Alignment of P2B ATPases (Plasma membrane type Ca2+)

The alignment was performed on The Danish Biotechnological Database with the programme CLUSTALW with default settings. The alignment of the N- and C-termini was refined by hand.
The grouping of P-type ATPases and the nomenclature is adopted from the work described in Axelsen, K.B. & Palmgren, M.G. (1998) J. Mol. Evol. 46: 84-101.
The sequence numbers refer to the position of the sequence in a phylogenetic tree of P-type ATPases.
The sequences with sequence numbers in parantheses are not included in the phylogenetic tree, but show more than 90 % sequence identity with the sequence with the specified number.
The positions of the transmembrane helices 1-7 are indirectly determined from the crystal structure of rabbit SerCa1. Due to low similarity in the C-terminal region the transmembrane helices could not be positioned this way and are predicted with the method of von Heijne (the toppred server). The borders of transmembrane helices 1-7 might change by one or two amino acids, the three others might change somewhat more.
The segments a-h conserved in all P-type ATPases are the amino acid stretches used for the phylogenetic analysis.
Amino acids in the alignment shown in CAPITALS are present in 85% (22 of 26) of the P2B ATPases.
Number Accession    Organism                  Name
used   number                                                    1                                                                                                    100 101                                                                                                  200 201                                                                                                  300 301                                                                                                  400 401                                                                                                  500 501                                                                                                  600 601                                                                                                  700 701                                                                                                  800 801                                                                                                  900 901                                                                                                 1000 1001                                                                                                1100 1101                                                                                                1200 1201                                                                                                1300 1301                                                                                                1400 1401                                                                                                1500 1501                                                                                                1600 1601                                                                                                1700 1701                     1728
  118  Q27829    Paramecium tetraurelia                          .................... .................... .................... .................... .................... .mqspnksalshrdqaddvr plavqeqldlgpFkitpqqL qqifhlntrrstceeldylv qqGgignpissfinldwlid gLhtsikdGind..dqd... .qRiqvyGhNkrivrppqty cellWnAleDfTmrvLlias iaSivievat.......... .................... .adnehrhlawieGfaIfva vlvctnVaAmnDyskekQFr kLnaasekskivaViRnkql iqiheeqvlVGDicklieGm eiPADGvlldasdvkvDESS mTGEthsitkgtinqclkqk welqdegvqfgeq....... ..drfkipsPaLlSGTrVle Ge.glflicvVGdlsclGqs ifrirgrrrcnn........ .................... .................... ..............nlinll etpLQvkLtmiAedIGkfGl isavliffvLmirfaiergi an.................. ...............ewdhs khwmeilnf....iilsivv ltVAiPEGLPLsVTisLAys vqKMMdDknLVRkmyACETM GgAdsICSDKTGTLTmNkMv ltkiwnkqfyeidylak... .......eqnlsqlvsksme nlflealccNssaeltpe.. .................... .................... .............sGskTEi aiLeylqk..ari...dyrr mReqvn.......fikknpF sSarKrMsvivdtkhng..l pvkRlyiKGASEIivqslth mhtyddqklklgvkdiq.ei eriIsqmAkqsLRiicvAyl dlrgded............l qkmngkvydietqdltflgl fGImDnlRegVkdavtkCkq AGIkVRMVTGDNseTArAIA mnCGIieq..gdgqaiviEG aeFmkevggvvckncttelc kcakssneaekngtslrvdt lgntsrfrqiyPqiaVmARS rPtDKyamiiglk.....ec ehiVAVTGDGTNDaPALkkA DvGfAMGkaGTqVAKdasai IlmeDNFsdIVkavmWGRni fqsIrKFlQFQLTVNVvAvg ftlissallkqd........ ................vLkp iQmLWVNlIMDsfasLALAT EpPs.eiLlkdrPysRsesi vtnkMikhIigqaiYQlavi lvLvflaqefipeyaddydd virdriqekieedsdfvfeq sslyhpkyntdyypeslkir sgrfltvtsendfedifnef rvpsrhyTfiFNaFVfmQvF NfiNssklnd.......... ....eiNvFanmcnkqyilf ylslmFvlivffiiilQiil vtFgslafScysyyg..... .ltiqqWvisliiGlvglvv sfilklIPeqhviesyfvqi cpktqnaesktldkkpsgil elrrgsslrkk......... .................... .................... .................... .................... .................... .................... .................... .................... ........
  119  P93067    Brassica oleracea         BCA1                  .................... .................msn llkdf.qveaknpslearqr wrssvstiknrarrfrmisn leklaenekkrcqiqekirv afyvqkaalqfidagtrr.. eykltdevrqagFhveadeL asmvrnhd.......trslt ksGgaeg..........iaq kLsvslteGvrsnd.....l diRekiyGaNryaekparsF ltfvWeAlqDvTLiILmvcA vvSigvgvat.......... .................... ....egfpkGmydGtgIlls iilVvmVTAisDyrqslQFr dLdrekkk.iniqVtRdGnr qevsiddlvVGDvvhlsiGD rvPADGvfIsgynleiDESS lsGESepshvnkek...... .................... .........PfLlSGTkVqn Gs.akMlvTtVGmrtewGkl metlseggede......... .................... .................... .................... .tpLQvkLngvAtiIGkiGl gfavltfvvLcvrfvigka. ..aaggi............. ...............sewss edaltlldy....faiaVTi iVVAVPEGLPLAVTlsLAfa mkqlMkDraLVRhLaACETM GssTcICtDKTGTLTtNhMv Vnkvwicenikerre..... ........enfelnlseqvk niliqaIfqNtgsevvkdke .................... .................... ........gktqilGspTEr aiLefgll.Lgg....dvem qgreh.......kilkiepF nSdkKkMsvltshsgg.... .kvRafcKGASEIvLrmCek vvdssGksvplseekia.av sevIegfAseaLRtlclvyt dldeapsgd........... .........lpdggytlvav vGIkDPvRPgVrkavqtCqn AGItVRMVTGDNisTAkAIA keCGIlt.....aggvaiEG seFrnlpphEm......... .................... .......railPkiqVmARS lPlDKhtLVnnlr.....ki geVVAVTGDGTNDaPALhes DiGlAMGIaGTeVAKEnaDv IimDDNFatIVnvarWGRaV YinIqKFvQFQLTVNVvAli inFvsacitgsa........ ................PLtA VhlLWVNmIMDTlgaLALAT EpPn.egLmkRqPiGRtasf ItraMwrNIigqsiYQlivl giLnfyGk.qildlngp... .................... .................... .................... dstavlnTiiFNsFVfcQvF NEvNsReie........... ....kiNvFaGmfs...... ..swvFvavmtaTtgfQliI vellGafaStvpLs...... ...wqhWllciviGsismil avglkcIPvesnshhdgyel lpsgps..dsa......... .................... .................... .................... .................... .................... .................... .................... .................... .................... ........
   -   O22218    Arabidopsis thaliana      ACA4 / T32G6.8        .................... .................msn llrdf.eveaknpslearqr wrssvsivknrtrrfrnird ldkladyenkkhqiqekirv affvqkaalhfidaaarp.. eykltdevkkagFsieadeL asmvrknd.......tksla qkGgvee..........lak kvsvslseGirsse.....v piRekifGeNrytekparsF lmfvWeAlhDiTLiILmvcA vvSigvgvat.......... .................... ....egfprGmydGtgIlls illVvmVTAisDykqslQFr dLdrekkk.iivqVtRdGsr qeisihdlvVGDvvhlsiGD qvPADGifIsgynleiDESS lsGESepshvnkek...... .................... .........PfLlSGTkVqn Gs.akMlvTtVGmrtewGkl metlvdggede......... .................... .................... .................... .tpLQvkLngvAtiIGkiGl sfavltfvvLcirfvldka. ..tsgsf............. ...............tnwss edaltlldy....faisVTi iVVAVPEGLPLAVTlsLAfa mkKlMsDraLVRhLaACETM GssTcICtDKTGTLTtNhMv Vnkvwicdkvqerqeg.... ......skesfelelseevq stllqgIfqNtgsevvkdkd .................... .................... ........gntqilGspTEr aiLefgll.Lgg....dfnt qRkeh.......kilkiepF nSdkKkMsvlialpgg.... .gaRafcKGASEIvLkmCen vvdsnGesvplteerit.si sdiIegfAseaLRtlclvyk dldeapsge........... .........lpdggytmvav vGIkDPvRPgVreavqtCqa AGItVRMVTGDNisTAkAIA keCGIyt.....egglaiEG seFrdlsphEm......... .................... .......raiiPkiqVmARS lPlDKhtLVsnlr.....ki geVVAVTGDGTNDaPALheA DiGlAMGIaGTeVAKEnaDv IimDDNFktIVnvarWGRaV YinIqKFvQFQLTVNVvAli inFvsacitgsa........ ................PLtA VQlLWVNmIMDTlgaLALAT EpPn.egLmkRaPiaRtasf ItktMwrNIagqsvYQlivl giLnfaGk.sllkldgp... .................... .................... .................... dstavlnTviFNsFVfcQvF NEiNsReie........... ....kiNvFkGmfn...... ..swvFtwvmtvTvvfQviI veFlGafaStvpLs...... ...wqhWllsiliGslnmiv avilkcvPvesrhhhdgydl lpsgpsssnsa......... .................... .................... .................... .................... .................... .................... .................... .................... .................... ........
