Alignment of alpha subunits of P2C ATPases (Na+/K+ + H+/K+)

The alignment was performed on The Danish Biotechnological Database with the programme CLUSTALW with default settings. The alignment of the N- and C-termini was refined by hand.
The grouping of P-type ATPases and the nomenclature is adopted from the work described in Axelsen, K.B. & Palmgren, M.G. (1998) J. Mol. Evol. 46: 84-101.
The sequence numbers refer to the position of the sequence in a phylogenetic tree of P-type ATPases.
The sequences with sequence numbers in parantheses are not included in the phylogenetic tree, but show more than 90 % sequence identity with the sequence with the specified number.
The positions of the transmembrane helices are determined via the crystal structure of rabbit SerCa1. The borders of transmembrane helices might change by one or two amino acids.
The segments a-h conserved in all P-type ATPases are the amino acid stretches used for the phylogenetic analysis.
Amino acids in the alignment shown in CAPITALS are present in at least 84% (37 of 44) of theP2C ATPases . 
Number Accession    Organism                  Name
used   number                                                1                                                                                                    100 101                                                                                                  200 201                                                                                                  300 301                                                                                                  400 401                                                                                                  500 501                                                                                                  600 601                                                                                                  701 701                                                                                                  800 801                                                                                                  900 901                                                                                                 1000 1001                                                                                                1100 1101                                                                           1180
   97  Q95024    Dictyostelium discoideum   IonA             .................... .................... .......aseydvnehEltl eqisekfstninsndpslss GLtqslAnelLirnGkNiLk PPkevPwyvqlgkcftnffm iLlevagalCflAygldrnq r.......vNLYLacvLyai VifTclltfsQErqtgnImk SFknllPQscrViRdGsetk vkvediVvGDiVmcqaGDkv PADiRiitcngmKVDNSSLT GESdaQsctvtcTddnP..L EThNlaFcgTlvmdGsarGv VirtGsnTliGkIAdLASnt eqteTtlqiEIkrFvhfIta lgitmGliFFiigfavg... idsiqnlinvlgliVAnVPE GLpsTiTacLtvTArRlsrr NvysKkLEsiETLGSitlIa SDKTGTLTQNRMTVsHmWyD ntIvrAiengg........t igrqlfdigtptcaaLlnvg acCNRAdFdr.......... .....llegnmerPienrli lGDASEsAiLrlchtiedi. ..eitRaknpKvfEIPFNST NKwQlSIHklpndqpqsn.. ....tstarilyMKGAPEii fekCSklmi.nGkEleiDek ikndFiqAYeaLGsmGERcL GFaqllLdnentvpndmyda qtl.NFPmtgLtFvGLcSll DPPRenVPfAVhqCktAGIk VIMVTGDHPITAKAIAkkVG IIS..spTaEDIAlergipl sqVdd......nevkAvVlh GgqireltdadwdrvLs.ks EIVFARTSPQQKsqIVEnaQ krkevVAVTGDGVNDSPALK KADIGvAMGIvGSDvaKetA DiILLDDNFASIVaGiEEGR iIFDNLKKSIAYTLshavPE vaPfLlnIisgiPLaitsfl ILcIDLgTemaPaiSLAYEt gEkDIMsrk.PRvlgkDh.. .................... .................... ...................L VttnLlsysYlQaGpieaii sFlnfFlvlAhhG....... .fpPhsLpgttndyffegcg kylgfesdyqvealR..... qaqTayFmtlvtcQffnLit nrTRvvplwshkilsNwyin iglvieagicafvvYtPfvh tiiesasv.pglfWayplPm ifclfswnEiRkriaydrPd w.kissslgf.......... 
   -   O16436    Caenorhabditis elegans     C02E7.1          ...............mtllf gvkrwlrrgdeasdskadas kevnqqnlslsfnehhldmr qlsekfsmskldivdpkvsr GLskqvAaerLesDGrNaLs PPkvisnwklFlrqfknllw iLmfgaAalslvAyiydpsd l.......tNLcvgifiivi ifvmcivsffeEkKgvevvr aFqslmPlscqViRdGveqt lnpeelVvGDiVvvrsGckv PADiRviactdfyletSSiT GEaEPlefnsamadqktsif EsyNiaFngsfcvdGegyGi VirtGerTviGqIAsmtldq keqkckfqvEIgrFvkfItv mAiimaviiFsvglginkgh dviryfvtgflmviiAnVPq GLptTVTteLtiiArRmAkK NvflKkLEkidsvGaTtlIa SDKTGTLTkNcMTVtdlWyn nsynsgrpenrrrstktrfs itsnpaqsfdaplsdLlsvv cvCNkArientvtvnrpppn vdseldmsmyriqPvkemti vGnpSEvALLryasamlda. ..kelResfqvvfEIPFNSv rKyhlilatnkntwnqvd.k ...nddvefvvmiKGAPEvl iknCStmni.nGeskeLDlk rmedFneAYeafGdeGcRVi GFaqkkfrar...astvFsl ksn.tvPmedwdFlGmsaim DPPRddtPkAikaCkaAGIk VyMVTGDHksTAtAIArqiG mId..tEeVsrvdhnqqiir rsnsq........d.waVit GseLpaltqkqwdelLq.hr yIVFARTtPehKLmIVtesQ krGecVtVTGDGVNDaPALK KADvGvAMGlaGSDvaKqAA DiILLDDNFsSIVaGiEEGR LlFDNLrKtIAYTmahmwPE lvPvilnfffgfPLgltpvq ILsIDLisDipPavSLAYEg pEaDIMlqp.PRk.kdth.. .................... .................... ...................L VtkgLitytYlfmsifisig cvcaYllsyyinG....... .igPweLaftastyfkhgaa nfttakGvilneeqqmyman qaaaaFhislvlgQafhLwm clTRRvSiFahG.lgNivai faviidllliciftfvPGvk yifgsqpp.pwqcWlvpivv gvwIwifnElRklgiRkyPk n.kfvrltkw.......... 
   -   O16331    Caenorhabditis elegans     C09H5.2          ...............mgfll gvvrslrqrreaadsenssf keathkdlsssfvehqmhia qlserffhskidivepkksk GLtkqeAaqkLktDGkNaLs PPktisnmelFvrqfknllw vLmfgaAalCfltyiydptd a.......lNLYvgifivai VfimcvvsffeEkKgvevvr aFqtlmPtscqViRdGkeil lnpeelVvGDvVvvrsGckv PADmRiiactdffletSSiT GEaEPlefhsktadaktsif EsyNiaFngsfcvdGegyGi iirtGenTviGqIAsLtlGq kdkkckfetEIerFvqfItv mAitmatviFtigllvnggn dvirlfvtgflmviiAnVPq GLptTVTteLtiiArRmAkK NvflKkLEkidsvGaTtlIa SDKTGTLTkNcMTVtdlWyn nsynsArpenqgrttkkrnl naintigwydaplkdilsvi cvCNkAriennlttkvrppr vdseldltvyksqPvkemli sGnpSEvALLryasgmlda. ..mevRdsfhvvfEvPFNSv rKyhlilatteatwaeiddk kkvnadvefilmiKGAPdvl iksCStIni.dGvpmeLngk rmddFneAYetfGdeGcRVi GFackkfrap...atstFsi ksn.tiPmdnwdFlGmsaim DPPRddtPrAikaCkeAGIk VyMVTGDHksTAtAIArqiG mId..tEeVtnldhnrqvir rtnsq........d.waVit GpeLpglsekqwdalLe.hr yIVFARTtPehKLmIVtesQ krGecVtVTGDGVNDaPALK KADvGvAMGlaGSDvaKqAA DiILLDDNFsSIVaGiEEGR LlFDNLrKtIAYTmThmwPE lvPvmlnfffgfPLgltpvq ILsIDLiTDipPavSLAYEg pEaDIMlqp.PRk.reth.. .................... .................... ...................L VtkgLitytYlfmsifisvg GvvaYllsyylnG....... .iyPseLafssndhfkvgas nfttynGvvlnaeqqvfmaa qaaaaFhiavvvgQawhLwm clTRRvSiFvhG.maNivai laviidllliclftfvPGvq yvfgsqpp.pwecWlvpviv giwIwifnElRkfgiRnyPk n.klvrlvkw.......... 
   -   O43134    Blastocladiella emersonii  PAT1             .................... ...................m akdkqkkatslaldehrltl devcaryktgadavhpahst GLtpdeAarrLaaDGPNlma PPktkhpllrylecllalfn fLllvaAaftyllygldpvs n......yaNiYtgsiLvaV aflnafieYYQvaKSeaalr aFldmiPakAtavRgGqlvv vpAsdlVkGDvVfvrmGDkm PADvflfktadmKVDNaSLT GESEPQdRspvnTheaa..L EatNlaFnSTlvvaGegyGi VvrtGDdTviGqIAnmtqte tkrmsPlteEIeaFvkfIgs lAvlcaiiFFiiaqlkt... ndigisfnFavgvlVAwVPE GLpgTVTmlLtiaAKRmAgq qvlVKdLtgVETLGaitlla tDKTGTLTrNqMTVsnvWth fktfalvadvrslq...... dgevafdssvkgvqdvmnis aLCsRArFd........... .........ktnvPmdqrei iGDAtEtgLyrlatqkird. .fdqladkypKvlEIPFNSd tKwhmSIHkmaha....... .....ngsfttfiKGAPERv LriCStIlddnGdtipLtde hkiqFntAYeymaskGhRVL aFakfeLpgteyPeshvFdk elk.NFPmagLtFvGLaSle DPPkhgVreAVgnCRrAGIk VvMVTGDHPlTAeAIgrkin lmis..dTkEkvAkkagipv adVre......edvkAiVih Gekidslteedwdiifs.kd EIiFARTSPkhKLqIVkraQ amGhiVgVTGDGVNDSPALK KADlGiAMnIsGSDvsKeAA aMILLDDNFASIinGirEGR LIFfNLKKSsAtwsrdsIPE vlPqLlyvvvplPvglnalq IiaIDLgfelfaalSyAYEp pEsDtlmklqPRrpvdtesi ehlrarrefdnrfkslpana devdendflrqltfgerikr mfsgeywskwafatadgemL VdwntlswsYleaGiiQylg ahvafFvvfymykdkdgksl yitPtdLytcasnegwtgkk DctlgsGlplsiddqkesla qaqsvwFfgIflmQawnLfa cKclmtSpFtthifkNkstl lsllggliltviitYvPGin tafgcsynlnplyllipfgv gfvlflYaglRhwikmrfsp hqvqpeplglqmhptrwsaa 
   -   O76154    Dugesia japonica                            .................... masdekvndkgdlknlkgsp kkskkdkkkdldnlKkEldi dsHripikdlyirlqsdpdk GisyedAkmrLarDGPNaLt PPktTPEwvKFckqlfGGfs lLlWigAvlCflAyaIqsga yedppk..DNLYLgvvLtaV VviTGcFsYYQdaKSskIme SFgkmvPQkAnViReGkise isAenlVvGDviEvKfGDrv PADiRviqassfKVDNSaLT GESEaQvRtpefTndnP..L ETkNiaFfSTnavEGTcrGi VisvGDnTvmGRIAnLASGl emgmTPIAkEInHFihiItG vAvflGvsFFviafilg... YfwLdAviFligIiVAnVPE GLLATVTVcLtLTAKRmAkK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nkIqesDTsEn......... qitssskqeSdtwkmLaris mLCNRAqFk........... .......ageedkPvlKrdc tGDASEsALLKcvElsiGg. .vtkyReenkKivEIPFNST NKyQvSIHetndg....... .....npgyliaMKGAPERi LerCStIli.dGkEvhmDdh wkqeFnnAYleLGGmGERVL GFCdfrLdenefPkgfkFnp dev.NFPldgLrFvGLmSMI DPPRaaVPDAVaKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnrTVdDIAaergisp seVNp......rdArAcVih GsdLrdmtseqldevLkhhd EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR iIFDNLKKSIAYTLTsNIPE itPfLvfIladvPLPlGtiT ILcIDLgTDmvPaiSLAYEe aEsDIMkrk.PRdpkhDk.. .................... .................... ...................L VNerLismaYgQIGmiQasg GFfvYFvimAeqG....... .fwPsrLlglRkeWdsaavn DlaDSYGQeWTfeqRkkley TchTaFFvsIvivQwtDLmI cKTRRnSiFqQG.mwNhqmt fglffettlaafLtYcPGld valkmqpl.rftwWlpaiPf sasIfiYDEvRkyllRkwkn gsWlenetYY.......... 
