P-type ATPases in a number of organisms

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Saccharomyces cerevisiae
P38995 1B Cu+ CCC2 / ydr270w 48
P38360 1B
PCA1 / ybr295w 52
P13586 2A Ca2+ PMR1 / ygl167c 133
P38929 2B Ca2+ PMC1 / ygl006w 129
P13587 2D Na+ ENA1 / ydr040c 94
Q01896 2D
ENA2 / ydr039c (94)
Q12691 2D
ENA5 / ydr038c (94)
P05030 3A H+ PMA1 / ygl008c 86
P19657 3A H+ PMA2 / ypl036w 87
P39524 4
DRS2 / yal026c 15
P40527 4
NEO1 / yil048w 9
P32660 4
DNF1 / yer166w 18
Q12675 4
DNF2 / ydr093w 17
Q12674 4
DNF3 / ymr162c 13
P39986 5
SPF1 / yel031w 6
Q12697 5
yor291w 1

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Caenorhabditis elegans
O17737 1B
cua-1 / Y76A2A.2 -
Q9XTG4 2A
pmr-1 / ZK256.1a -
Q9XTG6 2A
sca-1 / K11D9.2a -
O45215 2B
mca-1 / W09C2.3 127
O76833 2B
mca-2 / R05C11.3 -
O76832 2B
mca-3 / Y67D8A.10a -
Q27461 2C Na+ / K+ eat-6 / B0365.3 101
O16331 2C
C09H5.2 -
O16436 2C
C02E7.1 -
O45240 2C
C01G12.8 98
Q8WQB1 NB! 2C
Y105E8A.12 -
Q10463 4
T24H7.5b 11
O45878 4
F36H2.1 8
P91203 4
F02C9.3 -
O18182 NB! 4
W09D10.2 -
Q9U280 4
Y49E10.11 / Y111B2 -
Q9TXV2 4
H06H21.10 / Y17G9A -
Q21286 5
K07E3.7 3
Q27533 5
W08D2.5 2
P90747 5
C10C6.6 / Y42E10 5
Q9N323 5
Y59H11AR.2 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Drosophila melanogaster
Q9VYT4 1B
CG1886 -
P22700 2A
DRSERCA / CA-60A / CG3725 146
Q9VNR2 2A
CG7651 -
Q9V4C7 2B
CG2165 -
P13607 2C Na+/K+ NA-P / CG5670 102
Q9W5Y2 2C
Jyalpha / CG17923 -
Q9W248 2C
CG3701 -
Q8T0I4 4
CG17034 -
Q9VGD4 4
CG14741 -
Q9VLB5 4
CG18419 -
Q9VXG7 4
CG9981 -
Q9VXG6 4
CG4301 -
Q9VK04 4
CG6263 -
Q9Y139 5
CG6320 / BcDNA:GH06032 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Arabidopsis thaliana
Q9M3H5 1B
HMA1 / At4g37270 -
Q9SZW4 1B
HMA2 / At4g30110 -
Q9SZW5 h 1B
HMA3 / At4g30120 -
O64474 1B
HMA4 / At2g19110 -
Q9S7J8 1B
RAN1 / At5g44790 -
Q9SZC9 1B
PAA1 / At4g33520 -
Q9SH30 1B
HMA5 / At1g63440 -
Q9C594 1B
At5g21930 -
P92939 2A Ca2+ ECA1 / ACA3 / At1g07810 152
O23087 2A
ECA2 / ACA5 / At4g00900 -
Q9SY55 2A
ECA3 / ACA6 / At1g10130 -
Q9XES1 2A
ECA4 / At1g07670 (152)
Q37145 2B
ACA1 / PEA1 / At1g27770 120
O81108 2B Ca2+ ACA2 / At4g37640 -
O22218 2B Ca2+ ACA4 / At2g41560 -
O64806 2B
ACA7 / At2g22950 - c
Q9LF79 2B
ACA8 / At5g57110 -
Q9LU41 2B
ACA9 / At3g21180 -
Q9SZR1 2B
ACA10 / At4g29900 -
Q9M2L4 2B
ACA11 / At3g57330 (119)
Q9LY77 2B
ACA12 / At3g63380 -
Q9LIK7 2B
ACA13 / At3g22910 -
P20649 3A H+ AHA1 / At2g18960 (68)
P19456 3A H+ AHA2 / At4g30190 68
P20431 3A H+ AHA3 / At5g57350 69
Q9SU58 3A
AHA4 / At3g47950 (78)
Q9SJB3 3A
AHA5 / At2g24520 -
Q9SH76 3A
AHA6 / At2g07560 -
Q9LY32 3A
AHA7 / At3g60330 -
Q9M2A0 3A
AHA8 / At3g42640 -
Q42556 3A
AHA9 / At1g80660 74
Q43128 3A
AHA10 / At1g17260 80
Q9LV11 3A
AHA11 / At5g62670 -
Q9T0E0 j 3A
At4g11730 -
P98204 4
ALA1 / At5g04930 -
P98205 4
ALA2 / At5g44240 -
Q9XIE6 4
ALA3 / At1g59820 -
Q9LNQ4 4
ALA4 / At1g17500 -
Q9SGG3 4
ALA5 / At1g72700 -
