlpq rhccrprdfvfddslstgaa vsvlaipqqkkhsvrrwlqe mlhlpiapsldnrqipfgyf pgewspvgypsNavsnrrYt lstFlPlallrQFq.nffNl fylflafsqvipvlk.vgfi ftyfsPlvmvvclslmkdal dewkrfrrDriaNvevfekl tgggd............... .................... .................... .................... .................... ...................v vtvrsshirvGdllilhqdq rvPADcvvLhtseksgttfi rTdqLDGETdwKlryplnst kglg.....yaelgacastc tvarltktstaspapsn... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............wptdr asrsrwrmpsgrrvwwrrgr wwlpsytrvgrraalNsts. prnKlglierelnliavlcf alllilsfllvaqqqfr... .................... ...............gdfav mfvrffillssmiPISmrvn vdvgrlwysydmshDpnip. .................... .................... .................... .................... .................... ...............gavar nanlpEeLGrlrylfSDKTG TLTkNkMkFrvmqvgpd.tv lt.................. .................... .................... .................... .................... .................... .................... ................drft dqlagalqeyfgtgnwgaga rlmlsnvsarvsvrnskqws rdvqrvgdliraivlCHnvs pvvmeeplalgtddettalg rgaaaavpattdmr....sq ptdYqAsSPDEvALVkfcgs lgivltyRdlt......... .................... .................... .................... .................... ......tiaftvgggaq... lhtctivktfpFsSeRKcMg iilrertgscsg........ .................... .................... .................... .................... .gssqetvkfymKGADvkma svvrqs.............. .................... .................... .................... .................... .................... .................... .................... .............ewleecc qelAqmGLRTLvfasrtlse emlgaflqqyeaAisilgeg Raaaieaam.kllEtdmtLt GvTgvEDeLQddVvvcletL gmcgIkvWmLTGDKvETAit IgrstrLiprhcrieylcg. ................mapa dighr............... .................... .................... ..................lh elqeefcwgvtcgsivppwt lvldGnalayclsh...... ...asfFadvartaysViva RcsPtQKaavVtvmrdscrd arvaAIGDGgNDVsMIQaAn vGiGIeGlEGkQAsmaaDfs itkFshclrLimwHGrnsYq Rtcrlsqfimhrgivysvvq tvfsvlfagttmsvfngyll mgystvfTmaPafal.vlde dfnesdvheyPfLYkdllk. arsmntrtFlqwvwasffqg gvmmlmalqlfks....... ..dmfqivtiaytsllitel aivgatahlrilWrerrarf flflcsevvSllmfflavvv lpdtfd.............. ..rdfffswscwwrvavicl asiaplmifqmvgkyilfnp riavscmgcrt......... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
  11   Q10463    Caenorhabditis elegans      T24H7.5        .................... .................... .................... .................... .................... .................... .................... .................... ......mttprpthlhrrss skwvppsaplhnpisifrgr snretgsrvirpnhlfespr yelnnyrdftdNristtkYt fwnFiPlniwhQvstkyaNl yFifiailnwvpffd.aytr yvgliPicfvlgttlikdgi eDyrrykfDnqiNkktchvw drdr................ .................... .................... .................... .................... .................caf rktewryilvGdfvhisnnq dvPADiilLrsssesgtcyi eTcnLDGETslKqrmvpakv idyskkd...stfkppdftg vvtcekPdksiytirakvef .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..............epgqsd viikenmllrgsriknttfv eGiVvyaGhdtkvmqNngr. aphKtsgiekltnkfiiacf imlllmvlygaitsavwvgq h...pvdeqipfilsntpr. .............pfiegfi gigaffinyqllvPISLyit veiikalqiyfIsnDiqlyd qk.................. .................... .................... .................... .................... ............sdraidcr slsipEeLGtvthvlSDKTG TLTeNmMiFrncafdet.dy gsngsqsnpdkpvksde... .................... .................... ..............lyqril tsmqnpvqkhffanillnns vvvnhiphtdvlelgnfdgg vynignscfydvteekykqk laaigkggvddddvsrpdel glpttsiqfddrltviveed tpsdspapdasprdlpetpt ptspiyrplsslssfsrkls tvvrrsilrpisdiipvrkr ............lisfkqqa mnpYeAeSPDElALiegaal ydyvlleRaats........ .................... .................... .................... .................... .....vtistpekaek.... ..ryeiLltlpFdatRKRMs vivnsqkg............ .................... .................... .................... .................... .......plmycKGADsaii srlssdslesk......... .................... .................... .................... .................... .................... .................... .................... ...........rvqdlkdhl dnyAkkGLRTLcfamkyisk edfedfldsyrflmedatse Rekmlseka.delEtnLkLs GvTgiEDrLQdgVpdtlraL rdAgIqvWvLTGDKlETAqn IatssgLfhpqrslkviet. ...............etdae eases............... .................... .................... .................... ................agln iimspaairlaqdg...... ...nahlmealkkaktVlCy RmtPseKatiVntvkk.rik gnvlAIGDGaNDVpMIQaAh vGiGIaGkEGlQAamacDfa iarFkfLsrLLlVHGhwsYy Rlantflyflyknanavfii fyyqfyngasgtnivdpiwg viypiifTsvqpvvvgvldq dyddqtlmnkPeLYvigre. nqlytwkhFfrdvidgiyqa aviyyvayltldnstss... ......lwemgfyiatssil vnsghlalqvryWh...... wqlvalfsffilfnfafffa ecltaaaamvpdp....pvw mpihamgdprfwyyqfitvi valcprqsiekqnmaelnfi elqcrimfelafiavlvaga vyvfmtlrkngffvtvepsv ttspknldkpltvyykyhlg pyqnvmnvigeakqllassp tpatffgiyydnpevtdshf lqsavgvvfgsdgndfhsek yskdltdngfeklvlpnver avqvtqpstggfasflalvw ftystirkyisenklettya vefytnteinvifpldnane flvkdyqsidkleseaakkr fdsseedsesepegaeepat eeneq
   -   O18182    Caenorhabditis elegans      W09D10.2       .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..mlpqqrlvvpnnqkeppp ryeqpnrkycgNristtkYs vltFiPknlfeQlh.raaNl yFifivilnmi..ig.afgk yisvlPiafvlgitaikdaf eDyrryksDqkiNhstcrvw dasqqr.............. .................... .................... .................... .................... ...................y rklewqnilvGdfvhlshde iiPADillLrssdvngvcyv eTcnLDGEsnlKqrqairsm gkyhnanvp.leyspaefny riaceqPttdvykfegrlea .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ........ieggpplareft ilakenvllrgcvvkntdfv eGiVlyaGkdtkamlNnng. pryKrsslekmtnvdilwsv ctllalcvigavlsgvwlrt f...stpyivpflvfihpns syhnnndsqykyspsyeswf sfwsyiivlqvmiPISLyvs iefikifqvwfmsqDrnmyy dk.................. .................... .................... .................... .................... ............vdkrlqcr alnitEeLGqiqyvmSDKTG TLTeNqMvFrrcsvngn.dy ggrpvvdavdsslelvastl rsdqptekklqmaalaeaaa ktrrlrpsrdpalesqlass vlklgadiddpvfaffltma icntvvvnakphedlmdpdg divnsrfapeevsprrgssl edgfkyladveeespas.tq astpvmiteendgfeeieli efpevktdetqmtekeetis aevaakksgsdekdnnynge rkegkgfgilhrpsils.vp faklkgmkspfrrsvdkrss ss.........tetavappl hsfYdseSPDElALVeaare ygirllrRrfd......... .................... .................... .................... .................... ......dvivylrhsts... svkykvLhtlpFdadRKRMs viiressg............ .................... .................... .................... .................... ....lkriivltKGADatvi pvlseafstsargee..... .................... .................... .................... .................... .................... .................... .................... ...........vifksqehl tqyAkeGLRTLclsmkiwte eeyqgwkekheeAeldmmd. ketmlaest.lraEqdLeLl GvTaiEDrLQdgVpecihsL reAgIrvWvLTGDKiETAvn IayssrLfspsmdllnigan ...............gvrav sdllt............... .................... .................... ...................e hlkriarayevsadaadsfg lvlnastmsycldp...... .hnlerFvkllrgcrsVlCC RatPlQKaqlVnlakn.hlk gkvlAIGDGaNDVsMIQgAd vGiGlsGqEGmQAvmssDfa marFrfLsnLLlVHGhwnYy Rlaqtilyffyknamlvfvi fwyqifngfsaqvpidpvyl mvynlifTsvPpllfgcldq dasaellldcPrLYeqgrl. gkryrwysFwinmldavwqs lvvfficyftyrg.....sn ....vdmwtfghllvtqlii vntfhlalfvqyWt...... wpmfwsmflSvllfficall yngfvtanwtwtnvkdppsm vslksfsslefwmaliisvv lcltpryvlttvvntvspst tlrtrlgaedgfkkktesrf tacavgclsapfkcarmccq ktkpadvhvsskivfnilf. .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   O60312    Homo sapiens                ATP10C         .................... .................... .................... .................... .................... .................... .................... .................... ......merepagteepgpp g....rrrrregrtrtvrsn llpppgaedpaagaakgerr rrrgcaqhladNrlkttkyt llsFlPknlfeQFh.rpaNv yFvfiallnfvpavn.afqp glalaPvlfilaitafrdlw eDysrhrsDhkiNhlgclvf sreekk.............. .................... .................... .................... .................... ...................y vnrfwkeihvGdfvrlrcne ifPADillLsssdpdglchi eTanLDGETnlkrrqvvrgf selvs......efnpltfts viecekPnndlsrfrgciih .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..............dngkka glykenlllrgctlrntdav vGiViyaGhetkallNnsg. pryKrsklerqmncdvlwcv lllvcmslfsavghglwiwr y...qekk.slfyvpksdgs sl..........spvtaavy sfltmiivlqvliPISLyvs ieivkacrvyfInqDmqlyd ee.................. .................... .................... .................... .................... ............tdsqlqcr alnitEdLGqiqyifSDKTG TLTeNkMvFrrctvsgv.ey sh....danaqrlaryqead seeeevvprggsvsqrgsig shqsvrvvhrtqstkshrrt gsraeakrasmlskhtafss pmekditpdpkllekvsecd kslavarhqehllahlspel sdvfdffialticntvvvts pdqprtkvrvrfelk..spv ktiedflrrftpscltsgcs sigslaanksshklgssfps tpssdgmllrleerlgqpts aiasngyssqadnwaselaq ..............eqeser elrYeAeSPDEaALVyaara yncvlveRlhd......... .................... .................... .................... .................... ......qvsvelphlg.... rltfelLhtlgFdSvRKRMs vvirhp.l............ .................... .................... .................... .................... ....tdeinvytKGADsvvm dllqpcssvdargrhqkk.. .................... .................... .................... .................... .................... .................... .................... ...........irsktqnyl nvyAaeGLRTLciakrvlsk eeyacwlqshleAesslen. seellfqsa.irlEtnLhLl GaTgiEDrLQdgVpetiskL rqAglqiWvLTGDKqETAvn IayackLldhdeevitlnat ...............sqeac aalld............... .................... .................qcl cyvqsrglqrapektkgkvs mrfsslcppststasgrrps lvidGrslayalek...... .nledkFlflakqcrsVlCC RstPlQKsmvVklvrs.klk amtlAIGDGaNDVsMIQvAd vGvGIsGqEGmQAvmasDfa vpkFryLerLLilHGhwcYs Rlanmvlyffykntmfvgll fwfqffcgfsastmidqwyl iffnllfsslPplvtgvldr dvpanvlltnPqLYksgqn. meeyrprtFwfnmadaafqs lvcfsipylayyd.....sn ....vdlftwgtpivtiall tfllhlgietktWt...... wlnwitcgfSvllfftvali ynascatcyppsn....pyw tmqallgdpvfyltclmtpv aallprlffrslqgrvfptq lqlarqltrksprrcsapke tfaqgrlpkdsgtehssgrt vktsvplsqpswhtqqpvcs leasgepstvdmsmpvreht lleglsapapmssapgeavl rspggcpeeskvraastgrv tplsslfslptfsllnwiss wslvsrlgsvlqfsrteqla dgqagrglpvqphsgrsglq gpdhrlligassrrsq.... .................... .................... .....