   98  O45240    Caenorhabditis elegans     C01G12.8         ...mcqppppplrpfsqktk iinnqsviasirkssfimfg cfkkkktnksledlKkdvvi ddHeipldalfkryttsekn GiseaeAtnrLnrDGPNaLt PPkqTskwiKlagsifGGfn fLlWcaAsasavgygmdlsm sddeevpkDNmYmaiiLatV VtvTGlFdfYQnrKSgnlmd SFanmiPpktlVvRdGatre ievkdlVvGDlVrfrgGDrv PADlRvtlarglKVDNSSLT GESEPQtRnmncTskna..L ETkNlcmfSTsvlEGsgeGi iigtGDrTfvGRIAaLttqv dpgpTPlAkEInHFikiIsi vAftvGiaFFilalvye... YppLkAivFfmgIvVAnVPE GivpTVTVsLtLTAvkmrkK fClVKkLqAVETLGSTStIC SDKTGTLTQNRMTVtHlWFD gkIkdteilpp......ndh fkgekkyekedsyqkLlrca tLCsRshFr........... .......vpefdvPlaKrvv nGDASEvAimrycEmirGdg qvdefRkimpKigEIPFNST NKyQlSIHpmskk....... .......qnilVMKGAPEki LklCStyyq.nGetknvskk fekeFqqAYetLGsyGERVL GFCdlemsttkfPpgfkFnm eep.NFPiknLrFlGLiSMI DPPRpgVPeAVrvCqnAGIr VvMVTGDHPITArAIAnqVh IIeenvqvtEivnadpkcdp asdeiygkgrlkptgAvVih GeqLttmspktlkavvtnyh qIVFARTSPaQKLqIVEafQ svGniVgVTGDGVNDaPALr KADIGiAMGItGtDvsKqAA DMILLnDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfmsyvlfglPLPmsiia ILmIDLgTDlwPaiSfAYEv pEsDIMqra.PRnplyDk.. .................... .................... ...................L VNkrLvmfsYmQIGaiQaca GFttYFvlmmsnG....... .wfPqdLlniseqWdnkyid DleDSYGQqWsyesRkales ccygtFFftIvvtQwsDLfa sKTRknSlvmQG.meNhvln tsviftcflaifvlntPfvn evlgvqgf.rleigflalPf affIglYDEvRryfiRtyPG g.yiyketYY.......... 
   99  P35317    Hydra vulgaris                              .............madpgdl esrgkadsysvaekksapkk iskknankakledlKkElem teHsmklesllsmyetslek GLsenivarnLerDGlNaLt PPkqTPEwvKFckqmfGGfs mLlWigAilCffAfgIravr d.tnpnm.DeLYLgivLsvV ViiTGcFsYYQEsKSskIme SFkkmiPQeAlVlRdGkKit inAeqcVvGDvVfvKfGDri PADiRiveckglKVDNSSLT GESEPQsRavdfThenP..i ETkNlaFfSTnavEGTatGi VvriGDnTvmGRIAnLASGl gsgkTPIAlEIeHFihivtG vAvflGvsFliislamg... YhwLeAiiFligIiVAnVPE GLLATVTVcLtLTAKkmAkK NClVKhLEAVETLGSTSvIC SDKTGTLTQNRMTVaHmWFD kmIveADTtEd......... qsgiahdkgSltwksLakva aLCsRAeFk........... .......pnqndvavlrkec tGDASEtAiLKfvElsvGn. .vmdiRaknkKvtEIPFNST NKyQvSvHeqens....... ....sg..yllVMKGAPEkv LerCStIli.nGeEqpLkdd vieiynkAYdeLGGlGERVL GFChyyLpvdqyPkgflFkt eeeqNFPlegLcFlGLlSMI DPPRaaVPDAVsKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnEceEDIAlRlnipl edlsedqk...ksAkAcVih GakLkdikneeldkiLcdht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIvYTLTsNIPE isPfLmfIlfgiPLPlGtiT ILcIDLgTDmvPaiSLAYEk aEsDIMkrh.PRnpirDk.. .................... .................... ...................L VNerLislaYgQIGmmQata GFftYFiilAenG....... .flPsyLfglRsqWddmsnn nllDSfGseWTyfqRkeiel TcqTaFFttIvvvQwaDLiI sKTRRlSlFqQG.mtNwfln fglffetalaafLqYtPGvn tglrlrpm.nftwWlpglPf sllIfvYDEiRryllRknPG g.WveketYY.......... 
  100  P28774    Artemia franciscana                         .................... ...................m akgkqkkgkdlnelKkEldi dfHkipieEcyqrlgsnpet GLtnaqArsnierDGPNcLt PPktTPEwiKFcknlfGGfa lLlWtgAilCflAygIeass gnedmlk.DNLYLgivLatV VivTGiFsYYQEnKSsrImd SFknlvPQyAlalReGqrvt lkAeeltmGDiVEvKfGDrv PADlRvlearsfKVDNSSLT GESEPQaRspefTndnP..L ETkNlaFfSTnavEGTmrGi VigiGDnTvmGRIAgLASGl dtgeTPIAkEIaHFihiItG vAvflGvtFFiiafvlg... YhwLdAvvFligIiVAnVPE GLLATVTVcLtLTAKRmAsK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD gtIteADTtEd......... qsgaqfdksSagwkaLvkia aLCsRAeFk........... .......pnqsttPilKrev tGDASEaAiLKcvElttGe. .teaiRkrnkKicEIPFNSa NKfQvSIHenedk....... ....sdgryllVMKGAPERi LerCStIfm.nGkEidmtee lkeaFnnAYmeLGGlGERVL GFCdylLpldkyPhgfaFna dda.NFPltgLrFaGLmSMI DPPRaaVPDAVaKCRsAGIk VIMVTGDHPITAKAIAksVG IISegnETVEDIAaRlnipv seVNp......rdAkAaVvh GgeLrditpdaldeiLrhhp EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIvYTLTsNIPE isPfLlfIlfdiPLPlGtvT ILcIDLgTDmvPaiSLAYEe aEsDIMkrr.PRnpvtDk.. .................... .................... ...................L VNerLislaYgQIGmiQasa GFfvYFvimAecG....... .flPwdLfglRkhWdsravn DltDSYGQeWTydaRkqles schTayFvsIvivQwaDLiI sKTRRnSvFqQG.mrNniln falvfetclaafLsYtPGmd kglrmypl.kinwWfpalPf sflIfvYDEaRkfilRrnPG g.WveqetYY.......... 
  101  Q27461    Caenorhabditis elegans     eat-6 / B0365.3  .................... .................... .mgkkdkkqelhdlKqEvkm deHivpieElvarlgtnlet GLtrqkAqevLaknGPNaLs PPetTPEwiKFcknlfGGfa mLlWvgAilCyiAysvdyft m.eypsk.DNLYLgivLmtV VviTGvFqYYQEsKSskImd SFknmvPtfAlVhRdGqKqq vkteelVvGDiVEvKgGDrv PADlRvvsafgfKVDNSSLT GESEPQsRspdcTnenP..L ETrNiaFfSTnavEGTakGi ViytGDnTvmGRIAhLASGl dtgmTPIArEIeHFihlItG vAvflGisFFiiafilg... YhwLtAvvFligIiVAnVPE GLiATVTVcLtLTAKRmAsK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWyD etIhecDTtEt......... qts.qekrtgasfeaLvria sLCNRAeFk........... .......agqqdtPilrrdc tGDASEiALLKftEltqGn. .viavReknkKiaEIPFNST NKyQvSIHdngd........ .......hyllVMKGAPERi LdvCStIfl.nGkEseLtdk lredFntAYleLGGmGERVL GFCdfvLpadkfPkgfkFdv eev.NFPlknLrFvGLmSMI DPPRaaVPDAVaKCRsAGIk VvMVTGDHPITAKAIAksVG IISdgtETVEDIAiRrgipv eeVNp......reAkAaVih GsdLremsedqlaeiikyhs EIVFARTSPQQKLmIVEgfQ kqGqiVAVTGDGcNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASyVvGVEEGR LIFDNLKKSIAYTLTsNIPE isPfLtyIlfgiPLPlGtvT ILcIDLgTDmvPaiSLAYEe aEsDIMkrq.PRdpirDk.. .................... .................... ...................L VNerLislaYgQIGmiQasa GFftYFwimAdnG....... .fmPwdLyqlRaqWdsrayn nvlDSYGQeWTyanRkiley TcqTayFvsIvvvQwaDLiI sKTRRnSlvqQG.msNwtln fglvfetalawfmcYcPGld nglrmygl.rfswWfcalPf silIfvYDEiRrfliRryPG g.WveretYY.......... 
  102  P13607    Drosophila melanogaster    NA-P             .malrsdyehgradsyrvat viatdddnrtadgqyksrrk mpakvnkkenlddlKqEldi dfHkispeEmyqrfqthpen GLsharAkenLerDGP.nLt PPkqTPEwvKFcedlfG.va mLlWigAilCfvAysIqast s.eepad.DNLYLgivLsaV VivTGvFsYYQEsKSskIme SFknmvPQfAtViReGeKps lrAedlVlGvlVElefGDli PlvyRiieardfKVDNSSLT GESEPQsRgaefThenP..L ETkNlaFfSTnavEalpkGv ViscGDhTvmGRIAaLASGl dt.gTPIAkEIhHFihlItG vAvflGvtFFviafilg... YhwLdAviFligIiVAnVPE GLLATVTVcLtLTAKRmAsK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIieADTtEd......... qsgvqydrtSpgfkaLsria tLCNRAeFk........... .......ggqdgvPilKkev sGDASEaALLKcmElalGd. .vmniRkrnkKiaEvPFNST NKyQvSIHetedt....... ....ndpryllVMKGAPERi LerCStIfi.nGkEkvLDee mkeaFnnAYmeLGGlGERVL GFCdfmLpsdkyPngfkFnt ddi.NFPidnLrFvGLmSMI DPPRaaVPDAVaKCRsAGIk VIMVTGDHPITAKAIAksVG IISegnETVEDIAqRlnipv seVNp......reAkAaVvh GaeLrdvssdqldeiLryht EIVFARTSPQQKLiIVEgCQ RmGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE isPfLasIlcdiPLPlGtvT ILcIDLgTDmvPaiSLAYdh aEaDIMkrp.PRdpfnDk.. .................... .................... ...................L VNsrLismaYgQIGmiQaaa GFfvYFvimAenG....... .flPkkLfgiRkmWdskavn DltDSYGQeWTyrdRktley TchTaFFisIvvvQwaDLiI cKTRRnSiFqQG.mrNwaln fglvfetvlaafLsYcPGme kglrmypl.klvwWfpaiPf alaIfiYDEtRrfylRrnPG g.WleqetYY..........