  120  Q37145    Arabidopsis thaliana      ACA1 / PEA1           .................... ................mesy lnenfgdvkpknssdealqr wrklcwivknpkrrfrftan lskrseaeairrsnqekfrv avlvsqaalqfinslklss. eytlseevrkagFeicpdeL gsiveghd.......lkklk ihGgteg..........lte kLstsiasGist.sedl..l svRkeiyGiNqftespsrgF wlfvWeAlqDtTLmILaacA fvSlivgilm.......... .................... ....egwpiGahdGlgIvas illVvfVTAtsDyrqslQFk dLdaekkk.ivvqVtRdklr qkisiydllpGDvvhlgiGD qiPADGlfIsgfsvlinESS lTGESepvsvsveh...... .................... .........PfLlSGTkVqd Gs.ckMlvTtVGmrtqwGkl matlseggdde......... .................... .................... .................... .tpLQvkLngvAtiIGkiGl ffavitfavLvqglanqkr. ..ldnsh............. ...............wiwta delmamley....favaVTi vVVAVPEGLPLAVTlsLAfa mkKMMnDkaLVRnLaACETM GsATtICSDKTGTLTtNhMt VVkaciceqakevngpd... ......aamkfasgipesav klllqsIftNtggeivvgkg .................... .................... ........nkteilGtpTEt alLefgls.Lgg....dfqe vRqas.......nvvkvepF nStkKrMgvvielper.... .hfRahcKGASEIvLdsCdk yinkdGevvpldeksts.hl kniIeefAseaLRtlclAyf eigdefslea.......... ........pipsggytcigi vGIkDPvRPgVkesvaiCks AGItVRMVTGDNltTAkAIA reCGIlt.....ddgiaiEG peFreksdeEl......... .................... .......lkliPklqVmARS sPmDKhtLVrllrt....mf qeVVAVTGDGTNDaPALheA DiGlAMGIsGTeVAKEsaDv IilDDNFstIVivakWGRsV YinIqKFvQFQLTVNVvAli vnFlsacltgna........ ................PLtA VQlLWVNmIMDTlgaLALAT EpPq.ddLmkRsPvGRkgnf IsnvMwrNIlgqslYQlvii wcLqtkGk.tmfgldgp... .................... .................... .................... dsdltlnTliFNiFVfcQvF NEissReme........... ....kidvFkGilk...... ..NyvFvavltcTvvfQviI iellGtfadttpLn...... ...lgqWlvsiilGflgmpv aaalkmIPvgsh........ .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ........
   -   O81108    Arabidopsis thaliana      ACA2 / F19F18.130     .................... ................mesy lnenf.dvkakhsseevlek wrnlcgvvknpkrrfrftan lskryeaaamrrtnqeklri avlvskaafqfisgvsps.. dytvpedvkaagFeicadeL gsiveshd.......vkklk fhGgvdg..........lag kLkasptdGlst.eaaq..l sqRqelfGiNkfaesemrgF wvfvWeAlqDmTLmILgvcA fvSlivgiat.......... .................... ....egwpkGshdGlgIaas illVvfVTAtsDyrqslQFr dLdkekkk.itvqVtRnGfr qklsiydllpGDivhlaiGD qvPADGlflsgfsvviDESS lTGESepvmvnaqn...... .................... .........PfLmSGTkVqd Gs.ckMmiTtVGmrtqwGkl matlteggdde......... .................... .................... .................... .tpLQvkLngvAtiIGkiGl ffavvtfavLvqgmfmrkl. ..stgth............. ...............wvwsg dealelley....faiaVTi vVVAVPEGLPLAVTlsLAfa mkKMMnDkaLVRhLaACETM GsATtICSDKTGTLTtNhMt VVkscicmnvqdvank.... .......gsslqseipesav klliqsIfnNtggevvvnkh .................... .................... ........gktellGtpTEt aiLelgls.Lgg....kfqe eRksy.......kvikvepF nStkKrMgvvielpegg... .rmRahtKGASEIvLaaCdk vvnssGevvpldeesik.yl nvtInefAneaLRtlclAym dieggfspdd.......... ........aipasgftcvgi vGIkDPvRPgVkesvelCrr AGItVRMVTGDNinTAkAIA reCGIlt.....ddgiaiEG pvFreknqeEl......... .................... .......leliPkiqVmARS sPmDKhtLVkqlrt....tf deVVAVTGDGTNDaPALheA DiGlAMGIaGTeVAKEsaDv IilDDNFstIVtvakWGRsV YinIqKFvQFQLTVNVvAlv vnFssacltgsa........ ................PLtA VQlLWVNmIMDTlgaLALAT EpPn.deLmkRlPvGRrgnf ItnaMwrNIlgqavYQfivi wiLqakGk.amfgldgp... .................... .................... .................... dstlmlnTliFNcFVfcQvF NEissReme........... ....eidvFkGild...... ..NyvFvvvigaTvffQiiI ieFlGtfaSttpLt...... ...itqWifsifiGflgmpi aaglktIPv........... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ........
   -   O64806    Arabidopsis thaliana      T20K9.16 / F21P24.1   .................... ................mesy lnsnf.dvkakhsseevlek wrnlcsvvknpkrrfrftan lskryeaaamrrtnqeklri avlvskaafqfisgvsps.. dykvpeevkaagFdicadeL gsiveghd.......vkklk fhGgvdg..........lsg kLkacpnaGlstgepeq..l skRqelfGiNkfaeselrsF wvfvWeAlqDmTLmILgvcA fvSlivgiat.......... .................... ....egwpqGshdGlgIvas illVvfVTAtsDyrqslQFr dLdkekkk.itvqVtRnGfr qkmsiydllpGDvvhlaiGD qvPADGlflsgfsvviDESS lTGESepvmvtaqn...... .................... .........PfLlSGTkVqd Gs.ckMlvTtVGmrtqwGkl matlseggdde......... .................... .................... .................... .tpLQvkLngvAtiIGkiGl sfaivtfavLvqgmfmrkl. ..slgph............. ...............wwwsg ddalelley....faiaVTi vVVAVPEGLPLAVTlsLAfa mkKMMnDkaLVRhLaACETM GsATtICSDKTGTLTtNhMt VVkscicmnvqdvask.... .......ssslqsdipeaal klllqlIfnNtggevvvner .................... .................... ........gkteilGtpTEt aiLelgls.Lgg....kfqe eRqsn.......kvikvepF nStkKrMgvvielpegg... .riRahtKGASEIvLaaCdk vinssGevvplddesik.fl nvtIdefAneaLRtlclAym diesgfsade.......... ........gipekgftcigi vGIkDPvRPgVresvelCrr AGImVRMVTGDNinTAkAIA reCGIlt.....ddgiaiEG pvFreknqeEm......... .................... .......leliPkiqVmARS sPmDKhtLVkqlrt....tf deVVAVTGDGTNDaPALheA DiGlAMGIaGTeVAKEiaDv IilDDNFstIVtvakWGRsV YinIqKFvQFQLTVNVvAli vnFssacltgsa........ ................PLtA VQlLWVNmIMDTlgaLALAT EpPn.neLmkRmPvGRrgnf ItnaMwrNIlgqavYQfiii wiLqakGk.smfglvgs... .................... .................... .................... dstlvlnTliFNcFVfcQvF NEvssReme........... ....eidvFkGild...... ..NyvFvvvigaTvffQiiI ieFlGtfaSttpLt...... ...ivqWffsifvGflgmpi aaglkkIPv........... .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ........
   -   Q9LF79    Arabidopsis thaliana      ACA8 / MUL3.5         .............mtsllks spgrrrggdvesgksehads dsdtfyi.psknasierlqq wrkaalvl.nasrrfrytld lkkeqetremr....qkirs hahallaanrfmdmgresgv ekttgpatpagdFgitpeqL vimskdhn.......sgale qyGgtqg..........lan lLktnpekGisg.dddd..l lkRktiyGsNtyprkkgkgF lrflWdAchDlTLiILmvaA vaSlalgikt.......... .................... ....egikeGwydGgsIafa vilVivVTAvsDykqslQFq nLndekrn.ihleVlRgGrr veisiydivVGDviplniGn qvPADGvlIsghslalDESS mTGESkivnkdank...... .................... ........dPfLmSGckVad Gn.gsMlvTgVGvntewGll masisedngee......... .................... .................... .................... .tpLQvrLngvAtfIGsiGl avaaavlviLltryftghtk dnnggpq............. ...............fvkgk tkvghviddvvkvltvaVTi vVVAVPEGLPLAVTltLAys mrKMMaDkaLVRrLsACETM GsATtICSDKTGTLTlNqMt VVesyaggkktdteqlp... ................atit slvvegIsqNttgsifvpeg g................... .................... ........gdleysGspTEk aiLgwgvk.Lgm....nfet aRsqs.......silhafpF nSekKrggvavktadg.... .evhvhwKGASEIvLasCrs yidedGnvapmtddkas.ff kngIndmAgrtLRcvalAfr tyeaekvptg.......... ..eelskwvlpeddlillai vGIkDPcRPgVkdsvvlCqn AGvkVRMVTGDNvqTArAIA leCGIlssdadlseptliEG ksFremtdaEr......... .................... .......dkisdkisVmgRS sPnDKllLVqslr.....rq ghVVAVTGDGTNDaPALheA DiGlAMGIaGTeVAKEssDi IilDDNFasvVkvvrWGRsV YanIqKFiQFQLTVNVaAlv invvaaissgdv........ ................PLtA VQlLWVNlIMDTlgaLALAT EpPt.dhLmgRpPvGRkepl ItniMwrNlliqaiYQvsvl ltLnfrGi.silglehevh. .................... .................... ...................e hatrvknTiiFNaFVlcQaF NEfNaRkpd........... ....ekNiFkGvik...... ..NrlFmgiiviTlvlQviI veFlGkfaSttkLn...... ...wkqWlicvgiGviswpl alvgkfIPvpaapisnklk. .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ........