   -   O54827    Mus musculus                ATP10C         .................... .................... .................... .................... .................... .................... .................... .................... ......merelpaaeesass gwrrprrrrwegrtrtvrsn llpplgtedstigapkgerl lmrgciqhladNrlkttkYt llsFlPknlfeQFh.rlaNv yFvfiallnfvpavn.afqp glalaPvlfilavtaikdlw eDysrhrsDheiNhlgclvf sreekk.............. .................... .................... .................... .................... ...................y vnrywkeirvGdfvrlccne iiPADillLsssdpdglchi eTanLDGETnlKrrqvvrgf selvs......efnpltfts viecekPnndlsrfrgyimh .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..............sngeka glhkenlllrgctirnteav aGiViyaGhetkallNnsg. pryKrsqlerqmncdvlwcv lllvcislfsavghglwvrr y...qekk.alfdvpesdgs sl..........spataavy sfftmiivlqvliPISLyvs ieivkvcqvyfInqDielyd ee.................. .................... .................... .................... .................... ............tdsqlqcr alnitEdLGqikyifSDKTG l................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
PartialO94823    Homo sapiens                ATP10B         .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..............knlltk vrdaalwletlsdsrpakas lsttssiadfflalticnsv mvsttteprqrvtikpsska lgtslekiqqlfqklkllsl sqsfsstapsdtdlgeslga nvattdsderddasvCsggd stddggyrssmwdqgdiles gsgtsleealeapatdlarp efcYeAeSPDEaALVhaaha ysftlvsRtpe......... .................... .................... .................... .................... ......qvtvrlpqgt.... cltfslLctlgFdSvRKRMs vvvrhp.l............ .................... .................... .................... .................... ....tgeivvytKGADsvim dlledpacvpdinmekklrk .................... .................... .................... .................... .................... .................... .................... ...........irartqkhl dlyArdGLRTLciakkvvse edfrrwasfrreAeasldn. Rdellmeta.qhlEnqLtLl GaTgiEDrLQegVpdtiatL reAgIqlWvLTGDKqETAvn IahscrLlnqtdtvytinte ...............nqetc esiln............... .................... .................cal eelkqfrelqkpdrk..lfg frlpsktpsitseavvpeag lvidGktlnaifqg...... .klekkFleltqycrsVlCC RstPlQKsmiVklvrd.klr vmtlsIGDGaNDVsMIQaAd iGiGIsGqEGmQAvmssDfa itrFkhLkkLLlVHGhwcYs Rlarmvvyylyknvcyvnll fwyqffcgfssstmidywqm iffnlffTslPplvfgvldk disaetllalPeLYksgqn. secynlstFwismvdafyqs licffipylaykg.....sd ....idvftfgtpintislt tillhqamemktWt...... ifhgvvllgSflmyflvsll ynatcvicnsptn....pyw vmegqlsnptfylvcfltpv vallpryfflslqgtcgksl iskaqkidklppdkrnleiq swrsrqrpapvpevarpthh pvssitgqdfsastpkssnp pkrkhveesvlheqrcgtec mrddscsgdssaqlssgehl lgpnrimaysrgqtdmcrcs krsshrrsqsslti...... .................... .................... .................... .................... .................... .....
  12   Q27720    Plasmodium falciparum       PfATPase2      .................... .................... .................... .................... .................... .................... .................... .................... ..........myeqfhkisn vyfffigilqvipqftatng iptvffpllivltanaikda fedwnrhktdkiennrmcYg ivseeekkiyqeks....Nk knifkklkryffgnr..... .kicntenyydeddmcddei tDindyinnyedNleniegt vk.................. .................... .................... .................... .................... .................... ..krwkdikaGdiilcrrse ffcADillLctshkngiafv eTssLDGETnlKvkeantfl fnilgndrnsaidnvknlkg filsdkPnkdlstmygtiyf ekdkkidvenigiqellkkt teeieyrkkr.......... .................... .................... .................... .................... .................... .................... .................... ...lssvdlsksssaigsnl cnnnnksdsksdiknynkdd ddfddmdennilkndnyiri pfdekqfvlrgcklkntdwi mGiViyvGretkiqmNssk. sikKtskleiltnkmtiiiw viqmiiclisayynaiivss s.....rknrfrylpfnlek akkp..........yivgii sffswvvitgnfvPISLivt msfvkvvqayfIscDknmih kvqadvpsfgeqkeipnipk ddissdadvikrmrtkkiad ssllhidenqteednmdmks dciafknnsshqningnnkq ysssslgiisnapkreissr visfkdskeknyiyfnavpr tssliEeLGqieyifSDKTG TLTcNiMeFrkcaingi.sy g................... .................... .................... .................... .................... .................... .................... ...........kglteikrn ilkkknleipveptmkfkkk tphvniidndiinhlkdpnh fnhvnlinfflhlainHavi cekdkeg............. .................... vttYsssSPDEeALVnaakh fditflyRreg......... .................... .................... .................... .................... ......kygisifgki.... .yeidtLatieFtSkRKmss vicripvinpdynhptdaks snmdkkknnmddhlvvgkne ekeetddlnvyppkkeahsk lnnnnnnnnniridnlyddk nnfniiynhnegrtpevitc knsknskimlfcKGAgsiil kklakr.............. .................... .................... .................... .................... .................... .................... .................... .........tdideitiehm etyAdeGLRTLciaqrelse esfaewyhlykeAslsikd. Reeklesva.eyiEndLiLq GiTgiEDkLQegVsstiedL rmAgIhiWmLTGDKiETAmn IgiaanLidnyseqfiytee yieseealikkidddilmve kslniphynfd......... .................... ...........dennnvede krktffrnnfiknffcaknk sglllnpdkynmlintlnyv lvvdGsvidlllsek..... ..merkFfyladkcssViCg RvsPyQKgaiVssanr.lln kitlAIGDGaNDrnMIntAn iGiGIrGqEGvQAfnssDyg isqFrfLknLLlVHGrlsYr Risklvvymfyknmvlifpl fifgsislysgqkiyfefll hlfnvlfTaiPvvihavldq dislntamekPnLYklgih. hyyfnirtFiswvmnslfhg svvfliplyflsyyniptsd g.ipydiwtvgcatyfltvl ivnfkilfetyyln...... ilpisgialSifsfvllvta fsfmcvgsihllg....... tivylvqslrfwlvvilglf tallrdyvfkvykrnfnpei yhllldqenakigmndvidq lklnefdkdddirieksksl gyafseadpaciqlirkqdn mi.................. .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   O77368    Plasmodium falciparum       MAL3P6.27      .................... .................... .................... .................... .................... .................... .................... .................... ...........mkilewisc tikgkhnenkiylisnfefn kddheyyiknaenrikeedl nidiiygkkhkNeirtakYk lysFlPlivffQFl.rlgNl yFlsismlqlipeitdskgm ptyliPlvfiivvamikeff eDwqrhksDneeNskktmvf vqgelk.............. .................... .................... .................... .................... .................... .ekkwadvkdGdvvkifsye yfPADlivLncsnkkgivni eTknvDGEsnvKqkyclpdi skyfsd.....dktagfcri eliserPndnifdykgymil pplqyknmkngklihfynth ykmddhkdehdekgtgkyin knykndyndkhisyntneqn nlsdmtkndpkeydynpqne innnnnnnncdnnnnncnnn nrffvddikkqgqneetvdk kksffiinnqkkvydtgssn ndqithinndvisekkrasr rrtlynkltfnksffnnkne nkklnkrnstlssinnnndn nnnnnnnnnnihnreydgee qtlkkenfffkeykrdqkfv qitidnlvlrgtslvntkwi yGlVintGnrtklmkNastk srqKwsrlefvygnhvivli icqvfislivaiagvlwmrr k......gytlwylnldqts ds............lktffi tigsmvllfgsfiPvdLlli wevvrllqgylInwDndmys ek.................. .................... .................... .................... .................... ............tgrhalsk agqllEemGnvthiySDKTG TLTqNvMqlqniglgnkgty gfydfsnikenitksrhwgs qdpmdpvleeyeneenvysn vnddnkndhgtnesddnnnn nnnnddddhhdnnhnihndq nnnaqydnydnyylnnhqqq nkvknrpciddetnfyrnnn mnkertrksytflnplnwsn tsintkmkkkkslfynknsl anyesllnntyteddfirge nefvffnrilfvnkiysirh dvqdqiyflllvlslCHsam irnvdidemdnneddnnnne k.lkiydketdivytyitqt qpqYdAsSPDElAListsly lgcefvnRpnlttieielts tfaqrfilgekkfekflekk efyekefdtyfpdisaclgk ekkkdnnkineminnkgntk ddymnnfhmsipiknifgsn kmqykeeikyeekiikkvvp ilsfeiLdvfaFdnvRKRMs livknekk............ .................... .................... .................... .................... ......eifmlvKGADtsvl klasknqen........... .................... .................... .................... .................... .................... .................... .................... ...........ivdhvehql hafAtsGLRTLvlgykylte nefsdmyrnhinArkksetd keeylqefy.eeaEnnLiii GcTgidDkLQddVpqviqdL rdAgmticvLTGDKlETAin Ighsinilnkqtynaiftet dptllleqlnihekntnaan llnvdhgtkwwnsvnwehln ldlrsetilnfmksnfhgsl kksiissnmfnmknnnsfps larqdkvfnsflessesfch nnnemdktkgkekvhysqfs ititGealdvimkdk..... .ilkikFytlarsastliaC RvtPkQKsllVkensafnpr gtslAIGDGaNDVgMIlmAn vGvGIaGkEGlQAarssDft iseFkyLkkLLfVHGreslr Rnsflvyfcifrnvsfclcs milifwtgysaidawnpwtk qiiniafTslPviffvaldk qlphnillnnPlLYetsps. ...tlwp.Fysnrkmefytn kvkgcyk............. .......sfykfcffpiryi pyiqrytekiksWig..... krskpekyrtygthylfvyl lfaiwlat............ vetvimlhfstgqayssslk dnhhvdidfntfsqilythh viavniv............. .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