  103  Q27766    Ctenocephalides felis                       .....mddkhgrsdsyrvat vptiddnltadgqyksrrkt ptkkqrkegelddlKqEldi dfHkvspeElyqrfnthpen GLshakAkenLerDGPNaLt PPkqTPEwvKFcknlfGGfa lLlWigAilCfvAysIqast v.eepad.DNLYLgivLaaV VivTGiFsYYQEsKSskIme SFknmvPQfAtVlReGeKlt lrAedlVlGDvVEvKfGsri PADiRiiesrgfKVDkSSLT GESEPQsRgpefTnekP..L ETkNlaFfSinavEGTakGv ViscGDnTvmGRIAgLASGl dtgeTPIAkEIhHFihlItG vAvflGvtFFviaiiln... YhwLdAviFligIiVAnVPE GLLATVTVcLtLTAKRmAsK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIieADTtEd......... qsgvvydrtSpgfkaLaria tLCNRAeFk........... .......ggqegvPilKkev sGDASEaALLKcmElalGd. .vmsiRkrnkKvcEIPFNST NKyQvSIHeteda....... ....sdprhvmVMKGAPERi LekCStIfi.gGkEklLDee mkeaFnnAYleLGGlGERVL GFCdlmLptdkfPlgfkFds ddp.NFPienLrFvGLmSMI DPPRaaVPDAVaKCRsAGIk VIMVTGDHPITAKAIAksVG IISegnETVEDIAqRlnipv seVNp......reAkAaVvh GteLrelnsdqldeiLryht EIVFARTSPQQKLiIVEgCQ RmGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE isPfLafIlcdiPLPlGtvT ILcIDLgTDmvPaiSLAYEh aEaDIMkrp.PRdpvnDk.. .................... .................... ...................L VNsrLismaYgQIGmiQaaa GFfvYFvimAenG....... .flPmkLfgiRkqWdskavn DltDSYGQeWTyrdRktley TchTaFFvsIvvvQwaDLiv cKTRRnSllhQG.mrNwaln fglvfetalaafLsYtPGmd kglrmfpl.kfvwWlpalPf misIfiYDEtRrfylRrnPG g.WleqetYY.......... 
  104  P05023    Homo sapiens               ATP1A1 / NaKa1   ...................m gkgvgrdkyepaavseqgdk kgkkgkkdrdmdelKkEvsm ddHklsldElhrkygtdlsr GLtsarAaeiLarDGPNaLt PPptTPEwiKFcrqlfGGfs mLlWigAilCflAysIqaat eeepqn..DNLYLgvvLsaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlViRnGeKms inAeevVvGDlVEvKgGDri PADlRiisangcKVDNSSLT GESEPQtRspdfTnenP..L ETrNiaFfSTncvEGTarGi VvytGDrTvmGRIAtLASGl eggqTPIAaEIeHFihiItG vAvflGvsFFilslile... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgvsfdktSatwlaLsria gLCNRAvFq........... .......anqenlPilKrav aGDASEsALLKciElccGs. .vkemReryaKivEIPFNST NKyQlSIHknpnt....... ....sepqhllVMKGAPERi LdrCSsIll.hGkEqpLDee lkdaFqnAYleLGGlGERVL GFChlfLpdeqfPegfqFdt ddv.NFPidnLcFvGLiSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv sqVNp......rdAkAcVvh GsdLkdmtseqlddiLkyht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLifIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEq aEsDIMkrq.PRnpktDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvilAenG....... .flPihLlglRvdWddrwin DveDSYGQqWTyeqRkivef TchTaFFvsIvvvQwaDLvI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmg valrmypl.kptwWfcafPy sllIfvYDEvRkliiRrrPG g.WveketYY.......... 
 (104) P30714    Bufo marinus               ATP1A1 / NaKa1   .................mgy gagrdkyepaatsehgg..k kgkgkgkdrdmeelKkEvtm edHkmtleElhrkygtdltr GLttarAaeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs mLlWigAilCflAygIrkas dlepdn..DNLYLgvvLsaV ViiTGcFsYYQEaKSsrIme SFknmvPQqAlViRnGeKls inAenvVqGDlVEvKgGDri PADlRiisahgcKVDNSSLT GESEPQtRspdfTnenP..L ETrNiaFfSTncvEGTarGi VintGDrTvmGRIAtLASGl eggqTPIAvEIgHFihiItG vAvflGvsFFilslilh... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgasfdksSptwtaLaria gLCNRAvFp........... .......agqentPilKrdv vGDASEsALLKciElccGs. .vkdmReknqKvaEIPFNST NKyQlSvHknanp....... ....sesryllVMKGAPERi LdrCSsIll.qGkEqpLDee lkdaFqnAYleLGGlGERVL GFChllLddeqfPdgfsFdt edv.NFPtegLcFvGLiSMI DPPRaaVPDrVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv nqVNp......rdAkAcVih GtdLkdmnadqiddiLrhht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGiAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLifIiadiPLPlGtvT ILcIDLgTDmvPaiSLAYEq aEsDIMkrh.aRnpkkDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFfaYFvilAenG....... .flPstLlgiRvaWedryvn DveDSYGQqWTyeqRkivef TchTaFFvsIvvvQwaDLiI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmd valrmypl.kptwWfcafPy sllIfiYDEvRklilRrsPG g.WveketYY.......... 
 (104) P50997    Canis familiaris           ATP1A1 / NaKa1   ...................m gkgvgrdkyepaavsehgdk ..kkakkerdmdelKkEvsm ddHklsldElhrkygtdlsr GLttarAaeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs mLlWigAilCflAygIqaat eeepqn..DNLYLgvvLsaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlViRnGeKms inAeevViGDlVEvKgGDri PADlRiisangcKVDNSSLT GESEPQtRspdfTnenP..L ETrNiaFfSTncvkGTarGi VvytGDrTvmGRIAtLASGl eggqTPIAaEIeHFihiItG vAvflGvsFFilslile... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgvsfdksSatwlaLsria gLCNRAvFq........... .......anqenlPilKrav aGDASEsALLKciElccGs. .vkemRdryaKivEIPFNST NKyQlSIHknpnt....... ....seprhllVMKGAPERi LdrCSsIll.hGkEqpLDee lkdalqnAYleLGGlGERVL GFrhlfLpdeqfPegfqFdt ddv.NFPvenLcFvGfiSMI gPPRaaVPDAVgKCRgAGIk VIMVTGDHPITAKAIAkgaG IISegnETVEDIAaRlnipv rqVNp......rdAkAcVvh GsdLkdmtseqldgiLkyht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIvGSDasKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLifIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEq aEsDIMkrq.PRnpktDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvilAenG....... .flPthLlglRvdWddrwin DveDSYGQqWTyeqRkivef TchTaFFvsIvvvQwaDLvI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmg valrmypl.kptwWfcafPy sllIfvYDEvRkliiRrrPG g.WveketYY.......... 
 (104) P18907    Equus caballus             ATP1A1 / NaKa1   ...................m gkgggrdkyepaaisehgnk ..kkakkerdmdelKkEvsm ddHklsldElqrkygtdlsr GLttarAaeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs mLlWigAilCflAygIqaat eeepqn..DNLYLgvvLsaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlVvRnGeKms inAeevVvGDlVEvKgGDri PADlRiisangcKVDNSSLT GESEPQtRspdfTnenP..L ETrNiaFfSTncvEGTarGi VvytGDrTvmGRIAtLASGl eggqTPIAaEIeHFihiItG vAvflGvtFFilslile... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgvsfdktSatwlsLsria gLCNRAvFq........... .......anqeniPilKrav aGDASEsALLKciElccGs. .vkemRdrypKivEIPFNST NKyQlSIHknpnt....... ....sepqhllVMKGAPERi LdrCSsIll.nGkEqpLDee lkdaFqnAYleLGGlGERVL GFChlfLpdeqfPegfqFdt ddv.NFPlenLcFvGLiSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv sqVNp......rdAkAcVvh GsdLkdmtpeqlddiLrhht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLifIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEq aEsDIMkrq.PRnpqtDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvilAenG....... .flPihLlglRvdWddrwvn DveDSYGQqWTyeqRkivef TchTaFFvsIvvvQwaDLvI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmg valrmypl.kptwWfcafPy sllIfvYDEvRkliiRrrPG g.WveketYY.......... 
 (104) P09572    Gallus gallus              ATP1A1 / NaKa1   ...................m gkgagrdkyeptatsehgtk ..kkkakerdmdelKkEism ddHklsldElhrkygtdlsr GLttarAaeiLarDGPNtLt PPptTPEwvKFcrqlfGGfs lLlWigsllCflAygItsvm egepns..DNLYLgvvLaaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlVvRnGeKms inAegvVvGDlVEvKgGDri PADlRiisahgcKVDNSSLT GESEPQtRspdfsnenP..L ETrNiaFfSTncvEGTavGi VistGDrTvmGRIAsLASGl eggkTPIAmEIeHFihlItG vAvflGvsFFilslile... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVgTLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgasfdksSatwlaLsria gLCNRAvFq........... .......anqenvPilKrav aGDASEsALLKciElccGs. .vkemRerypKvvEIPFNST NKyQlSIHknana....... ....gesrhllVMKGAPERi LdrCdsIli.hGkvqpLDee ikdaFqnAYleLGGlGERVL GFChlaLpddqfPegfqFdt dev.NFPvekLcFvGLmSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISdgnETVEDIAaRlnipv sqVNp......rdAkAcVvh GsdLkdmtseqlddiLlhht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLifIianiPLPlGtcT ILcIDLgTDmvPaiSLAYEq aEsDIMkrq.PRnpktDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvimAenG....... .flPsgLvgiRlqWddrwin DveDSYGQqWTfeqRkivef TchTaFFvsIvvvQwaDLiI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmd valrmypl.kptwWfcafPy sllIflYDEiRkliiRrnPG g.WveretYY.......... 
 (104) P04074    Ovis aries                 ATP1A1 / NaKa1   ...................m gkgvgrdkyepaavsehgdk ..kkakkerdmdelKkEvsm ddHklsldElhrkygtdlnr GLttarAaeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs mLlWigAvlCflAygIqaat eeepqn..DNLYLgvvLsaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlViRnGeKms inAeevVvGDlVEvKgGDri PADlRiisangcKVDNSSLT GESEPQtRspdfTnenP..L ETrNiaFfSTncvEGTarGi VvytGDrTvmGRIAtLASGl eggqTPIAaEIeHFihiItG vAvflGvsFFilslile... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgvsfdktSatwlaLsria gLCNRAvFq........... .......anqdnlPilKrav aGDASEsALLKciEvccGs. .vkemReryaKivEIPFNST NKyQlSIHknana....... ....geprhllVMKGAPERi LdrCSsIli.hGkEqpLDee lkdaFqnAYleLGGlGERVL GFChlmLpdeqfPegfqFdt ddv.NFPvdnLcFvGLiSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv sqVNp......rdArAcVvh GsdLkdmtpeqlddiLkyht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLifIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEq aEsDIMkrq.PRnpqtDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvimAenG....... .flPnhLlgiRvtWddrwin DveDSYGQqWTyeqRkivef TchTaFFvsIvvvQwaDLvI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmg valrmypl.kptwWfcafPy sllIfvYDEvRkliiRrrPG g.WveketYY.......... 
 (104) P06685    Rattus norvegicus          ATP1A1 / NaKa1   ...................m gkgvgrdkyepaavsehgdk kskkakkerdmdelKkEvsm ddHklsldElhrkygtdlsr GLtparAaeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs mLlWigAilCflAygIrsat eeeppn..DdLYLgvvLsaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlViRnGeKms inAedvVvGDlVEvKgGDri PADlRiisangcKVDNSSLT GESEPQtRspdfTnenP..L ETrNiaFfSTncvEGTarGi VvytGDrTvmGRIAtLASGl eggqTPIAeEIeHFihlItG vAvflGvsFFilslile... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgvsfdktSatwfaLsria gLCNRAvFq........... .......anqenlPilKrav aGDASEsALLKciEvccGs. .vmemRekytKivEIPFNST NKyQlSIHknpna....... ....sepkhllVMKGAPERi LdrCSsIll.hGkEqpLDee lkdaFqnAYleLGGlGERVL GFChllLpdeqfPegfqFdt dev.NFPvdnLcFvGLiSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv nqVNp......rdAkAcVvh GsdLkdmtseelddiLryht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIvGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLifIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEq aEsDIMkrq.PRnpktDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvilAenG....... .flPfhLlgiRetWddrwin DveDSYGQqWTyeqRkivef TchTaFFvsIvvvQwaDLvI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmg aalrmypl.kptwWfcafPy sllIfvYDEvRkliiRrrPG g.WveketYY.......... 