   -   Q9LU41    Arabidopsis thaliana      ACA9 / MXL8.3         mstsssngllltsmsgrhdd meagsakteehsdheelqhd pddpfdidntknasveslrr wrqaalvl.nasrrfrytld lnkeehydnrrr....mira haqviraallfklageqqig fgsstpaastgnFdidlekL vsmtrnqn.......msnlq qyGgvkg..........vae kLksnmeqGine.deke..v idRknafGsNtypkkkgknF fmflWeAwqDlTLiILiiaA vtSlalgikt.......... .................... ....eglkeGwldGgsIafa vllVivVTAvsDyrqslQFq nLndekrn.iqleVmRgGrt vkisiydvvVGDviplriGD qvPADGvlIsghslaiDESS mTGESkivhkdqks...... .................... .........PfLmSGckVad Gv.gnMlvTgVGintewGll masisedtgee......... .................... .................... .................... .tpLQvrLnglAtfIGivGl svalvvlvaLlvryftgttq dtngatq............. ...............fikgt tsisdivddcvkiftiaVTi vVVAVPEGLPLAVTltLAys mrKMMaDkaLVRrLsACETM GsATtICSDKTGTLTlNqMt VVetyaggskmdvadnp... ............sglhpklv alisegvaqNttgnifhpkd g................... .................... ........geveisGspTEk aiLswayk.Lgm....kfdt iRses.......aiihafpF nSekKrggvavlrgds.... .evfihwKGAaEIvLacCtq ymdsnG.tlqsiesqke.ff rvaIdsmAknsLRcvaiAcr tqelnqvpkeq......... ..edldkwalpedelillai vGIkDPcRPgVreavriCts AGvkVRMVTGDNlqTAkAIA leCGIlssdteaveptiiEG kvFrelsekEr......... .................... .......eqvakkitVmgRS sPnDKllLVqalr.....kn gdVVAVTGDGTNDaPALheA DiGlsMGIsGTeVAKEssDi IilDDNFasvVkvvrWGRsV YanIqKFiQFQLTVNVaAli invvaamssgdv........ ................PLkA VQlLWVNlIMDTlgaLALAT EpPt.dhLmhRtPvGRrepl ItniMwrNllvqsfYQvavl lvLnfaGl.silglnhenh. .................... .................... ...................a havevknTmiFNaFVmcQiF NEfNaRkpd........... ....emNvFrGvnk...... ..NplFvaivgvTfilQiiI vtFlGkfahtvrLg...... ...wqlWlasiiiGlvswpl aivgklIPvpktpmsvyfkk .................... .................... .................... .................... .................... .................... .................... .................... .................... .................... ........
  121  Q27642    Entamoeba histolytica                           .................... .................... .................... .................... .................... ............mggkpskq eeqkkeytgqpegtpyydiq gcelakmvst...nnkeiyd kyGgvig..........isk ilevdldkGicd.es....y skRqeqfGkNrtpdavivpF wkiwfeAlqDkTLiILiiaA ivSlilafavpnsvdkclak ...................e needkelntdwieGvaIlia vlaVslggsasDyskqkkFl aLsqeekd.vgikViRnGen qktsifnlsVGDivnldvGD iiPADGiyIhgndlrvDqaS mTGESvavrktsen...... .................... .........fsmmSGTkVmd Gn.gkMlvvaVGpnslwGkt meavnqnksap......... .................... .................... .................... .tpLQenLdelAvkIGylGm gcgalvfivLtiyyivsqft hkdvlkadeekgiiagclec nvtredvmwneycekysfdw ssltglidy....fiigVTi iVVAVPEGLPLAVTisLAys mkqMfkDnnLVRhLkvCETM sncTnICSDKTGTLTeNrMt VVngwfggikmetrd..... ..........qkfqflknmk klinmnIsiNsspsttlise n................... .................... ........gqinviGnkTEg alLmyvke.rgv....dyle iRkrne.....nniyqmfaF sSakKrMntlvwidkpn... .tiRmftKGApEmiLekCqy ymngqGeikeiteevrq.el eecqvewAskgyRtlslsyk ditpanrnn........... ..leekyevaneegsiiisl fGIeDPvRreVpgavatCqr AGIiVRMVrGDNiaTArsIA kqCnIis....rendiaiEG pkFaeltdeEi......... .................... .......ieklenlrViARc sPqDKerLVkllis.....q geVVAVTGDGTNDvPALkaA DvGlAMGIrGTdVAKqasDi vilDDNFqsIVnsvngeRcV YdnIrKFlQFQLTVNisAla lcvigsifiges........ ................PLnA lQmLWVNlIMDTmaaLALgT Ektn.rfiidRkPfGRfdsl IsniMirNIivqtvYQlelc yqLflqkyipflnspcgfvk tvghsggedfsk........ .................... ....ycagdnigfksindvk ndtielqTlvFNiFVfcQvF NEfNsRkvng.......... ....ehNvFsnlft...... ..NfiFltiigvTiiiQtiI vqFlGilfdgvpfipsqgqy glswqgWvlslllscmtlvi gqisffIPvptskpkkfknq pslltkilccgfcnkkdvks sssessddddnlekksllsn .................... .................... .................... .................... .................... .................... .................... .................... ........
  122  Q64542    Rattus norvegicus         ATP2B4 / PMCA4        .................... .................... .................... .................... .................... ...........mtnpsghnl pansvaesyegeFgctlmdL rklmelraad...avtqisa hyGsvqe..........ica rLktspveGlsg.npad..l ekRrlvfGkNmippkkpktF lelvWeAlqDvTLiILeiaA iiSlvlsfyrppggenei.. .............cghivsn peedeegetGwieGaaIlas viiVvfVTAfnDwskekQFr gLqsrieleqkfsiiRnGql iqlpvaeivVGDiaqvkyGD llPADGilIqgndlkiDESS lTGESdhvkktldk...... .................... ........dPmLlSGThVme Gs.grMvvTaVGinsqtGii ftllganeeeddekkkkgkk q......gvsenrnkaktqd gvaleiqplnsqegldseek e.........kkaskgpkke ksvLQgkLtrlAvqIGkaGl imsiltvliLilyfvvdnfv iqrrawl............. ...............pectp vyiqyfvkf....fiigVTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTmNrMt VVqayiggthyr........ .......qipkpddlppnvl dlivnsIciNsaytskilpp eke................. .................... .......gglprqvGnkTEc glLgfvtd.Lkq....dyqa vRsempe....eklfkvytF nSvrKsMstvirkpegg... ..fRvfsKGASEImLrkCdr ilnkeGgivpfktkdrdnmv rnvIepmAsegLRtigiAyr dfdge............... .epsweneneiftglvciav vGIeDPvRPeVpdainkCkr AGItVRMVTGDNvnTArAIA tkCGIlt...pgddflclEG keFnrlirnEkg........ .................... eveqekldkvwPrlrVlARS sPtDKhtLVkgiidsnigeq rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFsgacitqds........ ................PLkA VQmLWVNlIMDTfasLALAT EpPt.dsLlrRrPyGRnkpl IsrtMmkNIlghavYQlgiv flLvfaGd.klfdidsgrka pl.................. .................... ...................n sppsqhyTivFNtFVlmQlF NEiNsRkihg.......... ....ekNvFaGvyr...... ..NiiFcsvvlgTffcQilI vevgGkpfSctnLt...... ...meqWmwclfiGigellw gqvisaIPtkslkflkeagh gs.......dkeeiskd..a egleeidhaemelrr.gqil wvrglnriqtqievinkgas fkgvlrrqnlsqqldvklvp ssyseavasvrtspstssav tpppvgnqsgqsis...... .................... .................... .................... .................... ........