  13   Q12674    Saccharomyces cerevisiae    ymr162c        .................... .................... .................... .................... ...........mgiadgqrr rssslrtqmfnkhlydkyrg rtddeieledinesktfsgs dnndkddrdetsgnyaaeed yemeeygspdvsysiitkil dtildrrrtfhskdgrhipi ildhnaieykqaatkrdghl iderfnkpycdNritssrYt fysFlPrqlyaQFs.klaNt yFfivavlqmipgws.ttgt yttiiPlcvfmgismtreaw dDfrrhrlDkeeNnkpvgvl vkdgnnd............. .................... .................... aqevytlpssvvsstayltk saaaennpplnddrnssqgh fldthfnnfellknkynvhi hqkkweklrvGdfvlltqdd wvPADlllLtcdgensecfv eTmaLDGETnlKskqphpel nkltkaas.....glanina qvtvedPnidlynfegnlel .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .........knhrndtimky plgpdnviyrgsilrntqnv vGmVifsGeetkirmNalkn prtKapklqrkinmiivfmv fvvatislfsylghvlhkkk y....idqnkawylfqad.. ...............agvap timsfiimyntviPlSLyvt meiikvvqskmmewDidmyh ae.................. .................... .................... .................... .................... ............tntpcesr tatilEeLGqvsyifSDKTG TLTdNkMiFrkfslcgs.sw lhnvdlgnsednfednrdnt nslrlppkahn......... .................... .................... .................gss idvvsigdqnvldrlgfsda piekghrpsldnfpksrnsi eykgnssaiytgrpsmrslf gkdnshlskqasvispsetf senikssfdliqfiqrypta lfsqkakffflslalCHscl pkkthnesig.......... ..................ed sieYqssSPDElALVtaard lgyivlnRnaqi........ .................... .................... .................... .................... .....ltiktfpdgfdgeak lenyeiLnyidFnSqRKRMs vlvrmpnq............ .................... .................... .................... .................... ....pnqvllicKGADnvim erlhdrelaakkmadictst kerkdaeaelvlqqrksler mvdeeamartslrnslssvp raslslqavrkslsmknsrt rdpekqidsidqfletvkks dqeigsvvnksrkslhkqqi ekygprisidgthfpnnnvp idtrkeglqhdydteilehi gsdelilneeyviertlqai defsteGLRTLvyaykwidi gqyenwnkryhqAktsltd. Rkikvdeag.aeiEdgLnLl GvTaiEDkLQdgVseaieki rrAgIkmWmLTGDKrETAin IgyscmLikdystvvilttt de.............niisk mnavs............... .................... .................... .................... ........qevdsgniahcv vvidGatmamfegnp..... .tymsvFvelctktdsViCC RasPsQKalmVsnirntdpn lvtlAIGDGaNDiaMIQsAd iGvGIaGkEGlQAsrvsDys igqFrfLlkLLfVHGrynYi Rtskfmlctfykeitfyftq liyqrytmfsgsslyepwsl smfntlfTslPvlcigmfek dlkpmtlltvPeLYsygrl. sqgfnwliFmewvilattns liitflnvvmwgmsslsdn. ..tmyplglinftaivalin vksqfvemhnrnWla..... ftsvvlscggwlvwccalpi lnntdqiydvayg....... fynhfgkditfwctslvlal lpitldivyktfkvmiwpsd sdifaeleqksdirkklelg aysemrqgwtwdkdpstftr ytdkvlsrprtnsrasakth nssiysmsngnvdhsskknf fgnsskksseryevlpsgkl ikrpslktqsskdsiggnit tkltkklklpsrnvededvn qiiqarlkdle......... .................... .................... .................... .................... .....
  14   Q29449    Bos taurus                                 .................... .................... .................... .................... .................... .................... .................... .................... .................... mptmrrtvseirsraegyek tddvsektsladqeeirtif inqpqltkfcnNhvstakYn iitFlPrflysQFr.raaNs fFlfiallqqipdvs.ptgr yttlvPllfilavaaikeii eDikrhkaDnavNkkqtqvl rnga................ .................... .................... .................... .................... ...................w eivhwekvnvGdiviikgke yiPADtvlLsssepqamcyi eTsnLDGETnlKirqglpat sdikdi......dslmrlsg riecesPnrhlydfvgnirl .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..............dgrstv plgadqillrgaqlrntqwv hGiVvytGhdtklmqNsts. pplKlsnveritnvqililf ciliamslvcsvgsaiwnrr h......sgrdwylnlnygg ..............annfgl nfltfiilfnnliPISLlvt levvkftqayfInwDldmhy ep.................. .................... .................... .................... .................... ............tdtaamar tsnlnveLGqvkyifSDKTG TLTcNvMqFkkctiagv.ay g................... .................... .................... .................... .................... .................... .................... .................... ..............qnsqfg dektfsdssllenlqn..nh ptapiicefltmmavCHtav pere.gd............. .................... kiiYqAaSPDEgALVraakq lnfvftgRtpd......... .................... .................... .................... .................... ......sviidslgqe.... .eryelLnvleFtSaRKRMs vivrtpsg............ .................... .................... .................... .................... ......klrlycKGADtviy drlaetskyk.......... .................... .................... .................... .................... .................... .................... .................... .............eitlkhl eqfAteGLRTLcfavaeise sdfqewravyhrAstsvqn. Rllkleesy.eliEknLqLl GaTaiEDkLQdqVpetietL mkAdIkiWiLTGDKqETAin IghsckLrrknmgmivineg ...............sldgt retls............... .................... .................... .................... ...rhcttlgdalrkendfa liidGktlkyaltf...... .gvrqyFldlalsckaViCC RvsPlQKsevVemvkk.qvk vitlAIGDGaNDVsMIQtAh vGvGIsGnEGlQAanssDys iaqFkyLknLLmVHGawnYn Rgskcilycfyknivlyiie iwfafvngfsgqilferwci glynvmfTamPpltlgifer scrkeymlkyPeLYktsqn. aldfntkvFwvhclnglfhs vilfwfplkalqygtvfen. .grtsdylllgnfvytfvvi tvclkagletsyWt...... wfshiaiwgSialwvvffgi ysslwpavp.mapdmsg... eaamlfssgvfwmgllfipv asllldvvykvikrtafktl vdevqeleaksqdpgavvlg kslteraqllknvfkknhvn lyrseslqqnllhgyafsqd engivsqseviraydttkqr pdew................ .................... .................... .................... .................... .................... .................... .................... .....
 (14)  P70704    Mus musculus                               .................... .................... .................... .................... .................... .................... .................... .................... .................... mptmrrtvseirsraegyek tddvsektsladqeevrtif inqpqltkfcnNhvstakYn vitFlPrflysQFr.raaNs fFlfiallqqipdvs.ptgr yttlvPllfilavaaikeii eDikrhkaDnavNkkqtqvl rnga................ .................... .................... .................... .................... ...................w eivhwekvnvGdiviikgke yiPADtvlLsssepqamcyi eTsnLDGETnlKirqglpat sdikdi......dslmrisg riecesPnrhlydfvgnirl .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..............dghgtv plgadqillrgaqlrntqwv hGiVvytGhdtklmqNsts. pplKlsnveritnvqililf ciliamslvcsvgsaiwnrr h......sgkdwylhlhygg ..............asnfgl nfltfiilfnnliPISLlvt levvkftqayfInwDldmhy ep.................. .................... .................... .................... .................... ............tdtaamar tsnlnEeLGqvkyifSDKTG TLTcNvMqFkkctiagv.ay g................... .................... .................... .................... .................... .................... .................... .................... ..............qssqfg dektfndpslldnlqn..nh ptapiicefltmmavCHtav pere.gd............. .................... kiiYqAaSPDEgALVraakq lnfvftgRtpd......... .................... .................... .................... .................... ......sviidslgqe.... .eryelLnvleFtSaRKRMs vvvrtpsg............ .................... .................... .................... .................... ......klrlycKGADtviy erlaetskyk.......... .................... .................... .................... .................... .................... .................... .................... .............eitlkhl eqfAteGLRTLcfavaeise sdfeewravyhrAstsvqn. Rllkleesy.eliEknLqLl GaTaiEDkLQdqVpetietL mkAdIkiWiLTGDKqETAin IghscrLlkrnmgmivineg ...............sldgt retls............... .................... .................... .................... ...rhcttlgdalrkendfa liidGktlkyaltf...... .gvrqyFldlalsckaViCC RvsPlQKsevVemvkk.qvk vitlAIGDGaNDVsMIQtAh vGvGIsGnEGlQAanssDys iaqFkyLknLLmVHGawnYn Rvskcilycfyknivlyiie iwfafvngfsgqilferwci glynvmfTamPpltlgifer scrkenmlkyPeLYktsqn. aldfntkvFwvhclnglfhs vilfwfplkalqygtvfgn. .gktsdylllgnfvytfvvi tvclkagletsyWt...... wfshiaiwgSialwvvffgi ysslwpavp.mapdmsg... eaamlfssgvfwvgllsipv asllldvlykvikrtafktl vdevqeleaksqdpgavvlg kslteraqllknvfkknhvn lyrseslqqnllhgyafsqd engivsqseviraydttkqr pdew................ .................... .................... .................... .................... .................... .................... .................... .....