 (104) P05024    Sus scrofa                 ATP1A1 / NaKa1   ...................m gkgvgrdkyepaavsehgdk ..kkakkerdmdelKkEvsm ddHklsldElhrkygtdlsr GLtparAaeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs mLlWigAilCflAygIqaat eeepqn..DNLYLgvvLsaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlViRnGeKms inAeevVvGDlVEvKgGDri PADlRiisangcKVDNSSLT GESEPQtRspdfTnenP..L ETrNiaFfSTncvEGTarGi VvytGDrTvmGRIAtLASGl eggqTPIAaEIeHFihiItG vAvflGvsFFilslile... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWsD nqIheADTtEn......... qsgvsfdktSatwlaLsria gLCNRAvFq........... .......anqenlPilKrav aGDASEsALLKciElccGs. .vkemRerytKivEIPFNST NKyQlSIHknpnt....... ....aeprhllVMKGAPERi LdrCSsIli.hGkEqpLDee lkdaFqnAYleLGGlGERVL GFChlfLpdeqfPegfqFdt ddv.NFPldnLcFvGLiSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv sqVNp......rdAkAcVvh GsdLkdmtseqlddiLkyht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPAsK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLifIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEq aEsDIMkrq.PRnpktDk.. .................... .................... ...................L VNeqLismaYgQIGmiQalg GFftYFvilAenG....... .flPihLlglRvnWddrwin DveDSYGQqWTyeqRkivef TchTpFFvtIvvvQwaDLvI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmg valrmypl.kptwWfcafPy sllIfvYDEvRkliiRrrPG g.WveketYY.......... 
 (104) Q92123    Xenopus laevis             ATP1A1 / NaKa1   .................mgy gagrdkyepaatseqggkkk kgkgkgkekdmdelKkEvtm edHklsldElhrkfgtdmqr GLttarAaeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs mLlWigAilCflAygIqaam eeepqn..DNLYLgvvLsaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlViRsGeKls inAeevVlGDlVEvKgGDri PADlRvisshgcKVDNSSLT GESEPQtRspdfTnenP..L ETrNiaFfSTncvEGTarGi VvntGDrTvmGRIAtLASGl dggrTPIAiEIeHFihiItG vAvflGvsFFilslilq... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgasfdksSptwtaLsrva gLCNRAvFq........... .......agqentPilKrdv aGDASEsALLKciElccGs. .vrdmReknhKvaEIPFNST NKyQlSvHknanp....... ....sesryilVMKGAPERi LdrCtsIil.qGkEqpLDee lkdaFqnAYleLGGlGERVL GFChlaLpddqfPdgfqFdt eev.NFPtenLcFvGLiSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv nqVNp......rdAkAcVih GtdLkdmteeqiddiLrhht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGiAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLifIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEq aEsDIMkrq.PRnpktDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvilAenG....... .flPwtLlgiRvnWddrwtn DveDSYGQqWTyeqRkivef TchTsFFisIvvvQwaDLiI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmd valrmypl.kptwWfcafPy sliIfiYDEvRkliiRrsPG g.WvekesYY.......... 
  105  P05025    Torpedo californica        ATP1A1 / NaKa1   ...................m gkgaasekyqpaatsenakn skkskskttdldelKkEvsl ddHklnldElhqkygtdltq GLtparAkeiLarDGPNaLt PPptTPEwiKFcrqlfGGfs iLlWtgAilCflAygIqvat vdnpan..DNLYLgvvLstV ViiTGcFsYYQEaKSskImd SFknmvPQqAlViRdGeKss inAeqvVvGDlVEvKgGDri PADlRiisacscKVDNSSLT GESEPQsRspeyssenP..L ETkNiaFfSTncvEGTarGi ViniGDhTvmGRIAtLASGl evgqTPIAaEIeHFihiItG vAvflGvsFFilslilg... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgisfdktSlswnaLsria aLCNRAvFq........... .......agqdsvPilKrsv aGDASEsALLKciElccGs. .vsqmRdrnpKivEIPFNST NKyQlSIHendka....... .....dsryllVMKGAPERi LdrCStIll.nGedkpLnee mkeaFqnAYleLGGlGERVL GFChlkLstskfPegypFdv eep.NFPitdLcFvGLmSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv nqVNp......rdAkAcVvh GtdLkdlshenlddiLhyht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLvfIianvPLPlGtvT ILcIDLgTDmvPaiSLAYEr aEsDIMkrq.PRnpktDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFfsYFvilAenG....... .flPidLigiRekWdelwtq DleDSYGQqWTyeqRkivey TchTsFFvsIvivQwaDLiI cKTRRnSiFqQG.mkNkili fglfeetalaafLsYtPGtd ialrmypl.kpswWfcafPy sliIflYDEaRrfilRrnPG g.WveqetYY.......... 
  106  P13637    Homo sapiens               ATP1A3 / NaKa3   .................... .........mgdkkddkdsp kknkgkerrdlddlKkEvam teHkmsveEvcrkyntdcvq GLthskAqeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs iLlWigAilCflAygIqagt eddpsg..DNLYLgivLaaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlViReGeKmq vnAeevVvGDlVEiKgGDrv PADlRiisahgcKVDNSSLT GESEPQtRspdcThdnP..L ETrNitFfSTncvEGTarGv VvatGDrTvmGRIAtLASGl evgkTPIAiEIeHFiqlItG vAvflGvsFFilslilg... YtwLeAviFligIiVAnVPE GLLATVTVcLtvTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEd......... qsgtsfdksShtwvaLshia gLCNRAvFk........... .......ggqdniPvlKrdv aGDASEsALLKciElssGs. .vklmRernkKvaEIPFNST NKyQlSIHetedp....... ....ndnryllVMKGAPERi LdrCStIll.qGkEqpLDee mkeaFqnAYleLGGlGERVL GFChyyLpeeqyPqgfaFdc ddv.NFttdnLcFvGLmSMI gPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv sqVNp......rdAkAcVih GtdLkdftseqideiLqnht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLlfImaniPLPlGtiT ILcIDLgTDmvPaiSLAYEa aEsDIMkrq.PRnprtDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFfsYFvilAenG....... .flPgnLvgiRlnWddrtvn DleDSYGQqWTyeqRkvvef TchTaFFvsIvvvQwaDLiI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmd valrmypl.kpswWfcafPy sflIfvYDEiRklilRrnPG g.WveketYY.......... 
 (106) P24798    Gallus gallus              ATP1A3 / NaKa3   .................... ............mgdkgeke spkkgkgkrdlddlKkEvam teHkmsieEvcrkyntdcvq GLthskAqeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs iLlWigAilCflAygIqagt edepsn..DNLYLgivLaaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlViReGeKmq lnAeevVvGDlVEvKgGDrv PADlRiisahgcKVDNSSLT GESEPQtRspdcThdnP..L ETrNitFfSTncvEGTarGv ViatGDrTvmGRIAtLASGl evgkTPIAvEIeHFiqlItG vAvflGisFFvlslilg... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEd......... qsgtsfdksSatwvaLshia gLCNRAvFk........... .......ggqenvPilKrdv aGDASEsALLKciElssGs. .vkvmRernkKvaEIPFNST NKyQlSIHetedp....... ....ndnryllVMKGAPERi LdrCStIll.qGkEqpLDee mkeaFqnAYleLGGlGERVL GFChfyLpeeqyPkgfaFdc ddv.NFatdnLcFvGLmSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv sqVNp......rdAkAcVih GtdLkdmsseqideiLqnht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIrGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLlfImaniPLPlGtiT ILcIDLgTDmvPaiSLAYEa aEsDIMkrq.PRnprsDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFfsYFvilAenG....... .flPscLvgiRlsWddrtin DleDSYGQqWTyeqRkvvef TchTaFFvsIvvvQwaDLiI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmd valrmypl.kpswWfcafPy sflIfvYDEiRklilRrnPG g.WveketYY.......... 
 (106) P06687    Rattus norvegicus          ATP1A3 / NaKa3   .................... .........mgdkkddkssp kkskakerrdlddlKkEvam teHkmsveEvcrkyntdcvq GLthskAqeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs iLlWigAilCflAygIqagt eddpsg..DNLYLgivLaaV ViiTGcFsYYQEaKSskIme SFknmvPQqAlViReGeKmq vnAeevVvGDlVEiKgGDrv PADlRiisahgcKVDNSSLT GESEPQtRspdcThdnP..L ETrNitFfSTncvEGTarGv VvatGDrTvmGRIAtLASGl evgkTPIAiEIeHFiqlItG vAvflGvsFFilslilg... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEd......... qsgtsfdksShtwvaLshia gLCNRAvFk........... .......ggqdniPvlKrdv aGDASEsALLKciElssGs. .vklmRernkKvaEIPFNST NKyQlSIHetedp....... ....ndnryllVMKGAPERi LdrCatIll.qGkEqpLDee mkeaFqnAYleLGGlGERVL GFChyyLpeeqfPkgfaFdc ddv.NFttdnLcFvGLmSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv sqVNp......rdAkAcVih GtdLkdftseqideiLqnht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLlfImaniPLPlGtiT ILcIDLgTDmvPaiSLAYEa aEsDIMkrq.PRnprtDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFfsYFvilAenG....... .flPgnLvgiRlnWddrtvn DleDSYGQqWTyeqRkvvef TfhTaFFvsIvvvQwaDLiI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmd valrmypl.kpswWfcafPy sflIfvYDEiRklilRrnPG g.WveketYY.......... 
  107  Q92030    Anguilla anguilla                           .................... mgrgtghdqyelaatseggr kkkrdkkkkdmddlKkEvdl ddHkltldElhrkygtdltr GLtssrAaeiLarDGPNaLt PPptTPEwvKFcrqlfGGfs mLlWigAilCflAygIqaas edepan..DNLYLgvvLsaV ViiTGcFsYYQEaKSsrImd SFknlvPQqAlViRdGeKkc inAeevVaGDlVEvKgGDri PADlRvasaqgcKVDNSSLT GESEPQtRspdfsnenP..L ETrNiaFfSTncvEGTarGv VintGDrTvmGRIAtLASsl evgrTPIsiEIeHFihiItG vAvflGvsFFilslilg... YawLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmAkK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgtsfdrsSatwaaLaria gLCNRAvFl........... .......aeqsnvPilKrdv aGDASEsALLKciElccGs. .vndmRdkhvKiaEIPFNST NKyQlSIHknans....... ....eeskhllVMKGAPERi LdrCStImi.hGkEqpLDde mkdaFqnAYveLGGlGERVL GFChyfLpddqfaegfqFdt eev.NFPtenLcFiGLmSMI DPPRaaVlDAVgKCRspGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipi neVNp......rdAkAcVvh GgeLkdltpeqlddiLkhht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLlfIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEa aEsDIMkrq.PRnprtDk.. .................... .................... ...................L VNerLisiaYgQIGmmQata GFftYFvilAenG....... .flPstLlgiRvkWddkyvn DleDSYGQqWTyeqRkivey TchTsFFasIvivQwaDLiI cKTRRnSiiqQG.mkNkili fglfeetalaafLsYcPGmd valrmypl.kpswWfcafPy sllIflYDEaRrfilRrnPd g.WveretYY.......... 