Q9SLK6 4
ALA6 / At1g54280 -
Q9LVK9 4
ALA7 / At3g13900 -
Q9LK90 4
ALA8 / At3g27870 -
Q9SX33 4
ALA9 / At1g68710 -
Q9LI83 4
ALA10 / At3g25610 -
Q9SAF5 4
ALA11 / At1g13210 -
P57792 4
ALA12 / At1g26130 -
Q9LT02 5
At5g23630 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Homo sapiens
Q04656 1B Cu+ ATP7A / MNK 49
P35670 1B Cu+ ATP7B / WND 51
O14983 2A Ca2+ ATP2A1 / SERCA1 -
P16615 2A Ca2+ ATP2A2 / SERCA2 141
Q93084 2A Ca2+ ATP2A3 / SERCA3 (145)
P98194 2A
ATP2C1 (132)
O75185 2A
ATP2C2 -
P20020 2B Ca2+ ATP2B1 / PMCA1 124
Q01814 2B Ca2+ ATP2B2 / PMCA2 126
Q16720 2B Ca2+ ATP2B3 / PMCA3 125
P23634 2B Ca2+ ATP2B4 / PMCA4 123
P05023 2C Na+ / K+ ATP1A1 / NaKalpha1 104
P50993 2C Na+ / K+ ATP1A2 / NaKalpha2 109
P13637 2C Na+ / K+ ATP1A3 / NaKalpha3 106
Q13733 2C Na+ / K+ ATP1A4 / NaKalpha4 (110)
P54707 2C H+ / K+ ATP12A 115
P20648 2C H+ / K+ ATP4A 112
Q9Y2Q0 4
ATP8A1 / ATPase II (14)
Q9NTI2 4
ATP8A2 -
O43520 4
ATP8B1 / FIC1 -
P98198 4
ATP8B2 -
O60423 4
ATP8B3 -
Q8TF62 4
AT8B4 -
O75110 4
ATP9A -
O43861 4
ATP9B -
O60312 4
ATP10A -
O94823 4
ATP10B -
Q9P241 4
ATP10D -
P98196 4
ATP11A -
Q9Y2G3 4
ATP11B -
Q8NB49 4
ATP11C -
Q9HD20 5
ATP13A1 -
Q9NQ11 5
ATP13A2 -
Q9H7F0 5
ATP13A3 -
Q8N1Q9 e 5
ATP13A4 -
Q4VNC0 e 5
ATP13A5 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Schizosaccharomyces pombe
O59666 1B
SPBC29A3.01 -
O59868 2A
PGAK.2 / SPBC31E1.02C -
Q9HDW7 2B
SPAPB2B4.04c -
P22189 2D Ca2+ CTA3 / SPBC24E9.06 93
P09627 3A H+ PMA1 / SPAC1071.10c 90
P28876 3A H+ PMA2 / SPCC1020.01c / SPCC1393.01 89
Q10309 4
SPAC6C3.05C 10
Q09891 4
SPAC24B11.12C 16
O36028 4
SPAC4F10.16c -
O94296 4
SPBC887.12 -
Q9UT43 4
SPAC821.13c -
O14022 5
SPAC29A4.19c -
O14072 5
SPAC2E11.07c -
O74431 5
SPCC1672.11c -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Aquifex aeolicus
O67432 1B
CtrA2 -
O67203 1B
CtrA3 -
O66938 2
CtrA1 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Bacillus halodurans
Q9KEV5 1B
BH0744 -
Q9K5Q2 1B
BH4036 -
Q9KFC7 1B
BH0557 -
Q9K9X9 2A
PacL / BH2515 -
Bacillus subtilis
O31688 1B
YkvW -
O32219 1B
YvgW -
O32220 1B
YvgX -
O34431 2A
YloB -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Campylobacter jejuni
Q0PAK1 1A
KdpB / Cj0677 -
Q9PNE0 1B
Cj1155c -
Q9PND4 1B
Cj1161c -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Chlamydia pneumoniae
Q9Z738 1B
ZntA -
Chlamydia trachomatis
O84732 1B
ZntA -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Deinococcus radiodurans
Q9RZP0 1A
KdpB / DRB0083 -
Q9RZ81 1B
DRA0073 -
Q9RRN5 1B
DR2453 -
AE001988 i 1B
DR1440 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Escherichia coli
Present in sequence from genome of strain K12 / MG1655
P03960 1A K+ KdpB / f682 20
P37617 1B Zn2+/Cd2+ ZntA / o732 31
Q59385 1B
YbaR / f834 35
P39168 3B
MgtA / o898 59
Present in sequence from genome of strain O157:H7
Q8X9F9 1A K+ KdpB (20)
Q8X6Q4 1B Zn2+/Cd2+ ZntA (31)
Q8XD24 1B
CopA (35)
P39168 3B
MgtA (59)