 (14)  Q9Y2Q0    Homo sapiens                ATP8A1         .................... .................... .................... .................... .................... .................... .................... .................... .................... ...mrrtvseirsraegyek tddvsektsladqeevrtif inqpqltkfcnNhvstakYn iitFlPrflysQFr.raaNs fFlfiallqqipdvs.ptgr yttlvPllfilavaaikeii eDikrhkaDnavNkkqtqvl rnga................ .................... .................... .................... .................... ...................w eivhwekvavGeivkvtnge hlPADlisLsssepqamcyi eTsnLDGETnlKirqglpat sdikdv......dslmrisg riecesPnrhlydfvgnirl .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..............dghgtv plgadqillrgaqlrntqwv hGiVvytGhdtklmqNsts. pplKlsnveritnvqililf ciliamslvcsvgsaiwnrr h......sgkdwylnlnygg ..............asnfgl nfltfiilfnnliPISLlvt lkvvkftqayfInwDldmhy ep.................. .................... .................... .................... .................... ............tdtaamar tsnlnEeLGqvkyifSDKTG TLTcNvMqFkkctiagv.ay g................... .................... .................... .................... .................... .................... .................... ...................h vpepedygcspdewqnsqfg dektfsdssllenlqn..nh ptapiicefltmmavCHtav pere.gd............. .................... kiiYqAaSPDEgALVraakq lnfvftgRtpd......... .................... .................... .................... .................... ......sviidslgqe.... .eryelLnvleFtSaRKRMs vivrtpsg............ .................... .................... .................... .................... ......klrlycKGADtviy drlaetskyk.......... .................... .................... .................... .................... .................... .................... .................... .............eitlkhl eqfAteGLRTLcfavaeise sdfqewravyqrAstsvqn. Rllkleesy.eliEknLqLl GaTaiEDkLQdqVpetietL mkAdIkiWiLTGDKqETAin IghsckLlkknmgmivineg ...............sldgt retls............... .................... .................... .................... ...rhcttlgdalrkendfa liidGktlkyaltf...... .gvrqyFldlalsckaViCC RvsPlQKsevVemvkk.qvk vvtlAIGDGaNDVsMIQtAh vGvGIsGnEGlQAanssDys iaqFkyLknLLmiHGawnYn Rvskcilycfyknivlyiie iwfafvngfsgqilferwci glynvmfTamPpltlgifer scrkenmlkyPeLYktsqn. aldfntkvFwvhclnglfhs vilfwfplkalqygtafgn. .gktsdylllgnfvytfvvi tvclkagletsyWt...... wfshiaiwgSialwvvffgi ysslwpaip.mapdmsg... eaamlfssgvfwmgllfipv asllldvvykvikrtafktl vdevqeleaksqdpgavvlg kslteraqllknvfkknhvn lyrseslqqnllhgyafsqd engivsqseviraydttkqr pdew................ .................... .................... .................... .................... .................... .................... .................... .....
   -   Q9U280    Caenorhabditis elegans      Y49E10.11      .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .mpteardnnrhihlgkvrd phhqhaqrfcsNristckYn gfsFlPrflyeQFr.rynNi fFlaiallqqipdvs.ptgr yttavPfliilsvsalkeif eDvkrrrsDnkvNafsveil vdgh................ .................... .................... .................... .................... ...................w iekqwkdvsvGdfiridnds lfPADlllLasseqqgmayi eTsnLDGETnlKikqaldit stmtsp......eklsqfes eitcepPsrhvnefngniei .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............ngvar hfgidqlllrgarlkntawi fGaViytGhdskllmNskr. aplKsgtidvqtnyriiflf fvlvalalisatgseiwrgn n......ipqawylsflehd p.............kgsflw gvltffilynnliPISLqvt levvrffqaiyInnDiemyd vn.................. .................... .................... .................... .................... ............sdscaiar tsnlnEeLGqvkfimSDKTG TLTrNvMkFkrlsigsr.ny g................... .................... .................... .................... .................... .................... .................... .................... ................nned de..fadasliedyrq..gd ehstsilevlkmmavCHtvv penk.dg............. .................... qliYqssSPDEaALVrgaas qsvsfhtRqpq......... .................... .................... .................... .................... ......kvicnvfged.... .etieiLdvidFtSdRKRMs vivrdgagg........... .................... .................... .................... .................... ......diklytKGADtvif erlehgkeqee......... .................... .................... .................... .................... .................... .................... .................... ...........aveyctehl edyAsfGyRTLcfsmrhlte qeysqwapeykkAilaidn. Raklladaa.eklErnmiLv GaTaiEDkLQewVpetiqaL maAdIrvWmLTGDKrETAin IahscaLchtntellivdkt ...............tyeet yqkle............... .................... .................... .................... ...qfvaraielekqekgfa mvidGksllhaltg...... .earkhFgdlalrchaVvCC RmsPmQKaevVemvrk.lak hvvlAIGDGaNDVaMIQaAn vGvGIsGeEGlQAasasDya iprFhfLrrLLlVHGawnhd Rsvkvilysfykniclyiie lwfamfsawsgqtiferwti gmfnvifTawPpvvlglfdh pvpaeqimkyPaLYasfqnr afsignfslwig..laivhs lslffltyatmehqvvwdn. .gltggwlmlgncaytfvva tvcfkallecdsWt...... wpvvvacigSiglwivfviv yslvfphiggigadmag... maaimmssytfwlallfipl atllwdlvikslftiamptp relavmynkrttsfngferl asswaayqgptkdgahvfan rfslrkriqptsttaashps atspppngyveksqlngkng khhrakspdygstelstwst rdeheveykiprgrkerssy tnrafiaednnvtsivvnde edgsgtsyssnvlenmrllt sslrgsttgstrsrtaseas lalaeqtrygfafsqdessa vaqtelirnvdstrekptgr .................... .....
  15   P39524    Saccharomyces cerevisiae    DRS2/yal026c   .................... ...........mnddretpp krkpgeddtlfdidflddtt shsgsrskvtnshangyyip pshvlpeetidldadddnie ndvhenlfmsnnhddqtswn anrfdsdayqpqslravkpp glfarfgnglknaftfkrkk gpesfemnhynavtnneldd nyldsrnkfnikilfnryil rknvgdaegngeprvihind slanssfgysdNhisttkYn fatFlPkflfqeFs.kyaNl fFlctsaiqqvphvs.ptnr yttigtllvvlivsamkeci eDikransDkelNnstaeif seahdd.............. .................... .................... .................... .................... ...................f vekrwidirvGdiirvksee piPADtiiLsssepeglcyi eTanLDGETnlKikqsrvet akfidv......ktlknmng kvvseqPnsslytyegtmtl .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............ndrqi plspdqmilrgatlrntawi fGlViftGhetkllrNata. tpiKrtavekiinrqiirlf tvlivlilissignvimsta d......akhlsylylegtn k.............aglffk dfltfwilfsnlvPISLfvt velikyyqafmIgsDldlyy ek.................. .................... .................... .................... .................... ............tdtptvvr tsslvEeLGqieyifSDKTG TLTrNiMeFkscsiagh.cy i................... .................... .................... .................... .................... .................... .................... .................... ......dkipedktatvedg ievgyrkfddlkkklndpsd edspiindfltllatCHtvi pefqsdg............. .................... sikYqAaSPDEgALVqggad lgykfiiRkgns........ .................... .................... .................... .................... .....vtvlleetgee.... .keyqlLniceFnStRKRMs aifrfpdg............ .................... .................... .................... .................... ......siklfcKGADtvil erlddeanqy.......... .................... .................... .................... .................... .................... .................... .................... ............veatmrhl edyAseGLRTLclamrdise geyeewnsiyneAattldn. Raekldeaa.nliEknLiLi GaTaiEDkLQdgVpetihtL qeAgIkiWvLTGDrqETAin IgmscrLlsedmnlliinee ...............trddt ernll............... .................... .................... .................... ekinalnehqlsthdmksla lvidGkslgfalep...... .eledylltvaklckaViCC RvsPlQKalvVkmvkr.kss slllAIasGaNDVsMIQaAh vGvGIsGmEGmQAarsaDia lgqFkfLkkLLlVHGswsYq Risvailysfykntalymtq fwyvfanafsgqsimeswtm sfynlffTvwPpfvigvfdq fvssrlleryPqLYklgqk. gqffsvyiFwgwiingffhs aivfigtiliyrygfalnmh .geladhwswgvtvyttsvi ivlgkaalvtnqWt...... kftliaipgSllfwliffpi yasifphan.isreyyg... vvkhtygsgvfwltlivlpi falvrdflwkyykrmyepet yhviqemqkynisdsrphvq qfqnairkvrqvqrmkkqrg fafsqaeeggqekivrmydt tqkrgkygelqdasanpfnd nnglgsndfesaepfienpf adgnqnsnrfsssrddisfd i................... .................... .................... .................... .................... .................... .....