  108  P25489    Catostomus commersoni                       ................mgvg dgrdqyelaamseqsgkkks knkkekkekdmdelKkEvdl ddHklsleElhhkygtdlsk GLsnsrAeeiLarDGPNaLt PPptTPEwvKFckqmfGGfs mLlWtgAvlCflAygIlaam edepan..DNLYLgvvLsaV ViiTGcFsYYQdaKSskImd SFknlvPQqAlVvRdGeKkq inAeevViGDlVEvKgGDri PADlRiisshgcKVDNSSLT GESEPQtRspdfsndnP..L ETkNiaFfSTncvEGTarGi VistGDrTvmGRIAtLASGl evgrTPIsiEIeHFihiItG vAvflGvsFlllslvlg... YswLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmAkK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEn......... qsgtsfdrsSdtwasLaria gLCNRAvFl........... .......aeqidvPilKrdv aGDASEsALLKciElccGs. .vkemRekftKvaEIPFNST NKyQlSvHkipsgg...... ....kesqhllVMKGAPERi LdrCatImi.qGkEqlLDde ikesFqnAYleLGGlGERVL GFChfyLpdeqfPegfqFda ddv.NFPtenLcFvGLmSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv neVNp......rdAkAcVvh GgdLkdlsceqlddiLkyht EIVFARTSPQQKLiIVEgCQ RtGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLffIianiPLPlGtvT ILcIDLgTDmlPaiSLAYEa aEsDIMkrq.PRnpktDk.. .................... .................... ...................L VNerLisiaYgQIGmiQala GFftYFvilAenG....... .flPprLlgiRmnWddkyin DleDSYGQqWTyeqRkivef TchTaFFtsIvivQwaDLiI cKTRRnSvFqQG.mkNkili fglfeetalaafLsYcPGmd valrmypl.kpnwWfcafPy sllIfiYDEiRklilRrnPG g.WmeretYY.......... 
  109  P50993    Homo sapiens               ATP1A2 / NaKa2   .................... .mgrgagreyspaattaeng ggkkkqkekeldelKkEvam ddHklsldElgrkyqvdlsk GLtnqrAqdvLarDGPNaLt PPptTPEwvKFcrqlfGGfs iLlWigAilCflAygIqaam edepsn..DNLYLgvvLaaV VivTGcFsYYQEaKSskImd SFknmvPQqAlViReGeKmq inAeevVvGDlVEvKgGDrv PADlRiisshgcKVDNSSLT GESEPQtRspefThenP..L ETrNicFfSTncvEGTarGi ViatGDrTvmGRIAtLASGl evgrTPIAmEIeHFiqlItG vAvflGvsFFvlslilg... YswLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEd......... qsgatfdkrSptwtaLsria gLCNRAvFk........... .......agqenisvsKrdt aGDASEsALLKciElscGs. .vrkmRdrnpKvaEIPFNST NKyQlSIHereds....... .....pqshvlVMKGAPERi LdrCStIlv.qGkEipLDke mqdaFqnAYmeLGGlGERVL GFCqlnLpsgkfPrgfkFdt del.NFPtekLcFvGLmSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipm sqVNp......reAkAcVvh GsdLkdmtseqldeiLknht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGiAMGIsGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLlfIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEa aEsDIMkrq.PRnsqtDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvilAenG....... .flPsrLlgiRldWddrtmn DleDSYGQeWTyeqRkvvef TchTaFFasIvvvQwaDLiI cKTRRnSvFqQG.mkNkili fglleetalaafLsYcPGmg valrmypl.kvtwWfcafPy sllIfiYDEvRklilRryPG g.WveketYY.......... 
 (109) P24797    Gallus gallus              ATP1A2 / NaKa2   .................... ....mdgreyspaattseng ggrrkqkekeldelKkEvnl ddHklsldElgrkyqvdlsr GLsnarAaevLaqDGPNaLt PPptTPEwvKFcrqlfGGfs iLlWigAilCflAygIqaam edepsn..DNLYLgvvLaaV VivTGcFsYYQEaKSskImd SFknmvPQqAlViReGeKiq inAenvVvGDlVEvKgGDrv PADmRiisshgcKVDNSSLT GESEPQtRspefThenP..L ETrNicFfSTncvEGTarGi VistGDrTvmGRIAsLASGl evgrTPIAmEIeHFirlItG vAvflGlsFFilslilg... YtwLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEd......... qsgatfdkrSptwaaLsria gLCNRAvFk........... .......pgqenisisKrdt aGDASEsALLKciqlscGs. .vkkmRdknpKvtEIPFNST NKyQlSIHereed....... .....pqghilVMKGAPERi LerCSrIll.qGqEvpLDee mkeaFqnAYleLGGlGERVL GFChlyLppdkfPrgfrFda dev.NFPtsdLcFvGLmSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv sqVNp......reAkAcVvh GsdLkdmtaeqldeiLrnht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGiAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLlfIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEa aEsDIMkrq.PRnprtDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvilAenG....... .flParLlgvRlaWddrstn DleDSYGQeWTyeqRkvvef TchTaFFasIvvvQwaDLiI cKTRRnSvFqQG.mkNkili fglleetalaafLsYcPGmg valrmypl.kvtwWfcafPy sllIfaYDEvRklilRryPG g.WveketYY.......... 
 (109) P06686    Rattus norvegicus          ATP1A2 / NaKa2   .................... .mgrgagreyspaattaeng ggkkkqkekeldelKkEvam ddHklsldElgrkyqvdlsk GLtnqrAqdiLarDGPNaLt PPptTPEwvKFcrqlfGGfs iLlWigAllCflAygIlaam edepsn..DNLYLgivLaaV VivTGcFsYYQEaKSskImd SFknmvPQqAlViReGeKmq inAeevVvGDlVEvKgGDrv PADlRiisshgcKVDNSSLT GESEPQtRspefThenP..L ETrNicFfSTncvEGTarGi ViatGDrTvmGRIAtLASGl evgqTPIAmEIeHFiqlItG vAvflGvsFFvlslilg... YswLeAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD nqIheADTtEd......... qsgatfdkrSptwtaLsria gLCNRAvFk........... .......agqenisvsKrdt aGDASEsALLKciElscGs. .vrkmRdrnpKvaEIPFNST NKyQlSIHereds....... .....pqshvlVMKGAPERi LdrCStIlv.qGkEipLDke mqdaFqnAYmeLGGlGERVL GFCqlnLpsgkfPrgfkFdt del.NFPtekLcFvGLmSMI DPPRaaVPDAVgKCRsAGIk VIMVTGDHPITAKAIAkgVG IISegnETVEDIAaRlnipv sqVNp......reAkAcVvh GsdLkdmtseqldeiLrdht EIVFARTSPQQKLiIVEgCQ RqGaiVAVTGDGVNDSPALK KADIGiAMGIsGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLlfIianiPLPlGtvT ILcIDLgTDmvPaiSLAYEa aEsDIMkrq.PRnsqtDk.. .................... .................... ...................L VNerLismaYgQIGmiQalg GFftYFvilAenG....... .flPsrLlgiRldWddrttn DleDSYGQeWTyeqRkvvef TchTaFFasIvvvQwaDLiI cKTRRnSvFqQG.mkNkili fglleetalaafLsYcPGmg valrmypl.kvtwWfcafPy sllIfiYDEvRklilRryPG g.WveketYY.......... 
  110  Q64541    Rattus norvegicus          ATP1A4 / NaKa4   ..............mepgke taatseqkprptlrasntnr qpkvkrrkkdleelKkEvvm ddHkltldElsakysvdltk GLsvtdAqeiLtlnGPNvLt PPptTPEwiKFckqlfGGfs lLlWtgsllCflAygIhvsy yqenank.DNLYLgivLsaV ViiTGcFsYYQEaKSskIme SFktmvPQqAlViRdGeKmq invrdvVlGDlVEvKgGDqv PADiRviaaqgcKVDNSSLT GESEPQsRcpdcThenP..L ETrNiiFfSTncvEGTarGv ViatGDhTvmGRIAsLtSGl tmgkTPIAtEIeHFihiIta vAvflGvtFFflslilg... YtwLdAviFligIiVAnVPE GLLATVTVcLtLTAKRmArK NClVKNLEAVETLGSTStIC SDKTGTLTQNRMTVaHlWFD ktvyeADTsEeq........ ttgktfpksSdtwfyLaria gLCNRAdFk........... .......phqeslPitKrtt tGDASEsALLKfiEqsysp. .vsemRqknpKvaEIPFNST NKyQmSIHlledn....... .....seahvllMKGAPERi LdfCSsfll.nGqEypmDee mktdFqnAYieLGGlGERVL GFCflnLpsn.fskgfqFnt eel.NFPmenLcFaGLiSMI DPPRtaVPDAVsKCRsAGIk VIMVTGDHPITAKAIAksVG IISeanETaEDIAaRlnisi sqVsn......ksikAiVvh GseLkdmdsgqldniLksyk EIVFARTSPQQKLiIVEgCQ RlGaiVAVTGDGVNDSPALK KADIGiAMGItGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLTsNIPE itPfLlfIvlsiPLPlGtiT ILcIDLgTDmvPaiSLAYEt pEsDIMkrl.PRnpktDn.. .................... .................... ...................L VNdrLigmaYgQIGmiQala GFftYFvilAenG....... .fkPldLlgiRlyWddtnln DleDtYGQqWTyeqRkvvef TcqTaFFisIvivQwaDLiI cKTRRnSlFkQG.mkNkvli fglleetilaacLsYiPGmd valrmypl.kinwWfcalPy svlIfiYDEvRkliiRrrPG g.WleketYY.......... 
  111  P17326    Artemia franciscana                         .................... .................... ..mgkkqgkqlsdlKkElel dqHkipleElcrrlgtntet GLtssqAkshLekyGPNaLt PPrtTPEwiKFckqlfGGfq mLlWigsilCfiAytmekyk n.pdvlg.DNLYLglaLlfV VimTGcFaYYQdhnaskImd SFknlmPQfAfViRdGkKiq lkAeevtvGDlVEvKfGDri PADiRitscqsmKVDNSSLT GESEPQsRstecTndnP..L ETkNlaFffTntlEGTgrGi VinvGDdsvmGRIAcLASsl dsgkTPIArEIeHFihiIta mAvslaavFavisflyg... YtwLeAaiFmigIiVAkVPE GLLATVTVcLtLTAKRmAkK NClVrNLEAVETLGSTStIC SDKTGTLTQNRMTVaHmWFD qkIvtADTtEn......... qsgnqlyrgSkgfpeLirva sLCsRAeFk........... .......tehahlPvlKrdv nGDASEaAiLKfaEmstGs. .vmniRskqkKvsEIPFNSa NKyQvSvHeredk....... ....sg..yflVMKGAPERi LerCStIli.dGtEipLDnh mkecFnnAYmeLGGmGERVL GFCdfeLpsdqyPrgyvFda dep.NFPisgLrFvGLmSMI DPPRaaVPDAVsKCRsAGIk VIMVTGDHPITAKAIArqVG IISeghETVdDIAaRlnipv seVNp......rsAqAaVih GndLkdmnsdqlddiLrhyr EIVFARTSPQQKLiIVEgvQ RqGefVAVTGDGVNDSPALK KADIGvAMGIaGSDvsKqAA DMILLDDNFASIVTGVEEGR LIFDNiKKSIAYTLTskIPE lsPfLmyIlfdlPLaiGtvT ILcIDLgTDvvPaiSmAYEg pEaDprk...PRdpvkek.. .................... .................... ...................L VNerLismaYgQIGvmQafg GFftYFvimgecG....... .flPnrLfglRkwWeskayn DltDSYGQeWTwdaRkqley TchTaFFisIvivQwtDLiI cKTRRlSlFqQG.mkNgtln falvfetcvaafLsYtPGmd kglrmypl.kiwwWfppmPf sllIlvYDEcRkflmRrnPG g.fleretYY.......... 