  123  P23634    Homo sapiens              ATP2B4 / PMCA4        .................... .................... .................... .................... .................... ...........mtnpsdrvl pansmaesregdFgctvmeL rklmelrsrd...altqinv hyGgvqn..........lcs rLktspveGlsg.npad..l ekRrqvfGhNvippkkpktF lelvWeAlqDvTLiILeiaA iiSlvlsfyrpageenel.. .............cgqvatt pedeneaqaGwieGaaIlfs viiVvlVTAfnDwskekQFr gLqcrieqeqkfsiiRnGql iqlpvaeivVGDiaqvkyGD llPADGilIqgndlkiDESS lTGESdhvkksldk...... .................... ........dPmLlSGThVme Gs.grMvvTaVGvnsqtGii ltllgvneddegekkkkgkk q......gvpenrnkaktqd gvaleiqplnsqegidneek d.........kkavkvpkke ksvLQgkLtrlAvqIGkaGl lmsaltvfiLilyfvidnfv inrrpwl............. ...............pectp iyiqyfvkf....fiigiTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTmNrMt VVqayiggihyr........ .......qipspdvflpkvl dlivngIsiNsaytskilpp eke................. .................... .......gglprqvGnkTEc alLgfvtd.Lkq....dyqa vRnevpe....eklykvytF nSvrKsMstvirnpngg... ..fRmysKGASEIiLrkCnr ildrkGeavpfknkdrddmv rtvIepmAcdgLRticiAyr dfddt............... .epswdneneilteltciav vGIeDPvRPeVpdaiakCkq AGItVRMVTGDNinTArAIA tkCGIlt...pgddflclEG keFnrlirnEkg........ .................... eveqekldkiwPklrVlARS sPtDKhtLVkgiidstvgeh rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNlIMDTfasLALAT EpPt.esLlkRrPyGRnkpl IsrtMmkNIlghafYQlivi fiLvfaGe.kffdidsgrka pl.................. .................... ...................h sppsqhyTivFNtFVlmQlF NEiNsRkihg.......... ....ekNvFsGiyr...... ..NiiFcsvvlgTficQifI veFgGkpfSctsLs...... ...lsqWlwclfiGigellw gqfisaIPtrslkflkeagh gt.......tkeeitkd..a egldeidhaemelrr.gqil wfrglnriqtqikvvkafhs slhe.siqkpynqksihsfm thpefaieeelprtplldee eeenpdkaskfgtrvllldg evtpyantnnnavdcn.qvq lpqsdsslqsletsv..... .................... .................... ........
  124  P20020    Homo sapiens              ATP2B1 / PMCA1        .................... .................... .................... .................... .................... ......mgdmannsvaysgv knslkeanhdgdFgitlaeL ralmelrstd...alrkiqe syGdvyg..........ict kLktspneGlsg.npad..l erReavfGkNfippkkpktF lqlvWeAlqDvTLiILeiaA ivSlglsfyqppegdnal.. .............cgevsvg ee.egegetGwieGaaIlls vvcVvlVTAfnDwskekQFr gLqsrieqeqkftViRgGqv iqipvaditVGDiaqvkyGD llPADGilIqgndlkiDESS lTGESdhvkksldk...... .................... ........dPlLlSGThVme Gs.grMvvTaVGvnsqtGii ftllgaggeeeekkdekkke kknkkqdgaienrnkakaqd gaamemqplkseeggdgdek d.........kkkanlpkke ksvLQgkLtklAvqIGkaGl lmsaitviiLvlyfvidtfw vqkrpwl............. ...............aectp iyiqyfvkf....fiigVTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTmNrMt VVqayinekhyk........ .......kvpepeaippnil sylvtgIsvNcaytskilpp eke................. .................... .......gglprhvGnkTEc alLgllld.Lkr....dyqd vRneipe....ealykvytF nSvrKsMstvlknsdgs... ..yRifsKGASEIiLkkCfk ilsanGeakvfrprdrddiv ktvIepmAsegLRticlAfr dfpagep............. .epewdnendivtgltciav vGIeDPvRPeVpdaikkCqr AGItVRMVTGDNinTArAIA tkCGIlh...pgedflclEG kdFnrrirnEkg........ .................... eieqeridkiwPklrVlARS sPtDKhtLVkgiidstvsdq rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNlIMDTlasLALAT EpPt.esLllRkPyGRnkpl IsrtMmkNIlghafYQlvvv ftLlfaGe.kffdidsgrna pl.................. .................... ...................h appsehyTivFNtFVlmQlF NEiNaRkihg.......... ....erNvFeGifn...... ..NaiFctivlgTfvvQiiI vqFgGkpfScseLs...... ...ieqWlwsiflGmgtllw gqlistIPtsrlkflkeagh gt.......qkeeipeeela edveeidhaerelrr.gqil wfrglnriqtqirvvnafrs slye.glekpesrssihnfm thpefriedsephipliddt daeddaptkrnsspppspnk nnnavdsgihltiemnksat ssspgsplhsletsl..... .................... .................... ........
 (124) Q00804    Oryctolagus cuniculus     ATP2B1 / PMCA1        .................... .................... .................... .................... .................... ......mgdmannsvvyggv knslkeanhdgdFgitlaav ralmelrstd...alrkile syGdvyg..........ict kLktspneGlrg.npad..l erReavfGkNfippkkpktF lqlvWeAlqDvTLiILeiaA ivSlglsfyqppegdnal.. .............cgevsvg ee.egegetGwieGaaIlls vvcVvlVTAfnDwskekQFr gLqsrieqeqkftViRgGqv iqipvsditVGDiaqvkyGD llPADGilIqgndlkiDESS lTGESdhVkKsldk...... .................... ........dPlLlSGThVme Gs.grMvvTaVGvnsqtGii ftllgaggeeeekkdekkke kknkkqdgaienrnkakaqd gepmemqplkseeggdgdek d.........kkkanlpkke ksvLQgkLtklAvqIGkaGl lmsaitviilvlyflidtfw vqkrpwl............. ...............aectp iyiqyfvkf....fiigVTv lVVAVPEGLPLpVTisLAys vneMMkDnnLVRhLdACETM GnATaICSDKTGTLTmNrMa VVqayinekhyk........ .......kvpepepyppnil sylvtgIsvNcaytskilpp eee................. .................... .......gglprivGnkTEc alLgplld.Lkq....dyqd vRneipe....ealykvytF qSvrKsMstvlknsdgs... ..fRifsKGASEIiLkkCfk ilsanGeakvfrprdrddiv ktvIepmAsegLRticlAfr dfpagep............. .epewdnendivtgltciav vGIeDPgRPeVadaikkCqr AGItVevVTGDNinTArAIA tkCGIlh...pgedflclEG kdFnrrirnEkg........ .................... eieqesidkiwPklrVlARS sPtDKhtLVkgiidstvseq rqVVAVTGDGTNDgPALkkA DgGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YDsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNLIMDTLasLALAT EpPt.esLllgkPyGRnkpl IsrtMmkNIlghafYQlvvv ftLllaGe.kffdidsgrna pl.................. .................... ...................h appsehyTivFNiFVlmQlF NEiNaRkihg.......... ....erNvFeGifn...... ..NaiFctivlgTfvvQiiI vqFaGkpfScseLs...... ...veqWlwsiflGmgtllw gqlistIPtsrlkfqkevvh gt.......qkreigeeela edveeivhaerelrr.wqil wfrglnriqtqirvvnafrs slye.glekpesrssihnfm thpefriedsephipliddt daeddaptkrnsspppspnk nnnlvdsgihltiemnksat ssspgsplhsletsl..... .................... .................... ........
 (124) P11505    Rattus norvegicus         ATP2B1 / PMCA1        .................... .................... .................... .................... .................... ......mgdmannsvaysgv knslkeanhdgdFgitlaeL ralmelrstd...alrkiqe syGdvyg..........ict kLktspneGlsg.npad..l erReavfGkNfippkkpktF lqlvWeAlqDvTLiILeiaA ivSlglsfyqppegdnal.. .............cgevsvg ee.egegetGwieGaaIlls vvcVvlVTAfnDwskekQFr gLqsrieqeqkftViRgGqv iqipvaditVGDiaqvkyGD llPADGilIqgndlkiDESS lTGESdhvkksldk...... .................... ........dPlLlSGThVme Gs.grMvvTaVGvnsqtGii ftllgaggeeeekkdekkke kknkkqdgaienrnkakaqd gaamemqplkseeggdgdek d.........kkkanlpkke ksvLQgkLtklAvqIGkaGl lmsaitviiLvlyfvidtfw vqkrpwl............. ...............aectp iyiqyfvkf....fiigVTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTmNrMt VVqayinekhyk........ .......kvpepeaippnil sylvtgIsvNcaytskilpp eke................. .................... .......gglprhvGnkTEc alLgflld.Lkr....dyqd vRneipe....ealykvytF nSvrKsMstvlknsdgs... ..fRifsKGASEIiLkkCfk ilsanGeakvfrprdrddiv ktvIepmAsegLRticlAfr dfpagep............. .epewdnendvvtgltciav vGIeDPvRPeVpeaikkCqr AGItVRMVTGDNinTArAIA tkCGIlh...pgedflclEG kdFnrrirnEkg........ .................... eieqeridkiwPklrVlARS sPtDKhtLVkgiidstvseq rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNlIMDTlasLALAT EpPt.esLllRkPyGRnkpl IsrtMmkNIlghafYQlvvv ftLlfaGe.kffdidsgrna pl.................. .................... ...................h appsehyTivFNtFVlmQlF NEiNaRkihg.......... ....erNvFeGifn...... ..NaiFctivlgTfvvQiiI vqFgGkpfScseLs...... ...ieqWlwsiflGmgtllw gqlistIPtsrlkflkeagh gt.......qkeeipeeela edveeidhaerelrr.gqil wfrglnriqtqmdvvnafqs ..............ggsiqg alrrqpsiasqhhdvtnvst pthvvfss............ .................sta stpvgypsgecis....... .................... .................... ........