   -   O43520    Homo sapiens                ATP8B1/FIC1    .................... .................... .................... .................... .................... .................... .................mst erdsettfdedsqpndevvp ysddetedelddqgsavepe qnrvnreaeenrepfrkect wqvkandrkyheqphfmntk flcikeskyanNaiktykYn aftFiPmnlfeQFk.raaNl yFlallilqavpqis.tlaw yttlvPllvvlgvtaikdlv dDvarhkmDkeiNnrtcevi kdgrfk.............. .................... .................... .................... .................... .................... .vakwkeiqvGdvirlkknd fvPADillLsssepnslcyv eTaeLDGETnlKfkmsleit dqylq.....redtlatfdg fieceePnnrldkftgtlfw .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............rntsf pldadkillrgcvirntdfc hGlVifaGadtkimkNsgk. trfKrtkidylmnymvytif vvlillsaglaighayweaq v......gnsswylydgedd tpsyr............gfl ifwgyiivlntmvPISLyvs vevirlgqshfInwDlqmyy ae.................. .................... .................... .................... .................... ............kdtpakar tttlnEqLGqihyifSDKTG TLTqNiMtFkkccingq.iy g................... .................... .................... .................... .................... .................... .................... ...................d hrdasqhnhnkieqvdfswn tyadgklafydhylieqiqs gkepevrqfffllavCHtvm vdrtdg.............. .................... qlnYqAaSPDEgALVnaarn fgfaflaRtqn......... .................... .................... .................... .................... ......titiselgte.... .rtynvLaildFnSdRKRMs iivrtpeg............ .................... .................... .................... .................... ......niklycKGADtviy erlhrmnp............ .................... .................... .................... .................... .................... .................... .................... ...........tkqetqdal difAnetLRTLclcykeiee keftewnkkfmaAsvastn. Rdealdkvy.eeiEkdLiLl GaTaiEDkLQdgVpetiskL akAdIkiWvLTGDKkETAen IgfaceLltedtticygedi ns.............llhar menqr............... .............nrggvya kfappvqesffppggnrali itgswlneillekktkrnki lklkfprteeerrmrtqs.k rrleakkeq........... ..rqknFvdlacecsaViCC RvtPkQKamvVdlvkr.ykk aitlAIGDGaNDVnMIktAh iGvGIsGqEGmQAvmssDys faqFryLqrLLlVHGrwsYi Rmckflryffyknfaftlvh fwysffngysaqtayedwfi tlynvlyTslPvllmglldq dvsdklslrfPgLYivgqr. dllfnykrFfvsllhgvlts milffiplgaylqtvgq..d geapsdyqsfavtiasalvi tvnfqigldtsyWt...... fvnafsifgSialyfgimfd fhsag..ihvlfpsafqftg tasnalrqpyiwltiiltva vcllpvvairflsmtiwpse sdkiqkhrkrlkaeeqwqrr qqvfrrgvstrrsayafshq rgyadlissgrsirkkrspl daivadgtaeyrrtgds... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   Q9TXV2    Caenorhabditis elegans      H06H21.10      .................... .................... .................... .................... .................... .................... .................... .................... .................... .............mfswlpc csstsneknapterrlrand reynaqfkyadNviktskYn iltFiPqnlfeQFq.riaNf yFlvlmilqfipqis.sisw ystavPlvivlafsaikdgy dDaqrhisDrnvNgrksyvv rngslc.............. .................... .................... .................... .................... .................... .eedwsnvkvGdvirmmsnq fvaADlllLstsepygvcfi eTmeLDGETnlKnraaiact qemg......ddldgtrfdg eiicepPnnkldkfngkliw .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............nnhey gvnndnillrgcilkntrwc yGvVvfaGkdtklmmNsgk. tkfKrtsldrflnilivgiv lfliamclictilcavweyq t.....gryftiylpwddvv psgrq........ialiafl qffsyiillntvvPISLyvs veiirfihslwInyDtqmyy enge................ .................... .................... .................... .................... ............ksvpakah tttlnEeLGqvqyvfSDKTG TLTrNiMtFnkctingi.sy g................... .................... .................... .................... .................... .................... .................... ................diyd hkgevietndktksldfswn saseptfkffdknlvdatkr .qvpeidqfwrllalCHtvm perdkg.............. .................... qlvYqAqSPDEhALtsaarn fgyvfraRtpq......... .................... .................... .................... .................... ......sitievmgne.... .ethelLaildFnndRKRMs vivkgpdg............ .................... .................... .................... .................... ......kirlycKGADmmim qrihpstsqi.......... .................... .................... .................... .................... .................... .................... .................... ...........mrtstnthl adfAniGLRTLclgykd... .nyrlfqsrvkkAsaamqd. Resavdaly.eeiEkdLiLi GaTaiEDkLQdgVpeaiarL seAnIkiWvLTGDKtETAin IayscrLltdetkeivvvdg qt.............dteve vqlkd............... .................trn tfeqilalpsplggkpriei etiheeseaissarsmdrni vtpdlksaemaehesggv.a lvinGdslafalgp...... .rlertFlevacmcnaViCC RvtPlQKaqvVdlvkr.nkk avtlsIGDGaNDVsMIktAh iGvGIsGqEGmQAvlasDys igqFkyLerLLlVHGrwsYi Rmakflryffyknfaftltn fwysffcgysaqtvfdavli acynlffTalPvlamgsldq dvddhyslryPkLYlpgqf. nlffnmriFiysvlhgmfss lviffipygafynaaaa..s gkdlddysalafttftalvv vvtgqiafdtsyWt...... aishfviwgSlvlyflvcfl lyewlpvswivktsssisyg vafrtmvtphfwfsilmvsv vlllpvmlnrffwldthpsf adrlrirkkmgkkpsakddk ktafkrtaatrrsvrgslrs gyafshsqgfgelilkgklf knvenlrgknnsnakihpts ddlqpmlissvpddsqgass inamhlpmgtrpqnvphtln vntddwsqssdfrpayakep splqgtvirgdgrshrnhvy sretqveeqpdvitrl.... .................... .................... .................... .....
   -   O60423    Homo sapiens                ATP8B3         .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ......dlcvGdvvclrkdn ivPADmllLastepsslcyv eTvdiDGETnlKfrqalmvt hkela.....tikkmasfqg tvtceaPnsrmhhfvgclew .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............ndkky sldignlllrgcrirntdtc yGlViyaGfdtkimkNcgk. ihlKrtkldllmnklvvvif isvvlvclvlafgfgfsvke f......kdhhyylsgvhgs svaae............sff vfwsflillsvtiPmSmfil sefiylgnsvfIdwDvqmyy kp.................. .................... .................... .................... .................... ............qdvpakar stslndhLGqveyifSDKTG TLTqNiltFnkccisgr.vy g................... .................... .................... .................... .................... .................... .................... .................... ....agpcprhpqenpylwn kfadgkllfhnaallhlvrt ngdeavrefwrllaiCHtvm vresph.............. .................... qllYqAaSPDEgALVtaarn fgyvflsRtqd......... .................... .................... .................... .................... ......tvtimelgee.... .rvyqvLaimdFnStRKRMs vlvrkpeg............ .................... .................... .................... .................... ......aiclytKGADtvif erlhrrga............ .................... .................... .................... .................... .................... .................... .................... ...........mefateeal aafAqetLRTLclayrevae diyedwqqrhqeAslllqn. Raqalqqvy.nemEqdLrLl GaTaiEDrLQdgVpetikcL kksnIkiWvLTGDKqETAvn IgfaceLlsenmlileekei sr.............ilety wensnnlltreslsqvklal vingdfl............. .....dkllvslrkeprala qnvnmdeawqelgqsrrdfl yarrlsllcrrfglplaa.p paqdsrarrssev....... .lqeraFvdlaskcqaViCC RvtPkQKaliValvkk.yhq vvtlAIGDGaNDinMIktAd vGvGlaGqEGmQAvqnsDfv lgqFcfLqrLLlVHGrwsYv Rickflryffyksmasmmvq vwfacyngftgqplyegwfl alfnllystlPvlyiglfeq dvsaeqslekPeLYvvgqk. delfnywvFvqaiahgvtts lvnffmtlwisrdtag.... pasfsdhqsfavvvalscll sitmeviliikyWt...... alcvatillSlgfyaimttt tqsfw..lfrmptsa..... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   O94296    Schizosaccharomyces pombe   SPBC887.12     .................... .................... .................... ............mardvdnk qnakrisrdededefagesm vgrtldnpflgedefedifg sesqyisssgqnstnpflad triensplgseskanqlnkq gtnvnhieiplrdfndptqp esflpppkntftsrikkikn lfkkekkqvkpedlgprqii lndysanhflhNavstckYs aftFlPkflkeQFs.kyaNl fFlftavvqqipgit.pvnr yttigPmlivlsvsgikeim eDikrkkqDqelNes..pcy vlqgtg.............. .................... .................... .................... .................... ...................f vekqwkdvvvGdivkivset ffPADlvlLsssepeglcyi eTanLDGETnlKikqalpet agllkp......velgqlsg evkseqPnnnlytfdatlkl lp.................. .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............sdrel plspdqlllrgaqlrntpwv yGiVvftGhesklmkNtte. tpiKrtsvekqvnsqilfll cifvflcfasslgalihrsv y......gsalsyvkytsnr ..............agmffk glltfwilysnlvPISLfvt felvryiqaqlIssDldmyn ee.................. .................... .................... .................... .................... ............tdtpaacr tsslvEeLGqvgyifSDKTG TLTrNqMeFrqctiagv.ay a................... .................... .................... .................... .................... .................... .................... .................... ......dvipedrqftsedl dsdmyiydfdtlkenlkhse nas.lihqfllvlsiCHtvi peydest............. ...................n sikYqAsSPDEgALVkgaas igykflaRkphl........ .................... .................... .................... .................... .....vtvsifgkdes.... ...yelLhiceFnStRKRMs ivfrcpdg............ .................... .................... .................... .................... ......kirlyvKGADtvim erlasdnp............ .................... .................... .................... .................... .................... .................... .................... ...........ylqttihhl edyAtvGLRTLciamrevpe deyqrwstvfetAasslvd. Raqklmdaa.eeiEkdLiLl GaTaiEDrLQdgVpdtistL qtAgIkiWvLTGDrqETAin IgmsckLidedmglvivnee ...............tkeat aesvm............... .................... .................... .................... aklssiyrneattgnvesma lvidGvsltyaldf...... .slerrFfelaslcraViCC RvsPlQKaliVkmvkr.ntg evllAIGDGaNDVpMIQaAh vGvGIsGmEGlQAvrssDfs isqFcyLkkLLlVHGswcYq Rlsklilysfyknialymtq fwyafcnafsgqvifeswsi slynvlfTvlPpvvigifdq fvsagqlfqyPqLYqlgqr. seffnlkrFwswitngfyhs lllflcsiavfyydgpnkd. .glasghwvwgttlyaaila tvlgkaalisnhWt...... qytviatlgSfllwivfmpi yavaapaig.fskeyyg... iiphlygnlkfwasllvlpt ialmrdfvwkyssrmyypee yhyvqeiqkynvtdyrpriv gfhkairkirqmqrmrkqrg yafsqgeedqsrildaydtt htrgaygemr.......... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   Q9SX33    Arabidopsis thaliana        ALA9/F24J5.6   .................... .................... .................... .................... .................... .................... .................... .................... ..........mvgggtkrrr rrlqlsklytltcaqacfkq dhsqiggpgfsrvvycnepd speadsrnysdNyvrttkYt latFlPkslfeQFr.rvaNf yFlvtgvlaftpla..pyta ssaivPllfvigatmvkegv eDwrrqkqDnevNnrk.vkv hrgdgs.............. .................... .................... .................... .................... ...................f dakewktlsiGdivkvekne ffPADlvlLsssyedaicyv eTmnLDGETnlKvkqglevt sslrde......fnfkgfea fvkcedPnanlysfvgtmel .