  112  P20648    Homo sapiens               ATP4A            ........mgkaenyelysv elgpgpggdmaakmskkkka gggggkrkeklenmKkEmei ndHqlsvaEleqkyqtsatk GLsaslAaelLlrDGPNaLr PPrgTPEyvKFarqlaGGlq cLmWvaAaiCliAfaIqase gdlttd..DNLYLaiaLiaV VvvTGcFgYYQEfKStnIia SFknlvPQqAtViRdGdKfq inAdqlVvGDlVEmKgGDrv PADiRilaaqgcKVDNSSLT GESEPQtRspecThesP..L ETrNiaFfSTmclEGTaqGl VvntGDrTiiGRIAsLASGv enekTPIAiEIeHFvdiIaG lAilfGatFFivamcig... YtfLrAmvFfmaIvVAyVPE GLLATVTVcLsLTAKRlAsK NCvVKNLEAVETLGSTSvIC SDKTGTLTQNRMTVsHlWFD nhIhtADTtEd......... qsgqtfdqsSetwraLcrvl tLCNRAaFk........... .......sgqdavPvpKriv iGDASEtALLKfsEltlGn. .amgyRdrfpKvcEIPFNST NKfQlSIHtledp....... ....rdprhllVMKGAPERv LerCSsIli.kGqElpLDeq wreaFqtAYlsLGGlGERVL GFCqlyLnekdyPpgyaFdv eam.NFPssgLcFaGLvSMI DPPRatVPDAVlKCRtAGIr VIMVTGDHPITAKAIAasVG IISegsETVEDIAaRlrvpv dqVNr......kdArAcVin GmqLkdmdpselveaLrthp EmVFARTSPQQKLvIVEsCQ RlGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDaaKnAA DMILLDDNFASIVTGVEqGR LIFDNLKKSIAYTLTkNIPE ltPyLiyItvsvPLPlGciT ILfIeLcTDifPsvSLAYEk aEsDIMhlr.PRnpkrDr.. .................... .................... ...................L VNepLaaysYfQIGaiQsfa GFtdYFtamAqeG....... .wfPllcvglRaqWedhhlq DlqDSYGQeWTfgqRlyqqy TcyTvFFisIevcQiaDvlI rKTRRlSaFqQGffrNkilv iaivfqvcigcfLcYcPGmp nifnfmpi.rfqwWlvplPy gilIfvYDEiRklgvRccPG s.WwdqelYY.......... 
 (112) P50996    Canis familiaris           ATP4A            ........mgkaenyemysv elgpgpggdmaakms.kkka gkgggkkkeklenmKkEmei ndHqlsvaEleqkyqtsatk GLsaslAadlLlrDGPNaLr PPrgTPEyvKFarqlaGGlq cLmWvaAaiCliAfaIqase gdlttd..DNLYLalaLiaV VvvTGcFgYYQEfKStnIia SFknlvPQqAtViRdGdKfq inAdqlVvGDlVEmKgGDrv PADiRilqaqgcKVDNSSLT GESEPQtRspecThesP..L ETrNialfSTmclEGTaqGl VvntGDrTiiGRIAsLASGv enekTPIAiEIeHFvdiIaG lAilfGatFFvvamcig... YtfLrAmvFfmaIvVAyVPE GLLATVTVcLsLTAKRlAsK NCvVKNLEAVETLGSkSvIC SDKTGTLTQNsMTVsnlWFD nhIhtADTtEd......... qsgqkfdqsSetwraLcrvl tLCNRAaFk........... .......sgqdavPvpKriv iGDASEtALLKfsEltlGn. .amgyRerfpKvcEIPFNST NKfQlSIHtledp....... ....rdprhvlVMKGAPERv LerCSsIli.kGqElpLDeq wreaFqtAYlsLGGlGERVL GFCqlyLsekdyPpgyaFdv eam.NFPtsgLcFaGLvSMI DPPRatVPDAVlKCRtAGIr VIMVTGDHPITAKAIAasVG IISegsETVEDIAaRlrvpv dqVNr......kdArAcVin GmqLkdmdpselveaLrthp EmVFARTSPQQKLvIVEsCQ RlGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDaaKnAA DMILLDDNFASIVTGVEqGR LIFDNLKKSIAYTLTkNIPE ltPyLiyItvsvPLPlGciT ILfIeLcTDifPsvSLAYEk aEsDIMhlr.PRnpkrDr.. .................... .................... ...................L VNepLaaysYfQIGaiQsfa GFtdYFtamAqeG....... .wfPllcvglRpyWenhhlq DlqDSYGQeWTfgqRlyqqy TcyTvFFisIemcQiaDvlI rKTRRlSaFqQGffrNrilv iaivfqvcigcfLcYcPGmp nifnfmpi.ryqwWlvpmPf gllIfvYDEiRklgvRccPG s.WwdqelYY.......... 
 (112) Q64436    Mus musculus                                .........mgkekyelysv elgsgpggdmtakms.kkka gggggkkkeklenmKkEmei ndHqlsvsEleqkyqtsatk GLkaslAaelLlrDGPNaLr PPrgTPEyvKFarqlaGGlq cLmWvaAaiCliAfaIqase gdlttd..DNLYLavaLiaV VvvTGcFgYYQEfKStnIia SFknlvPQqAtViRdGdKfq inAdqlVvGDlVEmKgGDrv PADiRilsaqgcKVDNSSLT GESEPQtRspecThesP..L ETrNiaFfSTmclEGTaqGl VvstGDrTiiGRIAsLASGv enekTPIAiEIeHFvdiIaG lAilfGatFFvvamcig... YtfLrAmvFfmaIvVAyVPE GLLATVTVcLsLTAKRlAsK NCvVKNLEAVETLGSTSvIC SDKTGTLTQNRMTVsHlWFD nhIhtADTtEd......... qsgqtfdqsSetwraLcrvl tLCNRAaFk........... .......sgqdavPvpKriv iGDASEtALLKfsEltlGn. .amgyRdrfpKvcEIPFNST NKfQlSIHtledp....... ....rdsrhllVMKGAPERv LerCSsIli.kGqElpLDeq wreaFqtAYlsLGGlGERVL GFCqlyLnekdyPpgyaFdv eam.NFPssgLcFaGLvSMI DPPRatVPDAVlKCRtAGIr VIMVTGDHPITAKAIAasVG IISegsETVEDIAaRlrmpv dqVNr......kdArAcVin GmqLkdmdpselveaLrthp EmVFARTSPQQKLvIVEsCQ RlGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDaaKnAA DMILLDDNFASIVTGVEqGR LIFDNLKKSIAYTLTkNIPE ltPyLiyItvsvPLPlGciT ILfIeLcTDifPsvSLAYEk aEsDIMhlr.PRnpkrDr.. .................... .................... ...................L VNepLaaysYfQIGaiQsfa GFadYFtamAqeG....... .wfPllcvglRpqWedhhlq DlqDSYGQeWTfgqRlyqqy TcyTvFFisIemcQiaDvlI rKTRRlSvFqQGffrNkilv iaivfqvcigcfLcYcPGmp nifnfmpi.rfqwWlvpmPf gllIfvYDEiRklgvRccPG s.WwdqdfYY.......... 
 (112) P27112    Oryctolagus cuniculus      ATP4A            ........mgkadnyelysv elgpgpggdmaakmskkkka gggggkrkeklenmKkEmei ndHqlsvaEleqkyqtsatk GLsarlAaelLlrDGPNaLr PPrgTPEyvKFarqlaGGlq cLmWvaAaiCliAfaIqase gdlttd..DNLYLalaLiaV VvvTGcFgYYQEfKStnIia SFknlvPQqAtViRdGdKfq inAdqlVvGDlVEmKgGDrv PADiRilaaqgcKVDNSSLT GESEPQtRspecThesP..L ETrNiaFfSTmclEGTaqGl VvntGDrTiiGRIAsLASGv enekTPIAiEIeHFvdiIaG lAilfGatFFvvamcig... YtfLrAmvFfmaIvVAyVPE GLLATVTVcLsLTAKRlAsK NCvVKNLEAVETLGSTSvIC SDKTGTLTQNRMTVsHlWFD nhIhtADTtEd......... qsgqtfdqsSetwraLcrvl tLCNRAaFk........... .......sgqdavPvpKriv iGDASEtALLKfsEltlGn. .amgyRdrfpKvcEIPFNST NKfQlSIHtledp....... ....rdprhllVMKGAPERv LerCSsIli.kGqElpLDeq wreaFqtAYlsLGGlGERVL GFChlyLsekdyPpgyaFdv eam.NFPssgLcFaGLvSMI DPPRatVPDAVlKCRtAGIr VIMVTGDHPITAKAIAasVG IISegsETVEDIAaRlrvpv dqVNr......kdArAcVin GmqLkdmdpselveaLrthp EmVFARTSPQQKLvIVEsCQ RlGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDaaKnAA DMILLDDNFASIVTGVEqGR LIFDNLKKSIAYTLTkNIPE ltPyLiyItvsvPLPlGciT ILfIeLcTDifPsvSLAYEk aEsDIMhlr.PRnpkrDr.. .................... .................... ...................L VNepLaaysYfQIGaiQsfa GFtdYFtamAqeG....... .wfPllcvglRpqWedhhlq DlqDSYGQeWTfgqRlyqqy TcyTvFFisIemcQiaDvlI rKTRRlSaFqQGffrNrilv iaivfqvcigcfLcYcPGmp nifnfmpi.rfqwWlvpmPf gllIfvYDEiRklgvRccPG s.WwdqelYY.......... 
 (112) P09626    Rattus norvegicus          ATP4A            .........mgkenyelysv elgtgpggdmaakms.kkka gggggkkkeklenmKkEmem ndHqlsvsEleqkyqtsatk GLkaslAaelLlrDGPNaLr PPrgTPEyvKFarqlaGGlq cLmWvaAaiCliAfaIqase gdlttd..DNLYLalaLiaV VvvTGcFgYYQEfKStnIia SFknlvPQqAtViRdGdKfq inAdqlVvGDlVEmKgGDrv PADiRilsaqgcKVDNSSLT GESEPQtRspecThesP..L ETrNiaFfSTmclEGTaqGl VvstGDrTiiGRIAsLASGv enekTPIAiEIeHFvdiIaG lAilfGatFFvvamcig... YtfLrAmvFfmaIvVAyVPE GLLATVTVcLsLTAKRlAsK NCvVKNLEAVETLGSTSvIC SDKTGTLTQNRMTVsHlWFD nhIhtADTtEd......... qsgqtfdqsSetwraLcrvl tLCNRAaFk........... .......sgqdavPvpKriv iGDASEtALLKfsEltlGn. .amgyRdrfpKvcEIPFNST NKfQlSIHtledp....... ....rdprhllVMKGAPERv LerCSsIli.kGqElpLDeq wreaFqtAYlsLGGlGERVL GFCqlyLnekdyPpgytFdv eam.NFPssgLcFaGLvSMI DPPRatVPDAVlKCRtAGIr VIMVTGDHPITAKAIAasVG IISegsETVEDIAaRlrmpv dqVNk......kdArAcVin GmqLkdmdpselveaLrthp EmVFARTSPQQKLvIVEsCQ RlGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDaaKnAA DMILLDDNFASIVTGVEqGR LIFDNLKKSIAYTLTkNIPE ltPyLiyItvsvPLPlGciT ILfIeLcTDifPsvSLAYEk aEsDIMhlr.PRnprrDr.. .................... .................... ...................L VNepLaaysYfQIGaiQsfa GFadYFtamAqeG....... .wfPllcvglRpqWedhhlq DlqDSYGQeWTfgqRlyqqy TcyTvFFisIemcQiaDvlI rKTRRlSaFqQGffrNrilv iaivfqvcigcfLcYcPGmp nifnfmpi.rfqwWlvpmPf gllIfvYDEiRklgvRccPG s.WwdqelYY.......... 