 (124) P23220    Sus scrofa                ATP2B1 / PMCA1        .................... .................... .................... .................... .................... ......mgdmannsvayggv knslkeanhdgdFgitladv ralmelrstd...alrkiqe syGdvyg..........ict rLktspveGlsg.npad..i erReavfGkNfippkkpktF lqlvWeAlqDvTLiILeiaA ivSlglsfyqppegdnal.. .............cgevsvg ee.egegetGwieGaaIlls vvcVvlVTAfnDwskekQFr gLqsrieqeqkftViRgGqv iqipvaditVGDiaqvkyGD llPADGilIqgndlkiDESS lTGESdhvkksldk...... .................... ........dPlLlSGThVme Gs.grMvvTaVGinsqtGii ftllgaggeeeekkdekkke kknkkqdgaienrnkakaqd gaamemqplkseeggdgdek d.........kkkanlpkke ksvLQgkLtklAvqIGkaGl lmsaitviiLvlyfvidtfw vqkrpwl............. ...............aectp iyiqyfvkf....fiigVTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTmNrMt VVqayinekhyk........ .......kipepeaippnil sylvtgIsvNcaytskilpp eke................. .................... .......gglprhvGnkTEc alLgllld.Lkr....dyqd vRneipe....ealykvytF nSvrKsMstvlknsdgs... ..yRifsKGASEIiLkkCfk ilsanGeakvfrprdrddiv ktvIepmAsegLRticlAfr dfpagep............. .epewdnendivtgltciav vGIeDPvRPeVpdaikkCqr AGItVRMVTGDNinTArAIA tkCGIlh...pgedflclEG kdFnrrirnEkg........ .................... eieqeridkiwPklrVlARS sPtDKhtLVkgiidstvsdq rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNlIMDTlasLALAT EpPt.esLllRkPyGRnkpl IsrtMmkNIlghafYQlvvv ftLlfaGe.kffdidsgrna pl.................. .................... ...................h appsehyTivFNtFVlmQlF NEiNaRkihg.......... ....erNvFeGifn...... ..NaiFctivlgTfvvQiiI vqFgGkpfScseLs...... ...ieqWlwsiflGmgtllw gqlistIPtsrlkflkeagh gt.......qkeeipeeela edveeidhaerelrr.gqil wfrglnriqtqirvvnafrs slye.glekpesrssihnfm thpefriedsephipliddt daeddaptkrncspppspnk nnnavdsgiyltiemnksat ssspgsplhsletsl..... .................... .................... ........
  125  Q16720    Homo sapiens              ATP2B3 / PMCA3        .................... .................... .................... .................... .................... ......mgdmanssiefhpk pqqqrdvpqaggFgctlaeL rtlmelrgae...alqkiee ayGdvsg..........lcr rLktspteGlad.ntnd..l ekRrqiyGqNfippkqpktF lqlvWeAlqDvTLiILevaA ivSlglsfyappgeesea.. .............cgnvsgg aedegeaeaGwieGaaIlls vicVvlVTAfnDwskekQFr gLqsrieqeqkftViRnGql lqvpvaalvVGDiaqvkyGD llPADGvlIqandlkiDESS lTGESdhvrksadk...... .................... ........dPmLlSGThVme Gs.grMvvTaVGvnsqtGii ftllgaggeeeekkdkkgkq qdgamessqtk...akkqdg avamemqplksaeggemeer e.........kkkanapkke ksvLQgkLtklAvqIGkaGl vmsaitviiLvlyfvietfv vegrtwl............. ...............aectp vyvqyfvkf....fiigVTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTtNrMt VVqsylgdthyk........ .......eipapsaltpkil dllvhaIsiNsayttkilpp eke................. .................... .......galprqvGnkTEc alLgfvld.Lkr....dfqp vReqipe....dklykvytF nSvrKsMstvvrmpdgg... ..fRlfsKGASEIlLkkCtn ilnsnGelrgfrprdrddmv rkiIepmAcdgLRticiAyr dfyag.q............. .epdwdnenevvgdltciav vGIeDPvRPeVpeairkCqr AGItVRMVTGDNinTArAIA akCGIiq...pgedflclEG keFnrrirnEkg........ .................... eieqerldkvwPklrVlARS sPtDKhtLVkgiidsttgeq rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNlIMDTfasLALAT EpPt.esLllRkPyGRdkpl IsrtMmkNIlghavYQlaii ftLlfvGe.lffdidsgrna pl.................. .................... ...................h sppsehyTiiFNtFVmmQlF NEiNaRkihg.......... ....erNvFdGifs...... ..NpiFctivlgTfgiQivI vqFgGkpfScspLs...... ...teqWlwclfvGvgelvw gqviatIPtsqlkclkeagh gp.......gkdemtdeela egeeeidhaerelrr.gqil wfrglnriqtqmevvstfkr sgsvqgavr..rrssvlsql hdvtnlstpthailsaanpt saagnpggesvp........ .................... .................... .................... .................... ........
 (125) Q64568    Rattus norvegicus         ATP2B3 / PMCA3        .................... .................... .................... .................... .................... ......mgdmanssiefhpk pqqqrevphvggFgctlaeL rslmelrgae...alqkiqe ayGdvsg..........lcr rLktspteGlad.ntnd..l ekRrqiyGqNfippkqpktF lqlvWeAlqDvTLiILevaA ivSlglsfyappgeesea.. .............cgnvsgg aedegeaeaGwieGaaIlls vicVvlVTAfnDwskekQFr gLqsrieqeqkftViRnGql lqvpvaalvVGDiaqvkyGD llPADGvlIqgndlkiDESS lTGESdhvrksadk...... .................... ........dPmLlSGThVme Gs.grMvvTaVGvnsqtGii ftllgaggeeeekkdkk... ..............akkqdg avamemqplksaeggemeer e.........kkkanvpkke ksvLQgkLtklAvqIGkaGl vmsaitviiLvlyfvietfv vdgrvwl............. ...............aectp vyvqyfvkf....fiigVTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTtNrMt VVqsylgdthyk........ .......eipapsaltpkil dllvhaIsiNsayttkilpp eke................. .................... .......galprqvGnkTEc alLgfild.Lkr....dfqp vReqipe....dqlykvytF nSvrKsMstvirmpdgg... ..fRlfsKGASEIlLkkCtn ilnsnGelrgfrprdrddmv kkiIepmAcdgLRticiAyr dfsai.q............. .epdwdnenevvgdltciav vGIeDPvRPeVpeairkCqr AGItVRMVTGDNinTArAIA akCGIiq...pgedflclEG keFnrrirnEkg........ .................... eieqerldkvwPklrVlARS sPtDKhtLVkgiidsttgeq rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNlIMDTfasLALAT EpPt.esLllRkPyGRdkpl IsrtMmkNIlghavYQltii ftLlfvGe.lffdidsgrna pl.................. .................... ...................h sppsehyTiiFNtFVmmQlF NEiNaRkihg.......... ....erNvFdGifs...... ..NpiFctivlgTfgiQivI vqFgGkpfScspLs...... ...teqWlwclfvGvgelvw gqviatIPtsqlkclkeagh gp.......gkdemtdeela egeeeidhaerelrr.gqil wfrglnriqtqmevvstfkr sgsfqgavr..rrssvlsql hdvtnlstpthvtlsaakpt saagnpsgesip........ .................... .................... .................... .................... ........
  126  Q01814    Homo sapiens              ATP2B2 / PMCA2        .................... .................... .................... .................... .................... ......mgdmtns..dfysk .nqrnesshggeFgctmeeL rslmelrgte...avvkike tyGdtea..........icr rLktspveGlpg.tapd..l ekRkqifGqNfippkkakpF lqlvWeAlqDvTLiILeiaA iiSlglsfyhppgegneg.. .............cataqgg aedegeaeaGwieGaaIlls vicVvlVTAfnDwskekQFr gLqsrieqeqkftVvRaGqv vqipvaeivVGDiaqvkyGD llPADGlfIqgndlkiDESS lTGESdqvrksvdk...... .................... ........dPmLlSGThVme Gs.grMlvTaVGvnsqtGii ftllgaggeeeekkdkk... ..............akqqdg aaamemqplksaeggdadd. ..........rkkasmhkke ksvLQgkLtklAvqIGkaGl vmsaitviiLvlyftvdtfv vnkkpwl............. ...............pectp vyvqyfvkf....fiigVTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTtNrMt VVqayvgdvhyk........ .......eipdpssintktm ellinaIaiNsayttkilpp eke................. .................... .......galprqvGnkTEc glLgfvld.Lkq....dyep vRsqmpe....eklykvytF nSvrKsMstviklpdes... ..fRmysKGASEIvLkkCck ilngaGeprvfrprdrdemv kkvIepmAcewLRticvAyr dfpss.p............. .epdwdnendilneltcicv vGIeDPvRPeVpeairkCqr AGItVRMVTGDNinTArAIA ikCGIih...pgedflclEG keFnrrirnEkg........ .................... eieqeridkiwPklrVlARS sPtDKhtLVkgiidsthteq rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFssIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNlIMDTfasLALAT EpPt.etLllRkPyGRnkpl IsrtMmkNIlghavYQlali ftLlfvGe.kmfqidsgrna pl.................. .................... ...................h sppsehyTiiFNtFVmmQlF NEiNaRkihg.......... ....erNvFdGifr...... ..NpiFctivlgTfaiQivI vqFgGkpfScspLq...... ...ldqWmwcifiGlgelvw gqviatIPtsrlkflkeagr lt.......qkeeipeeeln edveeidhaerelrr.gqil wfrglnriqtqirvvkafrs slye.glekpesrtsihnfm ahpefriedsqphipliddt dleedaalkqnssppsslnk nnssidsginlttdtsksat ssspgspihsletsl..... .................... .................... ........