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............kgaky plspqqlllrdsklrntdfi fGaViftGhdtkviqNstd. ppsKrsmiekkmdkiiylmf fmvitmafigsvifgvttrd d..lkdgvmkrwylrpdsss iffdpkra......pvaaiy hfltavmlysyfiPISLyvs ieivkvlqsifInqDihmyy ee.................. .................... .................... .................... .................... ............adkparar tsnlnEeLGqvdtilSDKTG TLTcNsMeFikcsvagt.ay g................... .................... .................... .................... .................... .................... .................... rgvtevemamgrrkggplvf qsdendidmeyskeaitees tvkgfnfrderimngnwvte thadviqkffrllavCHtvi pevdedt............. ...................e kisYeAeSPDEaAfViaare lgfeffnRtqtt........ .................... .................... .................... .................... ......isvreldlvsgkrv erlykvLnvleFnStRKRMs vivqeedg............ .................... .................... .................... .................... ......kllllcKGADnvmf erlskngre........... .................... .................... .................... .................... .................... .................... .................... ...........feeetrdhv neyAdaGLRTLilayrelde keykvfneriseAkssvsad Reslieevt.ekiEkdLiLl GaTavEDkLQngVpdcidkL aqAgIkiWvLTGDKmETAin IgfacsLlrqdmkqiiinle tpeiqslektgekdviakas kenvls.............. .................... .................... .................... ..qiingktqlkysggnafa liidGkslayaldd...... .dikhiFlelavscasViCC RssPkQKalvtrlvks.gng kttlAIGDGaNDVgMlQeAd iGvGIsGvEGmQAvmssDia iaqFryLerLLlVHGhwcYr Ristmicyffyknitfgftl flyetyttfsstpayndwfl slynvffsslPvialgvfdq dvsaryclkfPlLYqegvq. nvlfswrrilgwmfngfysa viifflcksslqsqafnhd. .gktpgreilggtmytcivw vvnlqmalaisyft...... liqhiviwsSivvwyffitv ygelpsris..tgaykv... fvealapslsywlitlfvvv atlmpyfiysalqmsffpmy hgmiqwlryegqcndpeycd ivrqrsirpttvgftarlea kkrsvrisepas........ .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   Q9SLK6    Arabidopsis thaliana        ALA6/F20D21.10 .................... .................... .................... .................... .................... .................... .................... .................... ..........marrrirsri rkshfytfrclrpktlddqg phvingpgytrivhcnqphl hlatkliryrsNyvsttrYn lltFlPkclyeQFh.rvaNf yFlvaailsvfpls..pfnk wsmiaPlvfvvglsmgkeal eDwrrfmqDvevNsrk.asv hkgsgd.............. .................... .................... .................... .................... ...................f grrtwkrirvGdivrvekde ffPADlllLsssyedgicyv eTmnLDGETnlKvkrcldat lalekd......esfqnfsg tikcedPnpnlytfvgnlec .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............dgqvy pldpnqillrdsklrntayv yGvVvftGhdtkvmqNstk. spsKrsriekrmdyiiytlf allltvsfisslgfavmtkl l......maewwylrpdkpe sltnptnp......lyawvv hlitalllygyliPISLyvs ievvkvlqahfInqDlqlyd se.................. .................... .................... .................... .................... ............sgtpaqar tsnlnEeLGqvdtilSDKTG TLTcNqMdFlkcsiagt.sy g................... .................... .................... .................... .................... .............vraseve laaakqmamdleekgeevan lsmnkgrtqryaklasktss dfeletvvtasdekdqkqnt gvkgfsfednrlmnenwlne pnsddilmffrilavCHtai pevdedt............. ...................g mctYeAeSPDEvAflvasre fgfeftkRtqss........ .................... .................... .................... .................... ......vfiaerfssse... ...ykiLnlldFtSkRKRMs aivrdeeg............ .................... .................... .................... .................... ......qilllcKGADsiif erlsksgke........... .................... .................... .................... .................... .................... .................... .................... ...........ylgatskhl nvygeaGLRTLalgyrklde teyaawnsefhkAktsvgad Rdemlekvs.dmmEkeLiLv GaTavEDkLQkgVpqcidnL aqAglkiWvLTGDKmETAin IgyacsLlrq.......... .................... .................... .................... .................... .................... .................afa liidGktltyalkd...... .dvkyqFlalavdcasViCC RvsPkQKalvtrlake.gtg kttlAIGDGaNDVgMIQeAd iGvGIsGvEGmQAvmasDfs iaqFrfLerLLvVHGhwcYk Riaqmicyffyknitfgltl fyfecftgfsgqsiyndsyl llfnvvlTslPvislgvfeq dvpsdvclqfPaLYqqgpk. nlffdwyrilgwmgngvyas iviftlnlgifhvqsfrsd. .gqtadmnamgtamftciiw avnvqialtmshft...... wiqhvmiwgSigawyvflal ygmlpvkls..gnifhm... lveilapapifwltsllvia attlpylfhisyqrsvnpld hhiiqeikhfridvedermw krekskarektkigftarvd akirqlrgrlqrkhsvlsvm sgtssndtpssnsq...... .................... .................... .................... .................... .................... .................... .................... .................... .....
   -   Q9SAF5    Arabidopsis thaliana        ALA11/F3F19.24 .................... .................... .................... .................... .................... .................... .................... .................... ..............mtkcrr rrlhlsniyafkgrksnfqe dhshiggpgfsrvvycnepn spaaerrnyvgNyvrstkYt lasFiPkslfeQFr.rvaNf yFlvtgvlsltals..pysp isallPltfviaasmvkeai eDwgrkkqDiemNnrk.vkv hdgngi.............. .................... .................... .................... .................... ...................f rregwrdlkvGnivrvekde ffPADlllLsssyedsicyv eTmnLDGETnlKvkqgleat ssalhed.....sdfkelka vvkcedPnadlytfvgtlhf .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............eeqrl plsitqlllrdsklrnteyi yGvVvftGhdtkviqNstd. ppsKrsrierkmdkiiylmf gvvflmsfigsivfgietre drvrnggrterwylrpdnad iffdpdra......pmaavy hfftavmlysyfiPISLyvs ieivkvlqslfInnDilmyy ee.................. .................... .................... .................... .................... ............ndkpahar tsnlnEeLGmvdtilSDKTG TLTcNsMeFikcsiagt.ay g................... .................... .................... .................... .................... .................... .................... .......rgiteversmamr sngsslvgddldvvvdqsgp kikgfnfldervmkgnwvkq rdaavlqkffrllavCHtai petdeat............. ...................g svsYeAeSPDEaAfVvaare fgfeffsRtqng........ .................... .................... .................... .................... ......isfreldlasgktv ervyrlLnvleFnSaRKRMs vivrdedg............ .................... .................... .................... .................... ......rllllsKGADnvmf erlakngrk........... .................... .................... .................... .................... .................... .................... .................... ...........feektrehv neyAdaGLRTLilayrevde neyiefsknfneAknsvtad Reslideit.eqmErdLiLl GaTavEDkLQngVpdcidkL aqAgIkiWvLTGDKmETAin IgfacsLlrqemkqiiinle tphikalekagekdaiehas resvvn.............. .................... .................... ..................qm eegkalltasssassheafa liidGksltyaled...... .dfkkkFldlatgcasViCC RssPkQKalvtrlvks.gtg kttlAIGDGaNDVgMlQeAd iGvGIsGvEGmQAvmssDia iaqFryLerLLlVHGhwcYs Rissmicyffyknitfgvtv flyeaytsfsaqpayndwfl slfnvffsslPvialgvfdq dvsarycykfPlLYqegvq. nllfswkriigwmfngvfta laifflckeslkhqlynpn. .gktagreilggtmytcvvw vvnlqmalaisyft...... wlqhiviwgSvafwyiflmi ygaitpsfs..tdaykv... fiealapapsywlttlfvmf falipffvfksvqmrffpgy hqmiqwiryeghsndpefve mvrqrsirpttvgftarraa svrrsgrfhdqlnknfiaf. .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
  16   Q09891    Schizosaccharomyces pombe   SPAC24B11.12c  .................... .................... .................... .................... .................... .................... .................... ....mesveekskqrrwlpn fkalrlkvyrladrlnipla daarveleeydgsdpqslrg lqklprtlyfglplpdseld dtgeakrwfprNkirtakYt pidFiPkniflQFq.nvaNl fFlflvilqsisifgeqvnp glaavPlivvvgitavkdai eDfrrtmlDihlNntptlrl shyqnpnirteyisyfrrfk krisalfrvflakqeekkra krlndavpledmagsesrps ydsifresfeakrsfedsk. .gkvplsaldgtatilqsrp ....mdiidyeaeatgechf kktywkdvrvGdfvkvmdnd eiPADiviinssdpegicyi eTknLDGETnlKmrhaltcg knvvde......ascercrf wiesepPhanlyeyngacks .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...fvhseaggsdtsqtvse pisldsmllrgcvlrntkwv iGvVvftGddtkimlNsga. pplKrsritrnlnwnvylnf iilfsmcfvcavvegiawrg h.......srssyyfefgsi g..........gspakdgvv tfftgvilfqnlvPISLyis ieivktiqaifIyfDkdmyy kk.................. .................... .................... .................... .................... ............lkyactpk swnisddLGqveyifSDKTG TLTqNvMeFkkctingv.ay gea................. .................... .................... .................... .................... .................... ...........fteamagma kregkdteeltlqkqsfier drmqmisqmrnmhdnkylvd dnltfissqfvhdlagkage eqslacyefflalalCHsvv adrv.gd............. .................... rivYkAqSPDEaALVgtard vgfvfldqrrd......... .................... .................... .................... .................... ......imvtralget.... .qrfklmdtieFsSaRKRMs vivkgpdn............ .................... .................... .................... .................... ......ryvlicKGADsiif erlepneqve.......... .................... .................... .................... .................... .................... .................... .................... ...........lrkttsehl rifAleGLRTLciakrelte eeyyewkekydiAasaien. Reeqieeva.dliEshLtLl GgTaiEDrLQegVpdsialL aqAgIklWvLTGDKmETAin IgfscnLldagmdmikf... ...............dvdqe vstp................ .................... ..................el eviladylyryfgls....g sveeleaakkdhdtpsgsha lvidGsvlkrvldg...... .pmrtkFlllckrckaVlCC RvsPaQKadvVqlvre.sle vmtlAIGDGaNDVaMIQkAd iGvGIvGeEGraAamsaDya igqFrfLskLvlVHGrwdYn Rvaemvnnffyksvvwtftl fwyqiynnfdanylfdytyv mlfnlifsslPvivmgvydq dvnadlslriPqLYkrgil. qlnsarkiFigymldgfyqs vicfffsflvinnvttaaqn grdtmavqdlgvyvaaptim vvdtyvilnqsnWd...... vfsiglwalScltfwfwtgv ysqslytyefyks....... .asrifrtpnfwavlcgtiv sclfpkflfmttqklfwpyd vdiiresyrtkrlheldeee eienaeqspdwasstlqvpf nasssslatpkkeplrldtn sltltssmprsftpsytpsf legspvfsdeilnrgeymph rgsissseqplrp....... .................... .................... .................... .................... .................... .................... .....