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Haemophilus influenzae
P77868 1B
PM1892 -
Pasteurella multocida
Q9CJU9 1B
HI290 34

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Helicobacter pylori
Present in sequence from genome of strain 26695
Q59465 1B Zn2+/Cd2+/Co2+ CadA / HP0791 29
P55989 1B
CopA / HP1072 (33)
O26033 1B
HP1503 -
Present in sequence from genome of strain J99
Q9ZL53 1B
HmcT (29)
Q9ZM69 1B
CopA (33)
Q9ZJB7 1B
FixI -
Additional P-type ATPases from H. pylori not present in the sequenced strains
P77871 1B Cu+ Strain NCTC 11639/UA802
CopA		 33
O08462 1B
Strain NCTC 11638
CopA		 (33)
Q59467 1B
Strain A68
CopA2		 (33)

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Lactococcus lactis
P94888 1B
Plasmid pND302
CadA		 23
Q9FB71 1B
Plasmid pAH82
CadA		 -
Q9CHZ3 Other
YfgQ -
Q9CHA4 1B
CopA -
Q9CH87 1B
CopB -
Q9CFU9 2
YoaB -
Q9CHP9 2A
PacL -
Q9CDH2 2A
YxdC -
Q9CG53 3B
MgtA -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Mycobacterium leprae
P46840 1B
CtpB 40
P46839 1B
CtpA 43
O53114 2
MLCB1913.02 -
Mycobacterium tuberculosis
P96370 1A
KdpB / Rv1030 21
Q10866 1B
CtpG / Rv1992C 30
P96875 1B
CtpC / MtaA g / Rv3270 32
P77894 1B
CtpV / Rv0969 39
Q10876 1B
CtpA / Rv0092 41
Q10877 1B
CtpB / Rv0103c 42
O53160 1B
CtpD / Rv1469 -
O69710 1B
Rv3743c -
Q10860 2A
CtpF / Rv1997 130
Q10900 Other
CtpI / Rv0107c 158
P96271 Other
CtpH / Rv0425c 159
O08365 Other
CtpE / Rv0908 19