 (126) O88863    Mus musculus              ATP2B2 / PMCA2        .................... .................... .................... .................... .................... ......mgdmtns..dfysk .nqrnesshggeFgctmeeL rslmelrgte...avvkike tyGdtea..........icr rLktspveGlpg.tapd..l ekRkqifGqNfippkkpktF lqlvWeAlqDvTLiILeiaA iiSlglsfyhppgesneg.. .............cataqgg aedegeaeaGwieGaaIlls vicVvlVTAfnDwskekQFr gLqsrieqeqkftVvRaGqv vqipvaeivVGDiaqikyGD llPADGlfIqgndlkiDESS lTGESdqvrksvdk...... .................... ........dPmLlSGThVme Gs.grMvvTaVGvnsqtGii ftllgaggeeeekkdkk... ..............akqqdg aaamemqplksaeggdadd. ..........kkkanmhkke ksvLQgkLtklAvqIGkaGl vmsaitviiLvlyftvdtfv vnkkpwl............. ...............tectp vyvqyfvkf....fiigVTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTtNrMt VVqayvgdvhyk........ .......eipdpssinaktl ellvnaIaiNsayttkilpp eke................. .................... .......galprqvGnkTEc glLgfvld.Lrq....dyep vRsqmpe....eklykvytF nSvrKsMstvikmpdes... ..fRmysKGASEIvLkkCck ilsgaGearvfrprdrdemv kkvIepmAcdgLRticvAyr dfpss.p............. .epdwdnendilneltcicv vGIeDPvRPeVpeairkCqr AGItVRMVTGDNinTArAIA ikCGIih...pgedflclEG keFnrrirnEkg........ .................... eieqeridkiwPklrVlARS sPtDKhtLVkgiidsthteq rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFssIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNlIMDTfasLALAT EpPt.etLllRkPyGRnkpl IsrtMmkNIlghavYQltli ftLlfvGe.kmfqidsgrna pl.................. .................... ...................h sppsehyTiiFNtFVmmQlF NEiNaRkihg.......... ....erNvFdGifr...... ..NpiFctivlgTfaiQivI vqFgGkpfScspLq...... ...ldqWmwcifiGlgelvw gqviatIPtsrlkflkeagr lt.......qkeeipeeeln edveeidhaerelrr.gqil wfrglnriqtqirvvkafrs slye.glekpesrtsihnfm ahpefriedsqphipliddt dleedaalkqnssppsslnk nnsaidsginlttdtsksat ssspgspihsletsl..... .................... .................... ........
 (126) P11506    Rattus norvegicus         ATP2B2 / PMCA2        .................... .................... .................... .................... .................... ......mgdmtns..dfysk .nqrnesshggeFgcsmeeL rslmelrgte...avvkike tyGdtes..........icr rLktspveGlpg.tapd..l ekRkqifGqNfippkkpktF lqlvWeAlqDvTLiILeiaA iiSlglsfyhppgesneg.. .............cataqgg aedegeaeaGwieGaaIlls vicVvlVTAfnDwskekQFr gLqsrieqeqkftVvRaGqv vqipvaeivVGDiaqikyGD llPADGlfIqgndlkiDESS lTGESdqvrksvdk...... .................... ........dPmLlSGThVme Gs.grMvvTaVGvnsqtGii ftllgaggeeeekkdkk... ..............akqqdg aaamemqplksaeggdadd. ..........kkkanmhkke ksvLQgkLtklAvqIGkaGl vmsaitviiLvlyftvdtfv vnkkpwl............. ...............tectp vyvqyfvkf....fiigVTv lVVAVPEGLPLAVTisLAys vkKMMkDnnLVRhLdACETM GnATaICSDKTGTLTtNrMt VVqayvgdvhyk........ .......eipdpssinaktl ellvnaIaiNsayttkilpp eke................. .................... .......galprqvGnkTEc glLgfvld.Lrq....dyep vRsqmpe....eklykvytF nSvrKsMstvikmpdes... ..fRmysKGASEIvLkkCck ilsgaGeprvfrprdrdemv kkvIepmAcdgLRticvAyr dfpss.p............. .epdwdnendilneltcicv vGIeDPvRPeVpeairkCqr AGItVRMVTGDNinTArAIA ikCGIih...pgedflclEG keFnrrirnEkg........ .................... eieqeridkiwPklrVlARS sPtDKhtLVkgiidsthteq rqVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFssIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi vaFtgacitqds........ ................PLkA VQmLWVNlIMDTfasLALAT EpPt.etLllRkPyGRnkpl IsrtMmkNIlghavYQltli ftLlfvGe.kmfqidsgrna pl.................. .................... ...................h sppsehyTiiFNtFVmmQlF NEiNaRkihg.......... ....erNvFdGifr...... ..NpiFctivlgTfaiQivI vqFgGkpfScspLq...... ...ldqWmwcifiGlgelvw gqviatIPtsrlkflkeagr lt.......qkeeipeeeln edveeidhaerelrr.gqil wfrglnriqtqirvvkafrs slye.glekpesrtsihnfm ahpefriedsqphipliddt dleedaalkqnssppsslnk nnsaidsginlttdtsksat ssspgspihsletsl..... .................... .................... ........
  127  O45215    Caenorhabditis elegans    mca-1 / W09C2.3       .................... .................... .................... .................... .................... .................mrl rrghtydedakeFgcslgdL rglmeargae...aivrlst ehegveg..........lck kLktdslvGlng.eqad..l drRrhvyGaNtippakskgF vrlvldAckDpTLvILvlsg finlalsfyeptsaaedatq hlvnattaailangtfmstt eapseghgtawieGvaIllc vivVvlVTAvnDyskerQFr sLqekietgqkfsViRnGea idvpvsdlvVGDiarvkyGD llPADGflIqsndlkiDESS lTGESdhikksies...... .................... ........dPvLlSGTyame Gs.gkMliTaVGvnsqtGii mtllgagkagigdddst... ..............stssss sssssssgsssngssdss.. ...........ksgdddlta ksvLQakLsklAlqIiycGt tiaiialivLvtrfcldhyv fekn................ ................efsl vdiqmfvkf....fiiaVTi lVisiPEGLPLAialaLtys vrKMMhDnnLVRhLdACETM GnATsICSDKTGTLTtNrMt VVqsyingnhytsqe..... .......aqphganlpgstg pilmeaIsvNcaynsmivep tka................. .................... .......geqiqqlGnkTEc glLgfvnr.Lgg....dyaa iRkkfpe....hdltkvytF nSsrKcMmtvvpyaengqni .gyRvycKGASEIvLgrCty ligsdGkphqltgdrlkeit stiIhemAnsgLRticvAyk tiikkgtrdvekteiefaed sdidwddedamyqnftgiai cGIqDPvRPeVpvaiskCkk AGItVRMVTGDNimTArAIA msCkIle...pgedflalEG keFnerirdEng........ .................... kvsqakldeiwPrlrVlARa qPaDKytLVkgiidskatpq reiVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YdsIsKFlQFQLTVNVvAvi taFvgavtvsds........ ................PLkA VhmLWiNlIMDTlasLALAT EqPt.deLleRkPyGRkksl IsrtMvkNIlchalYQliii fviffyGd.tifgiktglya pl.................. .................... ...................f appsqhfTlvFNaFVmmtvF NEiNaRkvhg.......... ....erNvFkGlas...... ..NrvFcviwvtTfiaQiiI vqFgGawfStapLt...... ...lqqWivclvlGfstliw gqivatIPskklpkawkvgk ge........vqpanlhing dynvrarsravtlrrsgksl wvrgmfiignhlrvlrafgm eksekaafgrtapamtaeaa erwrasyrkyrhqkhqekka taetaesvksadwakeqkek kktfkqikqvargksldkds kkhhkkrkdqtnvdmediel n................... .................... ........