   -   O36028    Schizosaccharomyces pombe   SPAC4F10.16c   .................... .................... .................... .................... .................... .mpslinfdaisslksslhg lsicafnhlhhvpqhngsla hegptnqtdyssrhhesqfs qeahaeqrsrddeeansfeg scnnsdqswtsrvtskknea gtesgdasvrriyvtsipee hrhlpsqwfpsNkirttkYt pvsFiPknlwnQFk.niaNa fFlfvtllqciplfc.pehl glsfiPlsvillttaikdgi eDyrrcvlDkkfNntltwkl vgfnnanalgehiglwrklk kfishtvadmsyclknsgis sglatltvdnishrhslesd saftlssvsqdsleiheign sgpsnsfsviqeqstgssn. .................akf ervcrksllvGdivkvlade aiPADlliLstensngvcyv eTknLDGETnlKdkyalcst kccks......eyrcsaasf wveceqPhadlyslngvvka .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .pgavqspsestngrkihee pfsisnvllcgctlrnskwv iGlVlytGsetriqkNrgl. tpsKrsritrdlnwtiilnf lllfamclfsgvlrsiysaq n.....nsarvfelsknsn. ............tapahgii siftslilfqnlvPISLyit mdivrsiqsyfIfsDremyd ek.................. .................... .................... .................... .................... ............ldcpcspk swnisddLGqieyifSDKTG TLTqNiMsFkkcsingi.ry g................... .................... .................... .................... .................... .................... ................kshn edtcikkrrnlnynenlsck vdldkkkmletlslsdspnp esitfisskfvdhlqsneny iqteacfeffkalalCHsvv tdvqdet............. .................... .liYnAqSPDEeALVkvard fgftllntknr......... .................... .................... .................... .................... ......rytirirgen.... .knfrvLdiipFtStRKRMs viirdedg............ .................... .................... .................... .................... ......iihlicKGADtvif prlssgqnn........... .................... .................... .................... .................... .................... .................... .................... ...........iiektkkhl asfsseGfRTLciarrtidk qdylewkvnfneAnsaihe. Rnekvskvs.emiEqeLeLl GgTaiEDkLQenVpetialL aiAgIklWvLTGDKvETAin IgyscnLldpnmtifridan sf.............galee veafirn............. .................... .................... ..........tlcfnfgymg tdeefrfllkdhsppspkha ividGdalnfvlse...... .qvsflFlmlckqcktVlCC RvsPsQKaavValvkk.sln vvtlAIGDGaNDVsMIQeAd vGvGIkGvEGqaAsmsaDya igqFsfLgrLLlVHGrwdYk Rmsqmisfffyknviwtfil fwyqfynefdgnyifdytyv mlfnllfTslPviiagcfdq dvdasvsmknPsLYqrgil. glewngkrFwsymldgiyqs lvcfgvalfvfkfgdfvswt grnieciediglfissptif vinifilmnqerln...... lislitwmfSigvfwiwtfi ysevgpsyafhks....... .asrtcqtfgfwcvtvltia lcllprfsyiclqklfyprd idllrrrlcaksddetssss sfatdiemceqcndplsskk nsgivtsvsfddsnk..... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
  17   Q12675    Saccharomyces cerevisiae    ydr093w        msspskptspfvddiehesg sasnglssmspfddsfqfek pssahgnievaktggsvlkr qskpmkdistpdlskvtfdg iddysndndindddelngkk teihehenevdddlhsfqat pmpntggfedveldnnegsn ndsqadhklkrvrfgtrrnk sgridinrsktlkwakknfh naidefstkedslensalqn rsdelrtvyynlplpedmld edglplavyprNkirttkYt pltFfPknilfQFh.nfaNi yFlillilgafqifg.vtnp gfasvPliviviitaikdgi eDsrrtvlDlevNntrthil sgvknenvavdnvslwrrfk kantralikifeyfsenlta agrekklqkkreelrrkrns rsfgprgsldsigsyrmsad fgrpsldyenlnqtmsqanr yndgenlvdrtlqpnpecrf akdywknvkvGdivrvhnnd eiPADmilLstsdvdgacyv eTknLDGETnlKvrqslkcs kiikss......rditrtkf wvesegPhanlysyqgnfkw .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .........qdtqngnirne pvninnlllrgctlrntkwa mGmViftGddtkimiNagv. tptKksrisrelnfsvilnf vllfilcftagivngvyykq kpr......srdyfefgtig ...........gsastngfv sfwvavilyqslvPISLyis veiiktaqaifIytDvllyn ak.................. .................... .................... .................... .................... ............ldypctpk swnisddLGqieyifSDKTG TLTqNvMeFkkctingv.sy gra................. .................... .................... .................... .................... .................... ...........ytealaglr krqgvdvesegrrekeeiak dretmidelrsmsdntqfcp edltfvskeivedlkgssgd hqqkccehfllalalCHsvl vepnkdd............. ..................pk kldikAqSPDEsALVstarq lgysfvgssks......... .................... .................... .................... .................... ......gliveiqgvq.... .kefqvLnvleFnSsRKRMs ciikipgstpk......... .................... .................... .................... .................... ...depkallicKGADsviy srldrtqndat......... .................... .................... .................... .................... .................... .................... .................... ...........llektalhl eeyAteGLRTLclaqreltw seyerwvktydvAaasvtn. Reeeldkvt.dviEreLiLl GgTaiEDrLQdgVpdsialL aeAgIklWvLTGDKvETAin Igfscnvlnndmellvvkas ge.............dveef gsdpi............... .................... .................qvv nnlvtkylrekfgms....g seeelkeakrehglpqgnfa viidGdalkvalnge..... .emrrkFlllcknckaVlCC RvsPaQKaavVklvkk.tld vmtlAIGDGsNDVaMIQsAd vGvGIaGeEGrQAvmcsDya igqFryvtrLvlVHGkwcYk Rlaemipqffyknviftlsl fwygiynnfdgsylfeytyl tfynlafTsvPvillavldq dvsdtvsmlvPqLYrvgil. rkewnqtkFlwymldgvyqs vicfffpylayhknmvvten glgldhryfvgvfvtaiavt scnfyvfmeqyrWd...... wfcglficlSlavfygwtgi wtsssssnefykg....... .aarvfaqpaywavlfvgvl fcllprftidcirkifypkd ieivremwlrgdfdlypqgy dptdpsrprineirpltdfk episldthfdgvshsqetiv .teeipmsilngeqgsrkgy rvsttlerrdqlspvtttnn lprrsmasargnklrtsldr treemlanhqldtrysvera rasldlpginhaetllsqrs rdr................. .................... .................... .................... .....
  18   P32660    Saccharomyces cerevisiae    yer166w        .................... ...............msgtf hgdghapmspfedtfqfedn ssnedthiapthfddgatsn kysrpqvsfndetpknkred aeeftfnddteydnhsfqpt pklnngsgtfddveldndsg ephtnydgmkrfrmgtkrnk kgnpimgrsktlkwarknip npfedf.tkddi.dpgai.n raqelrtvyynmplpkdmid eegnpimqyprNkirttkYt pltFlPknilfQFh.nfaNv yFlvliilgafqifg.vtnp glsavPlvviviitaikdai eDsrrtvlDlevNntkthil egvenenvstdnislwrrfk kansrllfkfiqyckehlte egkkkrmqrkrhelrvqktv gtsgprssldsidsyrvsad ygrpsldydnleqgagean. ......ivdrslpprtdckf aknywkgvkvGdivrihnnd eiPADiilLstsdtdgacyv eTknLDGETnlKvrqslkct ntirts......kdiartkf wiesegPhsnlytyqgnmkw .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .........rnladgeirne pitinnvllrgctlrntkwa mGvVmftGgdtkimlNsgi. tptKksrisrelnfsvvinf vllfilcfvsgiangvyydk kgr.....srfsyefgtia. ...........gsaatngfv sfwvavilyqslvPISLyis veiiktaqaafIygDvllyn ak.................. .................... .................... .................... .................... ............ldypctpk swnisddLGqveyifSDKTG TLTqNvMeFkkctingv.sy gra................. .................... .................... .................... .................... .................... ...........ytealaglr krqgidvetegrrekaeiak drdtmidelralsgnsqfyp eevtfvskefvrdlkgasge vqqrccehfmlalalCHsvl veanpdn............. ..................pk kldlkAqSPDEaALVatard vgfsfvgktkk......... .................... .................... .................... .................... ......gliiemqgiq.... .kefeiLnileFnSsRKRMs civkipglnpg......... .................... .................... .................... .................... ...deprallicKGADsiiy srlsrqsgsnsea....... .................... .................... .................... .................... .................... .................... .................... ...........ilektalhl eqyAteGLRTLciaqrelsw seyekwnekydiAaaslan. Redelevva.dsiEreLiLl GgTaiEDrLQdgVpdcielL aeAgIklWvLTGDKvETAin IgfscnLlnnemellviktt gd.............dvkef gseps............... .................... .................eiv dallskylkeyfnlt....g seeeifeakkdhefpkgnya ividGdalklalyge..... .dirrkFlllckncraVlCC RvsPsQKaavVklvkd.sld vmtlAIGDGsNDVaMIQsAd vGiGIaGeEGrQAvmcsDya igqFryLarLvlVHGrwsYk Rlaemipeffyknmifalal fwygiyndfdgsylyeytym mfynlafTslPviflgildq dvndtislvvPqLYrvgil. rkewnqrkFlwymldglyqs iicfffpylvyhknmivtsn glgldhryfvgvyvttiavi scntyvllhqyrWd...... wfsglfialSclvvfawtgi wssaiasreffka....... .aariygapsfwavffvavl fcllprftydsfqkffyptd veivremwqhghfdhyppgy dptdpnrpkvtkagqhgeki iegialsdnlggsnysrdsv vteeipmtfmhgedgspsgy qkqetwmtspketqdllqsp qfqqaqtfgrgpstnvrssl drtreqmiatnqldnrysve rartsldlpgvtnaasligt qqnn................ .................... .................... .................... .....