 (112) P19156    Sus scrofa                 ATP4A            ........mgkaenyelyqv elgpgpsgdmaakms.kkka grgggkrkeklenmKkEmei ndHqlsvaEleqkyqtsatk GLsaslAaelLlrDGPNaLr PPrgTPEyvKFarqlaGGlq cLmWvaAaiCliAfaIqase gdlttd..DNLYLalaLiaV VvvTGcFgYYQEfKStnIia SFknlvPQqAtViRdGdKfq inAdqlVvGDlVEmKgGDrv PADiRilqaqgrKVDNSSLT GESEPQtRspecThesP..L ETrNiaFfSTmclEGTaqGl VvntGDrTiiGRIAsLASGv enekTPIAiEIeHFvdiIaG lAilfGatFFivamcig... YtfLrAmvFfmaIvVAyVPE GLLATVTVcLsLTAKRlAsK NCvVKNLEAVETLGSTSvIC SDKTGTLTQNRMTVsHlWFD nhIhsADTtEd......... qsgqtfdqsSetwraLcrvl tLCNRAaFk........... .......sgqdavPvpKriv iGDASEtALLKfsEltlGn. .amgyRerfpKvcEIPFNST NKfQlSIHtledp....... ....rdprhvlVMKGAPERv LerCSsIli.kGqElpLDeq wreaFqtAYlsLGGlGERVL GFCqlyLsekdyPpgyaFdv eam.NFPtsgLsFaGLvSMI DPPRatVPDAVlKCRtAGIr VIMVTGDHPITAKAIAasVG IISegsETVEDIAaRlrvpv dqVNr......kdArAcVin GmqLkdmdpselveaLrthp EmVFARTSPQQKLvIVEsCQ RlGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDaaKnAA DMILLDDNFASIVTGVEqGR LIFDNLKKSIAYTLTkNIPE ltPyLiyItvsvPLPlGciT ILfIeLcTDifPsvSLAYEk aEsDIMhlr.PRnpkrDr.. .................... .................... ...................L VNepLaaysYfQIGaiQsfa GFtdYFtamAqeG....... .wfPllcvglRpqWenhhlq DlqDSYGQeWTfgqRlyqqy TcyTvFFisIemcQiaDvlI rKTRRlSaFqQGffrNrilv iaivfqvcigcfLcYcPGmp nifnfmpi.rfqwWlvpmPf gllIfvYDEiRklgvRccPG s.WwdqelYY.......... 
  113  Q92126    Xenopus laevis                              ............mgkkeqyd mysvemeregdgamdvkvmk knkaskkkeklesmKkEmdi ndHeitveEleqkyttsvsk GLksafAaevilrDGPNeLk PPkgTPEyiKFarqlaGGlq cLmWvaAviCliAfgIeesq gdltsa..DNLYLaitLiaV VvvTGcFgYYQEfKStnIia SFknlvPQqAtVvRdGdKfq inAnqlVvGDlVEiKgGDrv PADiRiitsqgcKVDNSSLT GESEPQtRspeyThesP..L ETrNiaFfSTmclEGTatGi iintGDrTiiGRIAtLASGv gnekTPIAiEIeHFvdiIaG lAiffGatFFvvamvig... YtfLrAmvFfmaIvVAyVPE GLLATVTVcLsLTAKRlArK NCvVKNLEAVETLGSTSvIC SDKTGTLTQNRMTVsHlWFD nhIhsADTtEd......... qsgqsfdqtSdtwraLskvv sLCNRAfFk........... .......sgqdgiPvpKriv iGDASEtALvKfsEitvGn. .vmeyRerfkKvtEvPFNST NKfQlSIHelqdp....... ....ldlrylmVMKGAPERi LerCStImi.kGqElpLDeq wkeaFqtAYmdLGGlGERVL GFChlyLnekeysrgfnFdt eem.NFPtsgLcFaGLiSMI DPPRatVPDAVmKCRtAGIr VIMVTGDHPITAKAIAasVG IISegsETVEDIAaRlripv eqVNk......rdArAcVin GgqLkemsseelveaLklhp EmVFARTSPQQKLiIVEsCQ klGaiVAVTGDGVNDSPALK KADIGvAMGIaGSDaaKnAA DMILLDDNFASIVTGVEqGR LIFDNLKKSIAYTLTkNIPE laPyLiyItasvPLPlGciT ILfIeLcTDifPsvSLAYEr aEsDIMhlk.PRnprrDr.. .................... .................... ...................L VNeaLavysYfQIGiiQsfa GFvdYFtvmAqeG....... .wfPayvlglRshWenqhlq DlqDSYGQeWTfsqRlyqqy TcyTvFFisyeicQisDvlI rKTRRlSvFqQGffrNkvlv iaivfqlclgnfLcYcPGmp nvfnfmpi.rfqwWlvplPf gilIfvYDEiRklgvRrhPG s.WfdkemYY.......... 
  114  Q64392    Cavia porcellus                             ..........mrrktleiys veldgtkdtkqlgqeegkkc neldlkkssqkeelKkEldl ddHkltseEleqkygtniir GLsstrAaelLarDGPNaLs PPkqTPEiiKFlkqmiGGfs iLlWvgAilCwiAygIqyas nqsgsl..DNvYLgvvLalV VilTGiFaYYQEaKStnIms SFskmiPQeAlVtRdaeKkv ipAeqlVvGDiVEiKgGDqi PADiRllfsqgcKVDNSSLT GESEPQpRsaefThenP..L ETkNiaFySTtclEGTatGm VintGDrTiiGRIAsLASGv gnekTPIAtEIeHFvhivaG vAvsiGilFFiiavslk... YrvLdsiiFligIiVAnVPE GLLATVTVtLsLTAKRmAkK NClVKNLEAVETLGSTSvIC SDKTGTLTQNRMTVaHlWFD sqIftADTsEs......... qsnqafdqsSgtwasLskii aLCNRAeFr........... .......pgqenvPimKrvv vGDASEtALLKfsEvilGd. .vmeiRkrnrKvaEIPFNST NKfQlSIHetedp....... ....gdprflmVMKGAPERi LekCStImi.nGqEqpLDkn nanaFhtAYmeLGGmGERVL GFChlyLpahefPenysFdv dtm.NFPtsnLcFvGLlSMI DPPRstVPDAVaKCRsAGIk VIMVTGDHPITAKAIAksVG IISansETVEDIAkRcniav eqVNk......qdArAaVvt GmeLkdmtpeqldeiLanyp EIVFARTSPQQKLiIVEgCQ RqnavVAVTGDGVNDSPALK KADIGiAMGIaGSDaaKnAA DMvLLDDNFASIVTGVEEGR LIFDNLKKtIAYTLTkNIaE lcPfLvyIivglPLPiGtiT ILfIDLgTDiiPsiaLAYEk vEsDIMnrk.PRhkkkDr.. .................... .................... ...................L VNhqLaiysYlhIGlmQalg aFlvYFtvyAqqG....... .fwPtsLiqlRvkWeqdyvn DleDSYGQqWTryqRkylew TgyTaFFvgImvqQiaDLiI rKTRRnSiFqQGlfrNkviw vgitsqiivaliLscglGsi talnftml.rvqyWfvavPh ailIwvYDEvRklflRlyPG s.WwdknmYY.......... 
 (114) Q9TV53    Oryctolagus cuniculus                       ..........mrqrkleiys velhaatdikkkegrdgkkd ndlelkrnqqkeelKkEldl ddHklsnkEletkygtdiir GlsstrAaelLaqnGPNaLt PPkqTPEiiKFlkqmvGGfs iLlWvgAvlCwiAfgIqyvs npsasl..DrvYLgtvLavV VilTGiFaYYQEaKStnIma SFckmiPQqAvViRdseKkv ipAeqlVvGDiVEiKgGDqi PADiRllsaqgcKVDNSSLT GESEPQsRssgfThenP..L EtkNitFySTtclEGTatGm VintGDrTiiGRIAsLASGv gnekTPIAiEIeHFvhivaG vAvsvGilFFiiavcmk... YhvLdaiiFliaIiVAnVPE GLLATVTVaLsLTAKRvAkK NClVKNLEAVETLGSTSiIC SDKTGTLTQNRMTVaHlWFD nqIfvADTsEd......... nlnqgfdqsSgtwtsLskii aLCNRAeFk........... .......pgeesvPimKrvv vGDASEtALLKfsEvilGd. .vmeiRkrnhKvvEIPFNST NKfQlSIHqtedp....... ....ndkrfllVMKGAPERi LekCStImi.nGkEqpLDks maqaFhtAYmeLGGlGERVL GFChfyLpadefPetysFds esm.NFPtsnLcFvGLlSMI DPPRstVPDAVtKCRsAGIk VIMVTGDHPITAKAIAksVG IISansETVEDIAkRcniav eqVNk......rdAkAaVvt GmeLkdmspeqldelLanyp EIVFARTSPQQKLiIVEgCQ RqdavVAVTGDGVNDSPALK KADIGvAMGItGSDaaKnAA DMiLLDDNFsSIVTGVEEGR LIFDNLKKtIAYTLTkNIaE lcPfLiyIilglPLPiGtiT lLfIDLgTDiiPsiaLAYEk aEsDIMnrk.PRhkkkDr.. .................... .................... ...................L VNqqLavysYlhIGlmQalg aFlvYFtvyAqqG....... .frPtsLfhlRiaWdsdhln DleDnYGqeWTsyqRqylew TgyTaFFvgImvqQiaDLiI rKTRknSiFkQGlfrNkviw vgiasqiivallLsyglGsi talnftml.kaqyWfvavPh ailIwvYDEmRklfiRlyPG s.WwdknmYY.......... 
  115  P54707    Homo sapiens               ATP12A           ....mhqktpeiysvelsgt kdivktdkgdgkekyrglkn nclelkkknhkeefqkElhl ddHklsnrEleekygtdiim GLsstrAaelLarDGPNsLt PPkqTPEivKFlkqmvGGfs iLlWvgAflCwiAygIqyss dksasl..nNvYLgcvLglV VilTGiFaYYQEaKStnIms SFnkmiPQqAlViRdseKkt ipseqlVvGDiVEvKgGDqi PADiRvlssqgcrVDNSSLT GESEPQpRssefThenP..L ETkNicFySTtclEGTvtGm VintGDrTiiGhIAsLASGv gnekTPIAiEIeHFvhivaG vAvsiGilFFiiavslk... YqvLdsiiFligIiVAnVPE GLLATVTVtLsLTAKRmAkK NClVKNLEAVETLGSTSiIC SDKTGTLTQNRMTVaHlWFD nqIfvADTsEd......... hsnqvfdqsSrtwasLskii tLCNRAeFk........... .......pgqenvPimKkav iGDASEtALLKfsEvilGd. .vmeiRkrnrKvaEIPFNST NKfQlSIHemddp....... ....hgkrflmVMKGAPERi LekCStImi.nGeEhpLDks taktFhtAYmeLGGlGERVL GFChlyLpadefPetysFdi dam.NFPtsnLcFvGLlSMI DPPRstVPDAVtKCRsAGIk VIMVTGDHPITAKAIAksVG IISansETVEDIAhRlniav eqVNk......rdAkAaVvt GmeLkdmsseqldeiLanyq EIVFARTSPQQKLiIVEgCQ RqdavVAVTGDGVNDSPALK KADIGiAMGIaGSDaaKnAA DMvLLDDNFASIVTGVEEGR LIFDNLKKtIAYsLTkNIaE lcPfLiyIivglPLPiGtiT ILfIDLgTDiiPsiaLAYEk aEsDIMnrk.PRhknkDr.. .................... .................... ...................L VNqpLavysYlhIGlmQalg aFlvYFtvyAqeG....... .flPrtLinlRveWekdyvn DlkDSYGQeWTryqReylew TgyTaFFvgIlvqQiaDLiI rKTRRnSiFqQGlfrNkviw vgitsqiiigliLsYglGsv talsftml.raqyWfvavPh ailIwvYDEvRklfiRlyPG s.WwdknmYY.......... 