   -   O76833    Caenorhabditis elegans    mca-2 / R05C11.3      .................... .................... .................... .................... .................... .................... ......mpssddydcsiseL kllmelrgae...alekvns tyngveg..........lcr kLktdpinGlpn.dtke..l ehRrtafGkNeippapsksF frlaWeAlqDiTLvILlvaA lvSlglsfykppaehas... .................... .ndsseseaGwieGvaIlva vlvVvlVTAlnDwtkekQFr gLqskietehkfsViRgGep ldivvnelvVGDiarvkyGD llPADGllIqsndlkiDESS lTGESdlirkseef...... .................... ........dPvLlSGThame Gs.grflvTaVGlnsqtGii msllgaakekkddkkee... ..............pttltn gnhmnglgngvdkaaelp.. .........vpeeeevgrms ksvLQtkLsnlAlqIGyiGs ivaaatvliLiirhciskya iegk................ ................sfea sdishfvnf....iiigVTv lViAVPEGLPLAiTlaLtys vkKMMknnnLVRhLdACETM GnATsICSDKTGTLTtNrMt cVqqyinsefykg....... .......napkyeqmdpstr dilfngIviNsgynstvvtp knp................. .................... .......geqrgqiGnkTEc slLgfimd.sgr....syed lRrqfpe....eklykvytF nSsrKsMmtvielgdkk... ..yRiyaKGASEIiLtrCny ifgksGkieqfgpkeaavmt knvIepmAsdgLRtiglAfk dlvpags...kkyeyeeeyd geidwedeekiregqtviav mGIqDPvRPeVpaaiakCqk AGItVRMVTGDNinTArsIA tqCGImq...pggdflalEG keFnarirdadg........ .................... kvnqqkfdaiwPklrVlARa qPsDKyvLVkgiiestvtkn reVVAVTGDGTNDaPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFssIVkavmWGRnV YdsIaKFlQFQLTVNVvAvt iaFigacaisds........ ................PLkA VQmLWVNlIMDTlasLALAT EmPt.edLlnRkPyGRtksl IsrtMvkNIvghavYQlail faimfwGdklipntpsgrna el.................. .................... ...................g sppsahfTiiFNaFVlmtlv NEiNaRkihg.......... ....erNvFkGift...... ..NpiFcviwitTlishilI vqFgGqwfStapLd...... ...ltqWiiciccGvgelfw gqiincIPasilpksfrfgk gdvqptsimlsgeydmpsta stlpmkdgaaadhqragqsl wllgltrlqtqirvvkafqs vnddshpnslttstadrlra syrrlriareleqqkraggl rasgqvystetnakdtsgir fa.................. .................... .................... .................... ........
   -   O76832    Caenorhabditis elegans    mca-3 / Y67D8A_367.a  .................... .................... .................... .................... .................... .................... ......mp...eygasleeL ralmeyrsae...akekiet dyGgttg..........lce rLktdpnnGlpn.neee..l erRrnvfGaNeipphppkcF lqlvWeAlqDvTLvILlvsA ivSlalsfyrppgedtag.. .................... .sddsehdaGwieGvaIlis vivVvlVTAlnDytkerQFr gLqakietehrffVlRgGqs vqvvvnelvVGDiaqikyGD liPsDGiiIqsndlkmDESS lTGESdqirkspeh...... .................... ........dPiilSGThVme Gs.gkMlvTaVGvnsqtGii mtllgaaktvaeeerk.... ..............takreg gdgasgaeegtaqalldskg deamangkavaaaesdgkke rsvLQakLtrlAiqIGyaGs fvagctvliLiirfcisrya idgk................ ................sfsl adfqhfinf....liigVTv lVVAVPEGLPLAVTlsLAys vkKMMlDnnLVRhLdACETM GnATaICSDKTGTLTtNrMt VVqsfvndvhyk........ .......dtpkiesldqnta klmmdcIsiNssyssqvipp kql................. .................... .......geqatqlGnkTEc gmLgfvla.Lgk....syqe iRdrhpe....etipkvytF nSvrKsMstvinlpdgg... ..yRvfsKGASEIvtkrCky flgknGtltkfsskdaenlv rdvIepmAsdgLRticvAyk dyvpssk...ktadnqiays sepdweneemivgdmtaiav lGIqDPvRPeVpaaitrCqe AGItVRMVTGDNinTArsIA taCGIlk...pgedfialEG keFnarirdEng........ .................... evsqekldliwPklrVlARa qPsDKyvLVkgiidsrvtds reVVAVTGDGTNDgPALkkA DvGfAMGIaGTdVAKEasDi IltDDNFtsIVkavmWGRnV YdsIaKFlQFQLTVNVvAvv vaFvgacaiqdt........ ................PLkA VQmLWVNlIMDTlasLALAT EmPt.eeLlkRkPyGRtspl IsrtMckyIlghavYQlvil ftLifyGe.vcfnipsgrwa pl.................. .................... ...................h sppskhfTivFNtFVmmtlF NEiNaRkihg.......... ....erNiFkGlfs...... ..NpiyyviwiaTmisQvvI iqFgGrwfStsaLn...... ...tteWlwclafGvgtllw gqivtsIPtgslpanmtigs g.............eaptnd plmpdyedsdthekrsgqil wvrgltrlqtqlrvvkafrs sleefderrsiasthsvqsm rggfwsgggrhtttaaspep agqriamaaithrqspqpyp yyhhqqprtpspqphivven gtssgnngqaataaaaapka etngktekvplvqqwspdtn ssytqtqrtstracllilqf llltcnsf
  128  P54678    Dictyostelium discoideum  PatA                  .................... .................... .................... .................... .................... ..............mtgshe mesimldsmeeeFpvsvetL gklvdvpkg......fdtya elGglsg..........lst kLksniktGlpleksst..e enRvlkyskNilpdpphqpl wsivldAlsDhiLilLivaA vvSivlgsidyt........ .................... ...sdhpetGwidGvaIlva vilVvgiTslnDfknqarFr eLndksnd.kevkgiRgGeq cqisifdvkVGDiisldtGD iicADGvfIeghalkyDESS iTGESdpikkgqpq...... .................... .....dnmdPfLiSGsmVie Gf.gtMlvTaVGvnsfnGkt mmglrvased.......... .................... .................... .................... .tphQmkLsvlAsrIwlfGm gaailmlliaipkyfiqrkv hd.................. ...............ieitr edaqpivql....visaiTi vVVAVPEvLPLAVTmaLAyg mmKMfkennLVRnLasCETM GsATtICSDKTGTLTqNvMs VVtgticgvfptldg..... ..........iaqkipkhvq siltdgmaiNsnayegvssk .................... .................... ........gklefiGskTEc alLnfgkl.fgc....dyne vRkrl.......evvelypF sSarKrMsvlvkhdqn.... ..lRlftKGASEIiLgqCgs yldeaGnirpiseakay..f eeqInnfAsdaLRtiglAyr dfqygecdfk.......... ........eppennlvfigi vGIkDPlRPeVpeaveiCkr AGIvVRMVTGDNlvTAqnIA rnCGIlt.....egglcmEG pkFrelsqsEm......... .................... .......dvilPklqVlARS sPtDKqlLVgrlk.....dl geVVAVTGDGsNDgPALklA nvGfsMGIsGTeVAiaasDv vllDDNFasIVravlWGRni YdaIcKFlQFQLTVNVvAvt vaFigtltsdvvedkdnsss sgsadkvteeeprqgsPLtA VQlLWVNlIMDTlaaLALAT EpPt.peLleRpPnGknapl ItrsMwkNIigqaalQlail ftilyqGhnifqhfvpqahg pi.................. .................... ...................i knglhhyTlvFNcFVflQlF NEiNaRvlgs.......... ....rtNpFknffn...... ..NpiFiavmifTlgvQiif vtFgGsatStdsLy...... ...iveWiccvvvGaislpv glllrkIPirepvvkneipv hseavytspspnpsssnllg sggakpiskdyptsgestpp indegsplvtrktsvgasan dnintpipssssnlvnlnkp tqvgrgwqivrqthkklvvi nalkefsqnkepglvdvvrg tnrgslhlpvnqinn..... .................... .................... .................... ........
  129  P38929    Saccharomyces cerevisiae  PMC1 / ygl006w        .................... .................... .................... .................... .................... .msrqdensallannennkp sytgnengvydnFklsksqL sdlhnpks.......irsfv rlfgyesns........lfk yLktdknaGislpeisnyrk tnRyknyGdNslperipksF lqlvWaAfnDkTmqlLtvaA vvSfvlglyelwmqppqyd. .................... pegnkikqvdwieGvaImia vfvVvlVsAanDyqkelQFa kLnkkken.rkiiViRndqe ilisihhvlVGDvislqtGD vvPADcvmIsg.kceaDESS iTGESntiqkfpvdnslrdf kkfnsidshnhskpldigdv nedgnkiadcmLiSGsrils Gl.grgviTsVGinsvyGqt mtslnaepes.......... .................... .................... .................... .tpLQlhLsqlAdnIsvyGc vsaiilflvLftrylfyiip edgr................ ................fhdl dpaqkgskfmn.ifitsiTv iVVAVPEGLPLAVTlaLAfa ttrMtkDgnLVRvLrsCETM GsATavCSDKTGTLTeNvMt VVrgfpgnskfddskslpvs eqrklnskkvfeencssslr ndllanIvlNstafenrdyk kndkntngsknmsknlsfld kcksrlsffkkgnreddedq lfknvnkgrqepfiGskTEt alLslarlsLglqpg.elqy lRdqpmekfniekvvqtipF eSsrKwaglvvkykegknkk pfyRffiKGAaEIvsknCsy krnsddtleeinednkk.et ddeIknlAsdaLRaisvAhk dfcecdswp.peqlrdkdsp niaaldllfnsqkglildgl lGIqDPlRagVresvqqCqr AGvtVRMVTGDNilTAkAIA rnCaIlstdisseaysamEG teFrkltknEr......... .................... .......irilPnlrVlARS sPeDKrlLVetlkg.....m gdVVAVTGDGTNDaPALklA DvGfsMGIsGTeVArEasDi IlmtDdFsaIVnaikWGRcV svsIkKFiQFQLiVNitAvi ltFvssvassde........ ..............tsvLtA VQlLWiNlIMDTlaaLALAT dkPd.pnimdRkPrGRstsl IsvstwkmIlsqatlQlivt fiLhfyGpelffkkhedeit .................... .................... ...................s hqqqqlnamtFNtFVwlQfF tmlvsRkldegdgisnwrgr isaanlNfFqdlgr...... ..NyyFltimaiigscQvlI mfFgGapfSiarqt...... ...ksmWitavlcGmlslim gvlvricPdevavkvfpaaf vqrfkyvfgleflrknhtgk hddeealleesdspestafy .................... .................... .................... .................... .................... .................... .................... .................... ........