   -   P98204    Arabidopsis thaliana        ALA1/MUG13.22  .................... .................... .................... .................... .................... .................... .................... .....mdprksidkpphhdp ilgvssrwsvsskdnkevtf gdlgskrirhgsagadseml smsqkeikdedarliyindp drtnerfeftgNsiktakYs vftFlPrnlfeQFh.rvayi yFlviavlnqlpqla.vfgr gasimPlafvllvsaikday eDfrrhrsDrveNnrlalvf edhqfr.............. .................... .................... .................... .................... .................... .ekkwkhirvGevikvqsnq tlPcDmvlLatsdptgvvyv qTtnLDGEsnlKtryakqet llkaad........mesfng fikcekPnrniygfqanmei .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ...............dgrrl slgpsniilrgcelkntawa lGvVvyaGgetkamlNnsg. apsKrsrletrmnleiills lflivlctiaaataavwlrt h..rddldtilfyrrkdyse rp..ggknykyygwgweiff tffmavivyqimiPISLyis melvrigqayfmtnDdqmyd es.................. .................... .................... .................... .................... ............sdssfqcr alninEdLGqikylfSDKTG TLTdNkMeFqcaciegv.dy s................... .................... .................... .................... .................... .................... .................... ................drep adsehpgysiegvdgiilkp kmrvrvdpvllqltktgkat eeakranefflslaaCntiv pivsntsdp........... .................nvk lvdYqgeSPDEqALVyaaaa ygfllieRtsg......... .................... .................... .................... .................... ......hivinvrget.... .qrfnvLglheFdSdRKRMs vilgcpdms........... .................... .................... .................... .................... .......vklfvKGADssmf gvmdesygg........... .................... .................... .................... .................... .................... .................... .................... ...........vihetkiql hayssdGLRTLvvgmrelnd sefeqwhssfeaAstalig. Ragllrkva.gniEtnLriv GaTaiEDkLQrgVpeaiesL riAgIkvWvLTGDKqETAis IgfssrLltrnmrqivinsn ...............sldsc rrsle............... .................... .................... .................... ....eanasiasndesdnva liidGtsliyvldn...... .dledvlfqvackcsailCC RvaPfQKagiValvkn.rts dmtlAIGDGaNDVsMIQmAd vGvGIsGqEGrQAvmasDfa mgqFrfLvpLLlVHGhwnYq Rmgymilynfyrnavfvlil fwyvlftcytlttaitewss vlysviyTaiPtiiigildk dlgrqtlldhPqLYgvgqr. aegysttlFwytmidtiwqs aaiffipmfaywgst..... ....idtsslgdlwtiaavv vvnlhlamdvirWn...... withaaiwgSivaacicviv idviptlpg.........yw aifqvgktwmfwfcllaivv tsllprfaikflveyyrpsd vriareaeklgtfresqpvg vemnliqdpprr........ .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
PartialP98196    Homo sapiens                ATP11A         .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ..........qrnlflkaft dflafmvlfnyiiPvSmyvt vemqkflgsyfItwDedmfd ee.................. .................... .................... .................... .................... ............tgegplvn tsdlnEeLGqveyiftDKTG TLTeNnMeFkecciegh.vy vp.................. .................... .................... .................... .................... .................... .................... .................... ................hvic ngqvlpessgidmidsspsv ngrereelffralclCHtvq vkdddsvdgprkspdggk.. .................... scvYissSPDEvALVegvqr lgftylrlkdn......... .................... .................... .................... .................... ......ymeilnrenh.... ierfelLeilsFdSvRrRMs vivksatg............ .................... .................... .................... .................... ......eiylfcKGADssif prvieg.............. .................... .................... .................... .................... .................... .................... .................... ...........kvdqirarv ernAveGLRTLcvaykrliq eeyegickllqaAkvalqd. Rekklaeay.eqiEkdLtLl GaTavEDrLQekaadtieaL qkAgIkvWvLTGDKmETAaa tcyackLfrrntqllelttk rieeqs..lhdvlfelsktv lrhsgsltrdnlsgls.... .................... .................... .................... .............admqdyg liidGaalslimkpredgss gnyrelFleicrscsaVlCC RmaPlQKaqiVklikfskeh pitlAIGDGaNDVsMIleAh vGiGviGkEGrQAarnsDya ipkFkhLkkmLlVHGhfyYi Riselvqyffyknvcfifpq flyqffcgfsqqtlydtayl tlynisfTslPillyslmeq hvgidvlkrdPtLYrdvak. nallrwrvFiywtllglfda lvfffgayfvfenttvts.. ngqifgnwtfgtlvftvmvf tvtlklaldthyWt...... winhfviwgSllfyvvfsll wggviwpflnyqrmyy.... vfiqmlssgpawlaivllvt isllpdvlkkvlcrqlwpta tervqtksqclsveqstifm lsqtssslsf.......... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... .....
Identical in 25 out of 35 sequences                         -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -----------N-----KY- ---F-P--L--QF-----N- -FL--------P-------- -----PL---------K--- -D--R---D---N------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ---------VGD-------- --PAD---L--S-------- -T--LDGET--K-------- -------------------- ----E-P--------G---- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------L-------N---- -G-V---G--T----N---- ---K--------N------- -------------------- -------------------- -------------------- -------L----IPISL-V- ----K------I--D----- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------R -----E-LG---Y--SDKTG TLT-N-M-F----------Y -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------A-CH--- -------------------- -------------------- ---Y-A-SPDE-ALV----- -G-----R------------ -------------------- -------------------- -------------------- -------------------- -------------------- ------L----F-S-RKRMS -IV----------------- -------------------- -------------------- -------------------- -------------------- ---------L--KGAD---- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ---A--GLRTL--A------ ------------A------- R------------E--L-L- G-T--ED-LQ--V---I--L --AGIK-W-LTGDK-ETA-- I--S--L------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- L-IDG--L---L-------- ------F--L---C--V-CC R--P-QKA--V--------- ---LAIGDG-NDV-MIQ-A- -G-GI-G-EG-QA----D-- I-QF--L--LLLVHG---Y- R---------YK-------- --------F----------- ---N---T--P-------D- D---------P-LY------ --------F----------- -------------------- -------------------- ------------W------- ---------S---------- -------------------- ----------FW-------- ----P------------P-- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -----
Identical in 28 out of 35 sequences                         -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -----------N------Y- ---F-P-----QF-----N- -F------------------ -----P-------------- -D------D---N------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ----------G--------- --PAD---L----------- -T--LDGET--K-------- -------------------- ------P------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -G-V---G-------N---- ---K---------------- -------------------- -------------------- -------------------- -------------PISL--- -----------I--D----- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -----E-LG------SDKTG TLT-N-M-F----------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ---------------CH--- -------------------- -------------------- ---Y-A-SPDE-ALV----- -------R------------ -------------------- -------------------- -------------------- -------------------- -------------------- ------L----F-S-RKRM- -------------------- -------------------- -------------------- -------------------- -------------------- ------------KGAD---- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ---A--GLRTL--------- ------------A------- R------------E--L-L- G-T--ED-LQ--V------L --A-I--W-LTGDK-ETA-- I-----L------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ----G--------------- ------F---------V-CC R--P-QK---V--------- ----AIGDG-NDV-MIQ-A- -G-GI-G-EG-QA----D-- ---F--L--LL-VHG---Y- R------------------- -------------------- -------T--P--------- ----------P-LY------ --------F----------- -------------------- -------------------- ------------W------- ---------S---------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -----
Identical in 31 out of 35 sequences                         -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ------------------Y- -------------------- -------------------- -------------------- ------------N------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ----------G--------- ----D--------------- -T---DGE---K-------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ---K---------------- -------------------- -------------------- -------------------- -------------P-S---- --------------D----- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------LG-------DKTG TLT-N-M------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ---Y---SPDE-A------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ------L----F----KRM- -------------------- -------------------- -------------------- -------------------- -------------------- ------------KGAD---- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ------GLRTL--------- ------------A------- R------------E------ --T--ED-LQ--V------L --A----W-LTGDK-ETA-- ------L------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ----------------V--C R--P-QK------------- -----IGDG-NDV-MI--A- -G-G--G-EG-QA----D-- ---F-----L---HG---Y- R------------------- -------------------- ----------P--------- ----------P-LY------ -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -----
Identical in 34 out of 35 sequences                         -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------P------ --------------D----- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- --------G-------DKTG -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------S-DE-A------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -----------F-------- -------------------- -------------------- -------------------- -------------------- -------------------- ------------KGA----- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- --------R-L--------- -------------------- -------------E------ --T---D-LQ---------- ---------LTGD---TA-- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- R--P--K------------- --------G-ND--M----- -G-G----EG--A----D-- ---F---------HG----- -------------------- -------------------- -------------------- ----------P--------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -----  
Conserved segments in all P-type ATPases                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     aaaaaaaaaaaaaaaaa aaaaaaaa           b bbbbbbbbbbbbbbbbbbb                                                                                                                                                                                                                                                                                                           ccccccccccccccccc ccccccccc                                                                                                 ddddddddddddddddddd ddddd                                                                                                                                        eeeee eeeeeeeeeeeeeeeeeeee eeeeeeeeeee                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   fffffffff ffffffffffffffffffff ffffffffffffffffffff ffffffff                                                                                                                                                                                 ggg gggggggggggggggg  gg gggggggggggggggggggg ggggg  hhhh hhhhhhhh hhhhhhhhhhhhhhhhhhh                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                               
Transmembrane helices                                                                                                                                                                                                                                                                                                        111111111111111 11111111     2222222 22222222222222222                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                     33333 33333333333333333                                               444444444444444444                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                55555555555555555 555              666 66666666666666666                                 777777777777 7777777777                 88888888888888 888888888             9999999999999999999 99                       0000000000000000 000000000
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Last update 16-6-2003 by Kristian B. Axelsen.