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Mycoplasma genitalium
P47317 2
PacL / MG071 157
Mycoplasma pneumoniae
P78036 2
MgtA / G07_872V 156

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Neisseria meningitidis
Serotype A strain Z2491
Q9JU88 1B
NMA1444 -
Q9JU22 1B
NMA1539 -
Serotype B strain MD58
Q9JZI0 1B
NMB1042 -
Q9JZ27 1B
NMB1325 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Pseudomonas aeruginosa
P57698 1A
kdpB / PA1634 -
Q9I3G8 1B
PA1549 -
Q9I147 1B
PA2435 -
Q9HXV0 1B
PA3690 -
Q9HX93 1B
PA3920 -
Q9I3R5 2A
PA1429 -
Q9HUY5 3B
MgtA / PA4895 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Synechocystis PCC6803
P73867 1A
KdpB / slr1729 22
Q59997 1B Co2+ CoaT / CadA / slr0797 28
Q59998 1B Zn2+ ZiaA / slr0798 27
P73241 1B
sll1920 45
P74512 1B
slr1950 38
P37367 2A
Pma1 / sll1614 131
Q59999 2A
PacL / sll0672 153
P74062 2A
PacL / slr0822 155
P73273 2
PacL / sll1076 96

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Thermotoga maritima
Q9WYF3 1B
TM0317 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Treponema pallidum
O83999 1B
TP1036 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Ureaplasma urealyticum
Q9PQU0 1B
TP1036 -
Q9PQM7 2A
PacL -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Vibrio cholerae
Q9KT72 1B
VC1033 -
Q9KPZ7 1B
VC2215 -
Q9KS24 1B
VC1437 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Aeropyrum pernix
Q9YBZ6 1B
APE1454 -
Q9Y8R2 1B
APE2571 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Archaeoglobus fulgidus
O30085 1B
AF0152 -
O29777 1B
AF0473 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Halobacterium sp. (strain NCR-1)
P57699 1A
KdpB -
Q9HSN5 1B
ZntA -
Q9HN90 1B
Cpx / VNG2201G -
Q9HRH2 1B
yvgX / VNG0700G -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Methanobacterium thermoautotrophicum f
O26511 1B
MTH411 -
O26849 1B
MTH755 -
O27578 1B
MTH1535 -
O27082 2A
MTH1001 -
O27560 2A
MTH1516 -

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Methanococcus jannaschii
Q58623 3A
MJ1226 61

Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Pyrococcus abyssi
Q9V060 1B
PAB0626 -
Accession number ATPase Type Specificitya Protein name/Locus Number in phylogenetic tree
Thermoplasma acidophilum
P57700 1A
Ta1309 -
Q9HJ30 1B
Ta1143 -
Q9HJC5 3A
Ta1045 -

Footnotes:
a The ion specificity of the P-type ATPases is shown, when it is known. PL: Phospholipids.
b No protein sequence has been provided with the genomic DNA data.
c The protein shows 95% identity with ACA2.
d No protein sequence has been provided with the otherwise finished genomic DNA data.
e This is only a partial P-type ATPase.
f Two fragments of a Type IIA P-type ATPase have been designated the locus names MTH481 and MTH482.
g The DNA sequence of MtaA contains two frameshift errors. If these are corrected, the protein sequence is identical to CtpC.
h Alignment of type IB P-type ATPases have indicated that the suggested protein sequence should be changed at several exon border positions. There is, furthermore, a frameshift mutation in the contig sequenced.
i The gene contains according to the Deinococcus radiodurans web site an authentic frameshift and has, therefore, not been annotated in the EMBL entry.
j The sequence does not constitute a full length protein, as the protein encoded by the genomic clone misses 100 amino acids from the universally conserved regions f and g. The C-termininal 90 amino acids are, furthermore, exchanged for a completely unrelated sequence of 45 amino acids. The protein does, therefore, not constitute a functional H+-ATPase in its current form.
Go to Front page