   -   O60948    Trypanosoma cruzi                               .................... .................... .................... .................... ........mrrssfsygscd emeeetkmrrsrlmesvrrr tsirvnftdgddvgvsirtd lenifaraneg....mplye klGraeg..........iaa kLqmdlnnGvrs.etve... .rRrtvfGrNelpeeeelsF wriykaAwsDqmillLsgaA fvSlvlgltvpepg...... .................... .rdkadtgtGwieGfaIlvs vliVttVssvnDyrkelkFr qLmeensa.qpiaViRgGre qvidvteivVGDivslstGl vvPvDGfyvrglsvviDESS vTGEndpkkkgvqa...... .................... .........PiLltGTvVnt aedayMlacaVGessfgGkl lmesrqeggpr......... .................... .................... .................... mtpLQerLdelAglIGrfGm gsavllfslLsllevfriir .................... ................gtde fhmktfldh....fllcVTi vVVAVPEGLPLAVTiaLAys qkKMqeDnnqVRrLcACETM GcATqICSDKTGTLTqNlMs VVqgyiglqrfnvrdpgd.. .....vptpivlrnvpaasr dllveglslNsssekvvcrt grd................. ...................g esvarpywqwradkGnkTdn alLdfvdrvLlqdgdptdmt sRphqrvragsrhgfaifpF tSerKfMsvvvagpgg..vl taaRegrvGpragnvrplrf rfgcgGgatdgcdadkd.rc adpfpplttrtaRsvwlmgv smakafp............. ........rasygaagvgca rGhsgPsaaggtrrgaevqq AGvtVRMcTGDNldTAvAIs rsahlqp....ftwrcgndr keFrslvydayg........ ...................s sanmekfwpildrmvVmARS qPlDKqlLVlmlm.....mr geVVAVTGDGTNDaPALrlA nvGfvM.rsGTdiAvkssDi vllDDNFrsvqravvWGRtV ndnIrKFlQlQLTVNVssvv ltFlgsflssshts...... ................PLst VQlLWVNlIMDTlaaLALAT EePs.eacldRgPipRkapl vsrrMwctIlaiagYQtvst llverfGg.swfdvsgg... .................... .................... .................... ....emqTivFNvFllsviF hmfNaRklye.......... ....emNcFeGlwkr..... ..sriFvcivgfcfafQvfs vemlGsfmqvvsLr...... ...geqWvgclalsfltlvf gavarlvPveelplpeaemd dmepearrmamkltadveah aaregagghlllgrrllaqa mwqqvrehhiavrsvnafrr aridrdmhtsvakdiycrla stmq................ .................... .................... .................... .................... .................... ........
Identical in 18 out of 26 sequences                              -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ------------F------L -------------------- --G----------------- -LKT----G----------L --R----G-N--P------F ---VWEALQD-TL-IL--AA --SL-L-------------- -------------------- ---------GWIEG-AIL-S V--VV-VTA-ND--K--QFR -L-----------V-R-G-- ---------VGDI-----GD --PADG--I-G--L-IDESS LTGES----K---------- -------------------- ---------P-LLSGT-V-- GS-G-M-VT-VG-NS--G-- ---L---------------- -------------------- -------------------- -------------------- ---LQ-KL--LA--IG--GL -----T---L---------- -------------------- -------------------- -------------FII-VT- -VVAVPEGLPLAVT-SLAYS -KKMM-D-NLVRHL-ACETM G-AT-ICSDKTGTLT-N-MT VV------------------ -------------------- --L---I--N---------- -------------------- -------------------- --------------G-KTE- ALL------L------D--- -R-------------K---F NS-RK-M--V---------- ---R---KGASEI-L--C-- -----G-------------- ---I---A---LRT-C-A-- D------------------- ---------------T-I-- VGI-DPVRP-V--A---C-- AGITVRMVTGDNI-TA-AIA --CGI-------------EG --F------E---------- -------------------- ---------I-PKL-V-ARS SP-DK--LV----------- --VVAVTGDGTND-PALK-A DVGFAMGIAGT-VAKEASDI IL-DDNF-SIV-AV-WGR-V Y--I-KFLQFQLTVNVVAVI --F--AC------------- ----------------PL-A VQ-LWVNLIMDT-A-LALAT EPP----L--R-P-GR---L IS--M--NILG-A-YQL--- --L-F-G----F-------- -------------------- -------------------- -------------------- -------T--FN-FV--Q-F NEIN-RK------------- ----E-NVF-G--------- --N--F--I---T---QI-I V-F-G---S---L------- -----QW------G---L-- G-----IP------------ -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- --------
Identical in 22 out of 26 sequences                              -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ------------F------L -------------------- --G----------------- -L------G----------- --R----G-N---------F ----W-A--D-TL-IL---A --S----------------- -------------------- ---------G---G--I--- ---V--VTA--D-----QF- -L-----------V-R-G-- ---------VGD------GD --PADG--I-------DESS -TGES--------------- -------------------- ---------P-L-SGT-V-- G----M--T-VG-----G-- -------------------- -------------------- -------------------- -------------------- ---LQ--L---A--IG--G- ---------L---------- -------------------- -------------------- -----------------VT- -VVAVPEGLPLAVT--LA-- --KMM-D--LVR-L-ACETM G-AT-ICSDKTGTLT-N-M- VV------------------ -------------------- ------I--N---------- -------------------- -------------------- --------------G--TE- --L------L---------- -R-----------------F -S--K-M------------- ---R---KGASEI-L--C-- -----G-------------- ---I---A---LR----A-- -------------------- -------------------- -GI-DP-RP-V------C-- AGI-VRMVTGDN--TA-AIA --CGI-------------EG --F------E---------- -------------------- -----------P---V-ARS -P-DK--LV----------- --VVAVTGDGTND-PAL--A D-G-AMGI-GT-VAKE--D- I--DDNF--IV----WGR-V Y--I-KF-QFQLTVNV-A-- --F----------------- ----------------PL-A VQ-LWVN-IMDT---LALAT E-P----L--R-P-GR---- I---M--NI-----YQ---- --L---G------------- -------------------- -------------------- -------------------- -------T--FN-FV--Q-F NE-N-R-------------- ------N-F-G--------- --N--F------T---Q--I --F-G---S---L------- ------W------G------ ------IP------------ -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- --------
Identical in all 26 sequences                                    -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- ---------N---------- ------A--D-----L---- -------------------- -------------------- -------------G--I--- -----------D------F- -L-------------R---- ----------GD------G- ----D--------------S --GE---------------- -------------------- --------------G----- ----------VG-----G-- -------------------- -------------------- -------------------- -------------------- ----Q--L---A--I---G- -------------------- -------------------- -------------------- -------------------- -----PE-LPL-----L--- ----------VR----CETM ------C-DKTGTLT-N-M- -------------------- -------------------- ---------N---------- -------------------- -------------------- --------------G--T-- --L----------------- -------------------F -S--K--------------- --------G----------- -------------------- ------------R------- -------------------- -------------------- -G------------------ AG--V----GDN--TA--I- -------------------- --F----------------- -------------------- ---------------V--R- -P-DK--------------- ---VAVTGDG-ND-PAL--- --G--M---GT--A------ ----D-F----------R-- ---I-KF-Q-QL-VN----- -------------------- -----------------L-- ---LW-N-IMD----LAL-T ------------P------- ---------------Q---- -------------------- -------------------- -------------------- -------------------- ----------FN-F------ -------------------- --------F----------- -------------------- -------------------- ------W------------- -------P------------ -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- -------------------- --------
Conserved segments in all P type ATPases                                                                                                                                                                                                                                                                                                                                                                                                 aaaaaaaaaaaaaaaaa aaaaaaaa       bbbbb bbbbbbbbbbbbbb                                        cccccccc ccccccccccccccccccc                                                                                                                                                                                       ddddddd ddddddddddddddddd           eeeeeeeeeeeee eeeeeeeeeeeeeeeeeeee eee                                                                                                                                                                                                                                                                                       fffffffffff ffffffffffffffffffff ffffffffffffffffffff ffffff                                                                        ggggg gggggggggggggggggggg gggggggggggggggggggg gggggg   hhhhhhhhhhh hhhhhhhhhhhhhhhhhhhh
Transmembrane helices                                                                                                                                                                                                                                                                                 1 11111111111111111111                                                       22222222 2222222222222                                                                                                                                                                                                                                                       333333333333 33333333                                                                    4444444 44444444444                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                5555555555555555 5555                                   66 6666666666666666666                       77777777777777777777 777                                                                               8 88888888888888888888 8                                           999999999999999999 9999                    00000000000000000 00000



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