  116  P54708    Rattus norvegicus          ATP12A           ......mrrkteiysvelng tkdvkpadqrddkkfkgakn kdlepnkshekeelKkEldl ddHrlsntEleqkygtniiq GLssvrAtelLarDGPNtLt PPkqTPEiiKFlkqmvGGfs iLlWigAalCwiAfvIqyvn n.sasl..DNvYLgaiLvlV VilTGiFaYYQEaKStnIma SFskmiPQqAlViRdaeKkv isAeqlVvGDvVEiKgGDqi PADiRlvfsqgcKVDNSSLT GESEPQaRstefThenP..L ETkNigFySTtclEGTatGi VintGDrTiiGRIAsLASGv gsekTPIAiEIeHFvhivaG vAvsidiiFFitavcmk... YyvLdAiiFlisIiVAnVPE GLLATVTVtLsLTAKRmAkK NClVKNLEAVETLGSTSiIC SDKTGTLTQNRMTVaHlWFD nqIfvADTsEn......... qtkqafdqsSgtwasLskii tLCNRAeFr........... .......pgqesvPimKrtv vGDASEtALLKfsEvilGd. .vmgiRkrnhKvaEIPFNST NKfQlSIHetedp....... ....nnkrflvVMKGAPERi LekCStImi.nGqEqpLDks sadsFhtAYmeLGGlGERVL GFChlyLpaeqfPqsyiFdv dsv.NFPtsnfcFvGLlSMI DPPRstVPDAVsKCRsAGIk VIMVTGDHPITAKAIAksVG IISannETVEDIAkRrniav eqVNk......reAkAaVvt GmeLkdmtpeqldelLtnyq EIVFARTSPQQKLiIVEgCQ RqdaiVAVTGDGVNDSPALK KADIGiAMGIaGSDaaKnAA DMvLLDDNFASIVTGVEEGR LIFDNLKKtIAYTLTkNIaE lcPfLiyIvaglPLPiGtiT ILfIDLgTDiiPsiaLAYEk aEsDIMnrk.PRhkkkDr.. .................... .................... ...................L VNtqLaiysYlhIGlmQalg GFlvYFtvyAqqG....... .fwPtsLinlRvaWetddin DleDSYGQeWTryqRkylew TgsTaFFvaImiqQiaDLiI rKTRRnSiFqQGlfrNkviw vgiasqvivaliLsYglGsv palsftml.rvqyWfvavPh ailIwvYDEmRklfiRlyPG s.WwdknmYY.......... 
  117  Q92036    Bufo marinus                                mgteansdvystainginei gypdkekeedlglevqkkke kkqkkkkgknvddlKqEldl edHklsieEleakyets.lq GLtsarAaeiLarDGPNtLt PPkgTPEiiKFlkqmiGGfs lLlWagAilCwiAygIlyaq dhntsr..DNLYLgivLavV VilTGcFaYfQEaKStnIma SFnqmiPQqAvVtRnGqKle ipAkdlVvGDlVdvKgGDri PADlRiifaqgcKVDNSSLT GESEaQpRssefThenP..L ETkNiaFySTtclEGTarGf VintGDqTiiGRIAsLASGv gnekTPIAvEIeHFvhivaG vAvsvGvlFFiiaicmg... YsaLnsiiFligIiVAnVPE GLLATVTVtLsLTAKRmAkK NClVKNLEAVETLGSTSiIC SDKTGTLTQNRMTVaHlWFD dhIhiADTsEd......... qshhsfeqtpetwnaLckiv sLCNRAeFk........... .......agqddvPimKkva vGDASEtALLKfsEvitGn. .vmniRsqnrKvcEIPFNST NKfQlSIHetddp....... ....qdqrlllVMKGAPERi LekCStImi.gGkElpLDes mkdsFqtAYmeLGGlGERVL GFChlyLpeeeyPssyaFdi esm.NFPtsnLcFvGLlSMI DPPRstVPDAVtKCRsAGIk VIMVTGDHPITAKAIArsVG IISagsETVdDIAkRlnipv eqVNk......reAkAaVvn GgeLkdmsseelddiLtnha EIVFARTSPQQKLiIVEgCQ RqnyvVAVTGDGVNDSPALK KADIGiAMGIaGSDaaKnAA DMILLDDNFASIVTGVEEGR LIFDNiKKSIgYTLTkNvaE lcPfLiyIiadiPLPiGtiT ILfIDLgTDiiPsvSfAYEk aErDIMnrk.PRrknvDr.. .................... .................... ...................L VNqqLalyaYlQIGiiQsvg aFlnYFtvmAeqG....... .flPhtLvgiRidWekinnq DleDSYGQeWTfsqRqflew TgyTaFFvsIvveQlaDLiI rKTRRnSvFqQGlfrNkfll mglasqviiaafLsYcPemp yalkftpl.raqyWfvaaPy allIfvYDEiRklfiRryPG s.WwdknmYY.......... 
Identical in 33 out of 44 sequences                          -------------------- -------------------- --------------KKE--- --H-----EL-----T---- GL----A-E-L-RDGPNAL- PP--TPE--KF--QL-GGF- -LLW--A-LC--AY-I---- --------DNLYLG--L--V V--TG-F-YYQE-KS--IM- SFKN--PQ-A-V-R-G-K-- --AE--VVGD-VE-KGGDR- PAD-R-----G-KVDNSSLT GESEPQ-RS---T-ENP--L ET-NIAFFST-C-EGTA-G- V--TGD-T--GRIA-LASG- ----TPIA-EIEHF---I-G -AV--G--FF---------- Y--L-A--F--GIIVANVPE GLLATVTVCL-LTAKRMA-K NCLVKNLEAVETLGSTS-IC SDKTGTLTQNRMTV-H-WFD N-I--ADT-E---------- QSG--FD--S-TW--L---- -LCNRA-F------------ ---------Q---P--KR-- -GDASE-ALLK--E---G-- -V---R----K--EIPFNST NK-QLSIH------------ ----------LVMKGAPERI L--CS-I----G-E-PLD-- ----F--AY--LGGLGERVL GFC---L-----P-G--FD- ----NFP---L-F-GL-SMI DPPRA-VPDAV-KCR-AGIK VIMVTGDHPITAKAIA--VG IISEG-ETVEDIA-RL-IPV --VN---------A-A-V-- G--LKD-----LD--L--H- EIVFARTSPQQKL-IVE-CQ R-GAIVAVTGDGVNDSPALK KADIG-AMGIAGSD--K-AA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLT-NIPE --PFL--I----PLPLG--T IL-IDLGTD--P-ISLAYE- AESDIM-R--PR-P--D--- -------------------- -------------------- -------------------L VN--L----Y-QIG-IQA-- GF--YF---A--G------- -F-P--L-G-R--W------ D--DSYGQ-WT--QR---E- TC-T-FF-SI---Q-ADL-I -KTRR-S-FQQG---N--L- -----------FL-Y-PG-- --L---P-----WW----P- --LIF-YDE-RK---R--PG --W---E-YY---------- 
Identical in 37 out of 44 sequences                          -------------------- -------------------- --------------K-E--- --H-----E----------- GL----A---L--DGPN-L- PP--TPE--KF-----GG-- -L-W--A--C--A--I---- --------DNLYL---L--V V--TG-F-YYQE-KS--I-- SF----PQ-A-V-R-G-K-- --A---V-GD-VE-K-GD-- PAD-R-------KVDNSSLT GESEPQ-R----T---P--L ET-N--F-ST---EGT--G- V---GD-T--GRIA-LASG- ----TPIA-EI-HF---I-G -A---G--FF---------- Y--L-A--F---I-VA-VPE GLLATVTV-L-LTAKR-A-K NC-VKNLEAVETLGSTS-IC SDKTGTLTQNRMTV-H-WFD --I--ADT-E---------- ---------S-----L---- -LCNRA-F------------ -------------P--K--- -GDASE-ALLK--E---G-- -----R----K--EIPFNST NK-Q-SIH------------ -----------VMKGAPER- L--CS-I----G-E--LD-- ----F--AY--LGG-GERVL GFC---L-----P----F-- ----NFP---L-F-GL-SMI DPPR--VPDAV-KCR-AGI- VIMVTGDHPITAKAIA--VG IIS---ETVEDIA-R----- --VN---------A-A-V-- G--L-----------L---- EIVFARTSPQQKL-IVE-CQ R-G--VAVTGDGVNDSPALK KADIG-AMGI-GSD--K-AA DMILLDDNFASIVTGVEEGR LIFDNLKKSIAYTLT-NIPE --P-L--I----PLP-G--T IL-IDL-TD--P--SLAYE- -E-DIM----PR----D--- -------------------- -------------------- -------------------L VN--L----Y-QIG--Q--- GF--YF---A--G------- ---P--L---R--W------ D--DSYGQ-WT---R----- T--T-FF--I---Q--DL-I -KTRR-S-F-QG---N---- ------------L-Y-PG-- -------------W----P- ---I--YDE-R----R--PG --W-----YY---------- 
Identical in 42 out of 44 sequences                          -------------------- -------------------- -------------------- -------------------- GL----A---L---G-N-L- PP------------------ -L------------------ -----------Y----L--- V---------Q--K------ -F----P----V-R------ ------V-GD-V----G--- PAD-R--------VD-SSLT GESE-Q-------------- E--N--F-------G---G- ----G--T--G-IA-L---- ---------EI--F------ -A------F----------- --------------VA-VPE GL--TVT--L---A-R-A-K N---K-LE---TLG----I- SDKTGTLT-N-MTV---W-- -------------------- ---------------L---- --C-RA-F------------ -------------------- -GDASE-A------------ -----R----K--E-PFNS- -K---S-H------------ -------------KGAPE-- ---C-------G-------- ----F--AY---G--G-RVL GF---------------F-- ----NF------F-G--S-- DPPR--VP-AV--C--AGI- V-MVTGDHP-TA-AIA---G -I------------------ ---------------A-V-- G--L---------------- --VFARTSP--KL-IV---Q -----V-VTGDGVND-PALK KAD-G-AMGI-GSD--K-AA D--LLDDNF-SIV-G-E-GR LIFDNLKK-I-YT------E --P---------PL------ IL-I-L-TD--P----AYE- -E-DIM----PR-------- -------------------- -------------------- -------------------L V---L----Y---G------ ----YF------G------- ---P---------------- ------G------------- ------F------Q------ --TR--S----G---N---- -------------------- -------------W------ ---I----E-R----R--P- -------------------- 
Identical in all 44 sequences                                -------------------- -------------------- -------------------- -------------------- G-------------G----- PP------------------ -L------------------ -------------------- -------------------- -F----P------R------ --------G-------G--- P------------------T GE------------------ E--N--------------G- ----G-----G-IA------ ---------EI--F------ -------------------- ---------------A-VP- G---T-T--L---A------ ------L------G------ -DKTGTLT-N-MTV---W-- -------------------- -------------------- --C----------------- -------------------- -G---E-------------- -------------E-PFNS- -K------------------ -------------KGAP--- ---C-------G-------- -------AY------G-R-- -F------------------ ------------F-G----- -PP----------C---GI- V-MVTGDH--TA-AI----- -------------------- -----------------V-- G------------------- ---FART-P--K--IV---Q -----V-VTGDG-ND-PA-- KAD-G-AM---G-D--K--A ---LL-DNF-S---G---GR --F-N--K-----------E --P---------P------- ---I-L----------AY-- -E-D---------------- -------------------- -------------------- -------------------L V--------Y---------- -------------------- ---P---------------- -------------------- -------------Q------ ---------------N---- -------------------- -------------------- ----------R--------- -------------------- 
Conserved segments in all P type ATPases                                                                                                                                                                                                                                        aaaaaaaaaaaaaaaaaaa aaaaaa       bbbbbbb bbbbbbbbbbbbb              cccccccccccccc cccccccccccc                                                         dddddddddddddd dddddddddd           eeeeeeeeeeeeeeeeeeee eeeeeeeeeeeeeeee                                                                                                                                                                                                                                                 fffffffffffffff ffffffffffffffffffff ffffffffffffffffffff ff                                                               gggggggggggggggggg gggggggggggggggggggg gggggggg   hhhhhhhhh hhhhhhhhhhhhhhhhhhhh hh
Transmembrane helices                                                                                                                                                       11111111111111 1111111                          22222222 2222222222222                                                                                                                                                 333333333 33333333333                44444444444444 4444                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          55555555555555 555555          6666 66666666666666666                                                                                      7 77777777777777777777 77                                                               888888888888888888 88              9999 999999999999999                 000000000 000000000000
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